Professor of Medicine, Beth Israel Deaconess Medical Center
Internal Medicine
Dr. Anthony Hollenberg, MD
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Anthony Hollenberg works in the field of Internal Medicine. He has 1 awards "Regional Top Doctor". Anthony Hollenberg has written publications. He has 76 publications published with PubMed. The lastest paper is: 'Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.'
Publications
- Age-related hearing loss and degeneration of cochlear hair cells in mice lacking Thyroid hormone receptor β1.
- NCoR1 and SMRT play unique roles in Thyroid hormone action in vivo.
- Thyroid Hormone Signaling in vivo Requires a Balance Between Coactivators and Corepressors.
- Fibroblast Growth Factor 21 and Thyroid Hormone Show Mutual Regulatory Dependency But Have Independent Actions In Vivo.
- Novel mechanism of positive versus negative regulation by Thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver.
- The in vivo role of nuclear receptor corepressors in Thyroid hormone action.
- Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated Thyroid hormone receptor α.
- Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.
- Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isof...
- Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways.
- PITX2 AND PITX1 regulate thyrotroph function and response to hypoThyroidism.
- Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in paraThyroid carcinoma.
- cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes.
- The nuclear corepressors recognize distinct nuclear receptor complexes.
- Leptin, nutrition, and the Thyroid: the why, the wherefore, and the wiring.
- Thyroid hormone-independent interaction between the Thyroid hormone receptor beta2 amino terminus and coactivators.
- ADD-1 provides major new insight into the mechanism of insulin action.
- p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers.
- Defective release of corepressor by hinge mutants of the Thyroid hormone receptor found in patients with resistance to Thyroid hormone.
- Two separate NCoR (nuclear receptor corepressor) interaction domains mediate corepressor action on Thyroid hormone response elements.
- Isolation and characterization of a novel ligand-dependent Thyroid hormone receptor-coactivating protein.
- A unique role of the beta-2 Thyroid hormone receptor isoform in negative regulation by Thyroid hormone. Mapping of a novel amino-terminal domain important for ligand-i...
- Functional antagonism between CCAAT/Enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter.
- Isoform variable action among Thyroid hormone receptor mutants provides insight into pituitary resistance to Thyroid hormone.
- Function of nuclear co-repressor protein on Thyroid hormone response elements is regulated by the receptor A/B domain.
- A circulating, biologically inactive thyrotropin caused by a mutation in the beta subunit gene.
- Dynamic regulation of gonadotropin-releasing hormone receptor mRNA levels in the anterior pituitary gland during the rat estrous cycle.
- Regulation of chorionic gonadotropin gene expression.
- c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.
- Ligand-independent and -dependent functions of Thyroid hormone receptor isoforms depend upon their distinct amino termini.
- The human thyrotropin-releasing hormone gene is regulated by Thyroid hormone through two distinct classes of negative Thyroid hormone response elements.
- Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from the luteinizing hormone beta gene.
- A novel C-terminal domain in the Thyroid hormone receptor selectively mediates Thyroid hormone inhibition.
- The gene encoding the beta-subunit of rat luteinizing hormone. Analysis of gene structure and evolution of nucleotide sequence.
- Hypercalcemia with low-normal serum intact PTH: a novel presentation of primary hyperparaThyroidism.
- Recent advances in studies of the molecular basis of endocrine disease.
- The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains.
- Transcriptional regulation of the leptin gene promoter in rat GH3 pituitary and C6 glioma cells.
- Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling.
- NPY and MC4R signaling regulate Thyroid hormone levels during fasting through both central and peripheral pathways.
- Resistance to Thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).
- The nuclear receptor corepressor (NCoR) controls Thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-Thyroid axis.
- Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.
- Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity.
- Maintenance of the Thyroid axis during diet-induced obesity in rodents is controlled at the central level.
- Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alpha.
- Leucine at codon 428 in the ninth heptad of Thyroid hormone receptor beta1 is necessary for interactions with the transcriptional cofactors and functions regardless of...
- Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.
- Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin.
- Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites.
- Cellular context of coregulator and adaptor proteins regulates human adenovirus 5 early region 1A-dependent gene activation by the Thyroid hormone receptor.
- Determination of nuclear receptor corepressor interactions with the Thyroid hormone receptor.
- Leptin and melanocortin signaling in the hypothalamus.
- Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation.
- Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons.
- Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.
- Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.
- The thyrotropin-releasing hormone gene is regulated by Thyroid hormone at the level of transcription in vivo.
- Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced Thyroid function: nested case-control and population based study.
- The Thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains.
- The ups and downs of thyrotropin-releasing hormone.
- STAT3 targets the regulatory regions of gluconeogenic genes in vivo.
- The nuclear corepressor, NCoR, regulates Thyroid hormone action in vivo.
- Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor.
- The Thyroid and metabolism: the action continues.
- The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor.
- Activity of androgen receptor antagonist bicalutamide in prostate Cancer cells is independent of NCoR and SMRT corepressors.
- Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells.
- Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor.
- The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for a...
- Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate Cancer cells.
- Regulated production of a peroxisome proliferator-activated receptor-gamma ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes.
- The metabolic and cardiovascular effects of hyperThyroidism are largely independent of beta-adrenergic stimulation.
- Identification and characterization of melanocortin-4 receptor gene mutations in morbidly obese finnish children and adults.
- Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo.
Schools
University of Calgary Faculty of Medicine
Beth Israel Hospital
Massachusetts General Hospital
Conditions Treated
- Thyroid Cancer
Doctors Specialties
- Internal Medicine
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- BlueConnect HMO
- Blue with Managed Care Behavioral Health HMO
- Preferred Blue PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- First Health (Coventry Health Care) PPO
- Choice Care PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Network Health
- Tufts PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Awards
- Regional Top Doctor
Education
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Beth Israel Deaconess Medical Center -
University of Calgary Faculty of Medicine
Hospital
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Beth Israel Deaconess Medical Center
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