Associate Professor, Medicine-Brigham and Women's Hospital, Harvard Medical School
Hematology
Dr. Anthony G. Letai, MD
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Anthony Letai is an expert in the field of Hematology. He attended University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine has a rank of 10 in research and a 19 in primary care He received 1 awards: "Elected Member". Anthony G. Letai, MD is a published doctor and has 26 publications published. The lastest was: 'Cell Death and Cancer Therapy: Don't Forget to Kill the Cancer Cell!' He accepts all Medicare patients.
Publications
- Precision medicine for Cancer with next-generation functional diagnostics.
- Cell Death and Cancer Therapy: Don't Forget to Kill the Cancer Cell!
- Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-Initiating Cells engrafted into immunosuppressed NSG mice.
- Drug-induced death signaling strategy rapidly predicts Cancer response to chemotherapy.
- Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-xL.
- Designed BH3 Peptides with High Affinity and Specificity for Targeting Mcl-1 in Cells.
- APC(Cdc20) Suppresses Apoptosis through Targeting Bim for Ubiquitination and Destruction.
- Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS mutant lung Cancers.
- Selective BCL-2 Inhibition by ABT-199 Causes On Target Cell Death in Acute Myeloid Leukemia.
- Priming BCL-2 to kill: the combination therapy of tamoxifen and ABT-199 in ER+ Breast cancer.
- BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response.
- Mitochondria: gatekeepers of response to chemotherapy.
- High Mitochondrial Priming Sensitizes hESCs to DNA-Damage-Induced Apoptosis.
- Overcoming stroma-mediated treatment resistance in chronic lymphocytic Leukemia through BCL-2 inhibition.
- p53 regulates a non-apoptotic death induced by ROS.
- BH3 profiling in whole Cells by flourimeter or FACS.
- BCL-2 Inhibition: Stemming the Tide of Myeloid Malignancies.
- ABT-199: Taking Dead Aim at BCL-2.
- KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell Acute lymphoblastic leukaemia and Acute ...
- Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML.
- BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death.
- Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma Disease progression.
- Smallpox and smallpox vaccination.
- RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis.
- Bcl-xL controls a switch between Cell death modes during mitotic arrest.
Schools
Pritzker School Of Med University Of Chicago
Brigham and Women39s Hospital
Dana Farber Cancer Institute
Procedures Preformed
- Plasmapheresis
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Anemia
- Antiphospholipid Syndrome (APS)
- Basal Cell Carcinoma
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Elected Member
Education
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Brigham and Women's Hospital -
University of Chicago Pritzker School of Medicine
Hospital
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Brigham and Women's Hospital -
Massachusetts General Hospital -
Dana-Farber Cancer Institute
Drug Facts
| NPI NUMBER | 1851368435 | |
| NPPES Provider LastName | LETAI | |
| NPPES Provider FirstName | ANTHONY | |
| NPPES Provider ZIPCode | 021156013 | |
| NPPES Provider State | MA | |
| Specialty Description | Medical Oncology | |
| Total Claim Count | 12.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1851368435 |
| Last Name Of The Provider | LETAI |
| First Name Of The Provider | ANTHONY |
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