Physician
Medical Genetics
Dr. Bruce M. Boman, MD
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Bruce Boman practices Medical Genetics. He went to University of Minnesota Medical School. University of Minnesota Medical School has a rank of 40 in research and a 10 in primary care Dr. Bruce M. Boman is a published doctor and has 100 publications published. The lastest was: 'Co-transfection of MDR1 and MRP antisense RNAs abolishes the drug resistance in multidrug-resistant human lung cancer cells.' He is registered with Medicare.
Publications
- The miRNA23b-regulated signaling network as a key to Cancer development-implications for translational research and therapeutics.
- HOX genes and their role in the development of human Cancers.
- Identification of a developmental gene expression signature, including HOX genes, for the normal human colonic crypt stem cell niche - Overexpression of the signature ...
- Ureteroscopic management of upper tract urothelial carcinoma (UTUC) in patients with Lynch Syndrome (hereditary nonpolyposis colorectal Cancer syndrome).
- Dysplastic lesions in inflammatory bowel disease show increased positivity for the stem cell marker aldehyde dehydrogenase.
- APC +/- alters colonic fibroblast proteome in FAP.
- Detection of DNA mismatch repair proteins in fresh human blood lymphocytes - towards a novel method for hereditary non-polyposis colorectal Cancer (Lynch syndrome) scr...
- Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon Cancer development.
- Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.
- One-hit effects in Cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis.
- Cancer stem cells: a step toward the cure.
- Human colon Cancer stem cells: a new paradigm in gastrointestinal oncology.
- How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon Cancer.
- Searchable high-resolution 2D gel proteome of the human colon crypt.
- Altered gene expression in phenotypically normal Renal cells from carriers of tumor suppressor gene mutations.
- Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.
- The chemopreventive agent sulindac attenuates expression of the antiapoptotic protein survivin in colorectal Carcinoma cells.
- Immunoassay for wild-type protein in lymphocytes predicts germline mutations in patients at risk for hereditary colorectal Cancer.
- Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells.
- An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative ...
- L-tryptophan: a rational anti-depressant and a natural hypnotic?
- Psychosocial stress and ischaemic heart disease: a response to tennant.
- The Indochinese refugee: an overview.
- The Vietnam veteran ten years on.
- Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
- Endobronchial adenoid cystic Carcinoma.
- Immunoassay for thymidylate synthase in cytosols from human colorectal-Carcinoma cell-lines.
- Growth regulation of Gardner's syndrome colorectal Cancer cells by NSAIDs.
- Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase.
- Colorectal Carcinomas with high microsatellite instability: defining a distinct immunologic and molecular entity with respect to prognostic markers.
- Hereditary nonpolyposis colon Cancer: (Lynch syndrome I and II). A challenge for the clinician.
- Hereditary nonpolyposis colorectal Cancer (Lynch syndromes I & II). Genetics, pathology, natural history, and Cancer control, Part I.
- Symmetric division of Cancer stem cells--a key mechanism in tumor growth that should be targeted in future therapeutic approaches.
- Cell cycle and cyclic AMP-dependent phosphorylation of plasma membrane proteins p14 and p24: defects in smooth surface transformed cells.
- Carcinoma of the anal canal. A clinical and pathologic study of 188 cases.
- Cell cycle-associated modulation in cAMP-dependent plasma membrane phosphorylation.
- Manganese and magnesium dependent properties and inner plasma membrane surface localization of guanylate cyclase from murine plasmocytoma cells.
- Topography of protein kinases and phosphoproteins in the plasma membrane of 3T3 cells.
- Biochemical and molecular epidemiology of human Cancer risk.
- Problems in the identification of a Cancer family.
- Phase II study of spirogermanium in patients with advanced colorectal Carcinoma.
- A randomized study of two schedules of copovithane in patients with advanced colorectal Carcinoma.
- Reassignment of a Cancer family syndrome gene to chromosome 18.
- Chromosome 5 allele loss at the glucocorticoid receptor locus in human colorectal Carcinomas.
- Ifosfamide and mesna: marginally active in patients with advanced Carcinoma of the pancreas.
- Phase I study of recombinant gamma-interferon (rIFN-gamma).
- Familial polyposis.
- Hereditary nonpolyposis colorectal Cancer--Lynch syndromes I and II.
- Familial polyposis coli: genetics, surveillance, and treatment.
- The role of vitamin D3 in the proliferation of a human colon Cancer cell line in vitro.
- AdenoCarcinoma of the small bowel in lynch syndrome II.
- Phase II study of adriamycin with sequential methotrexate and 5-fluorouracil (AMF) in gastric Carcinoma.
- Phase II study of fludarabine phosphate in patients with advanced colorectal Carcinoma.
- Increased expression of the retinoblastoma gene in human colorectal Carcinomas relative to normal colonic mucosa.
- Specific expression of proteins and phosphoproteins in 3T3 T mesenchymal stem cells at distinct growth arrest and differentiation states.
- Primary Lymphoma of bone.
- A phase II study of trimetrexate therapy for metastatic colorectal Carcinoma.
- Extrachromosomal amplification of the epidermal growth factor receptor gene in a human colon Carcinoma cell line.
- Application of positron emission tomography to neurological oncology.
- Cellular growth response to epidermal growth factor in colon Carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous pol...
- Hereditary colorectal Cancer.
- Genetic changes at the beta-2-adrenergic receptor locus on chromosome 5 in human colorectal Carcinomas.
- Colon Cancer genetics.
- The effects of steroid hormones on a human colon Cancer cell line in vitro.
- Growth effects of tamoxifen on Lovo colon Carcinoma cells and cultured cells from normal colonic mucosa.
- Characterization of beta-adrenergic receptors in DiFi and HT-29 cells.
- A study of chromosome 6 allele loss in human colorectal Carcinomas.
- Characteristics of alpha-adrenoceptors in two human colorectal Cancer cell lines.
- Molecular genetic markers in familial adenomatous polyposis.
- Expression of the gene coding for the light chain of calpactin I (annexin II) in cell lines DiFi, HT-29, and WI-38.
- Manganese- and magnesium-dependent activities of soluble and particulate guanylate cyclase from sheep Kidney outer medulla.
- Development of cross-resistance to tamoxifen in raloxifene-treated Breast carcinoma cells.
- Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon Cancer.
- Computer modeling implicates stem cell overproduction in colon Cancer initiation.
- Colorectal Cancer staging and adjuvant chemotherapy.
- Postoperative management of local colorectal Cancer: therapy and surveillance.
- Tumor-specific expression of anti-mdr1 ribozyme selectively restores chemosensitivity in multidrug-resistant colon-adenoCarcinoma cells.
- Co-transfection of MDR1 and MRP antisense RNAs abolishes the drug resistance in multidrug-resistant human lung Cancer cells.
- Isolation of normal human colonic mucosa: comparison of methods.
- Synthetic retrotransposon vectors for gene therapy.
- RB1 protein in normal and malignant human colorectal tissue and colon Cancer cell lines.
- Retinoblastoma gene product-associated proteins in human colon Cancer cell lines.
- Positron emission tomography for preoperative staging of colorectal Carcinoma.
- Down-modulation of epidermal growth factor receptor accompanies TNF-induced differentiation of the DiFi human adenoCarcinoma cell line toward a goblet-like phenotype.
- Biologic functions of the genes responsible for familial Cancer.
- Does the human retinoblastoma gene have a role in colon Cancer?
- Phosphorylation of the adenomatous polyposis coli protein and its possible regulatory effects in cells.
- Radioimmunoassay of the APC gene product using antibodies against its middle and carboxyl regions.
- Immunodetection of the presence or absence of full-length APC gene product in human colonic Tissues.
- Purification of the adenomatous polyposis coli (APC) gene product.
- Monoclonal antibodies: the next attempt at tumor immunotherapy.
- Cell surface characteristics of proadipocytes growth arrested at the predifferentiation GD state. Defects associated with neoplastic transformation.
- Concurrent use of ECT and cholinesterase inhibitor medications.
- Optimized procedures for microarray analysis of histological specimens processed by laser capture microdissection.
- Use of RNA amplification in the optimal characterization of global gene expression using cDNA microarrays.
- Analyzing alkaline proteins in human colon crypt proteome.
- Spontaneous immortalization of clinically normal colon-derived fibroblasts from a familial adenomatous polyposis patient.
- A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis.
- Microsatellite status and cell cycle associated markers in rectal Cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy.
Schools
University Of Minnesota Medical School
Mayo Medical Center
National Institute Of Health
Conditions Treated
- Anemia
- Bladder Cancer
- Breast Cancer
- Carcinoma in Situ
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Doctors Specialties
- Medical Oncology
- Oncology
- Medical Genetics
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
Mayo School of Graduate Medical Education -
University of Minnesota Medical School
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1275556516 |
| Last Name Of The Provider | BOMAN |
| First Name Of The Provider | BRUCE |
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