Van Vleet Chair and Professor of Pharmacology, University of Tennessee, Memphis, College of Medicine
Endocrinology
Dr. Burt M. Sharp, MD
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Burt M. Sharp is an expert in the field of Endocrinology. He studied medicine at University of Cincinnati College of Medicine. Burt Sharp is also published. He has 101 publications published. The lastest publication: "Delta-opioid suppression of human immunodeficiency virus-1 expression in T cells (Jurkat).'
Publications
- Basolateral amygdala and ventral hippocampus in stress-induced amplification of nicotine self-administration during reacquisition in rat.
- Amplified reacquisition of nicotine self-administration in rats by repeated stress during abstinence.
- Protection Genes in Nucleus Accumbens Shell Affect Vulnerability to Nicotine Self-Administration across Isogenic Strains of Adolescent Rat.
- Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in ad...
- Fostering itself increases nicotine self-administration in young adult male rats.
- Genetic factors control nicotine self-administration in isogenic adolescent rat strains.
- Nicotine modulates multiple regions in the limbic stress network regulating activation of hypophysiotrophic neurons in hypothalamic paraventricular nucleus.
- Social Interaction Promotes Nicotine Self-Administration with Olfactogustatory Cues in Adolescent Rats.
- Local immune response to tissue and nerve injury mediates opioid antinociception.
- Nicotine self-administration differentially regulates hypothalamic corticotropin-releasing factor and arginine vasopressin mRNAs and facilitates stress-induced neurona...
- Chronic nicotine self-administration augments hypothalamic-pituitary-adrenal responses to mild acute stress.
- Stromal cell-derived factor 1-alpha (SDF)-induced human T cell chemotaxis becomes phosphoinositide 3-kinase (PI3K)-independent: role of PKC-theta.
- Acquisition of nicotine self-administration in adolescent rats given prolonged access to the drug.
- Nicotine-induced norepinephrine release in hypothalamic paraventricular nucleus and amygdala is mediated by N-methyl-D-aspartate receptors and nitric oxide in the nucl...
- Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration.
- delta opioid receptors stimulate Akt-dependent phosphorylation of c-jun in T cells.
- Multiple opioid receptors on immune cells modulate intracellular signaling.
- Effects of galantamine, a nicotinic allosteric potentiating ligand, on nicotine-induced catecholamine release in hippocampus and nucleus accumbens of rats.
- Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the alpha6 subunit.
- Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats.
- Opioid receptor expression and intracellular signaling by cells involved in host defense and immunity.
- Chronic self-administration of nicotine in rats impairs T cell responsiveness.
- beta-Endorphin immunoreactivity and acute behavioral distress in children with leukemia.
- Metoclopramide, a dopamine antagonist, stimulates aldosterone secretion in rhesus monkeys but not in dogs or rabbits.
- Opioid peptides rapidly stimulate superoxide production by human polymorphonuclear leukocytes and macrophages.
- Expression and function of proenkephalin A messenger ribonucleic acid in murine fetal thymocytes.
- Pain killers of the immune system.
- CSF beta-endorphin-immunoreactivity in normal, schizophrenic, depressed, manic and anorexic subjects.
- Met-enkephalin-containing peptides encoded by proenkephalin A mRNA expressed in activated murine thymocytes inhibit thymocyte proliferation.
- The delta1-opioid receptor antagonist, 7-(benzospiroindanyl)naltrexone [correction of 7-benzylspiroindanylnaltrexone], prolongs renal allograft survival in a rat model.
- Adrenocortical response to corticotropin is inhibited by gamma 3-MSH antisera in normotensive and spontaneously hypertensive rats.
- Opioid-mediated suppression of interferon-gamma production by cultured peripheral blood mononuclear cells.
- Induction of the messenger ribonucleic acid for proenkephalin A in cultured murine CD4-positive thymocytes.
- Effects of morphine addiction on the pathogenesis of murine toxoplasmosis.
- Opiates, human peripheral blood mononuclear cells, and HIV.
- Beta-endorphin stimulates human polymorphonuclear leukocyte superoxide production via a stereoselective opiate receptor.
- Cellular mechanisms involved in the modulation of the immune system by drugs of abuse.
- Delta-opioid suppression of human immunodeficiency virus-1 expression in T cells (Jurkat).
- Delta-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element.
- Modulatory effects of beta-endorphin on interferon-gamma production by cultured peripheral blood mononuclear cells: heterogeneity among donors and the influence of cul...
- Neurotransmitter control of hypothalamic-pituitary-thyroid function in rats.
- Beta-endorphin binding to naloxone-insensitive sites on a human mononuclear cell line (U937): effects of cations and guanosine triphosphate.
- Expression of naloxone-resistant beta-endorphin binding sites on A20 cells: effects of concanavalin A and dexamethasone.
- The role of opiates and endogenous opioid peptides in the regulation of rat TSH secretion.
- Lethality of morphine in mice infected with Toxoplasma gondii.
- IL-1 beta modulates the concanavalin-A-induced expression of proenkephalin A mRNA in murine thymocytes.
- Corticotropin-releasing factor in cerebellar afferent systems: a combined immunohistochemistry and retrograde transport study.
- Effects of immobilization stress on the pathogenesis of acute murine toxoplasmosis.
- Protein kinase A regulates nicotinic cholinergic receptors and subunit messenger ribonucleic acids in PC 12 cells.
- Brain nicotinic receptors isolated by a monospecific antibody against a synthetic alpha-3 subunit receptor peptide compared to a monoclonal anti-idiotypic (to nicotine...
- Evidence for opioid receptors on cells involved in host defense and the immune system.
- Nerve growth factor enhances [3H]nicotine binding to a nicotinic cholinergic receptor on PC 12 cells.
- Lymphocyte modulation by seven transmembrane receptors: a brief review of session 1.
- Prostaglandins mediate the adrenocorticotropin response to tumor necrosis factor in rats.
- Tumor necrosis factor-alpha is a potent ACTH secretagogue: comparison to interleukin-1 beta.
- Induction and Desensitization of the c-Fos mRNA Response to Nicotine in Rat Brain.
- N-acetyl-beta-endorphin1-31 antagonizes the suppressive effect of beta-endorphin1-31 on murine splenocyte proliferation via a naloxone-resistant receptor.
- Murine splenocytes express a naloxone-insensitive binding site for beta-endorphin.
- Characterization of a naloxone-insensitive beta-endorphin receptor on murine peritoneal macrophages.
- Gene expression in accumbens GABA neurons from inbred rats with different drug-taking behavior.
- Beta-endorphin enhances Concanavalin-A-stimulated calcium mobilization by murine splenic T cells.
- Distribution of nicotinic binding sites with respect to CRF and neurophysin immunoreactive perikarya within the rat hypothalamus.
- The adrenocorticotropin response to interleukin-1 beta instilled into the rat median eminence depends on the local release of catecholamines.
- Prostaglandins mediate the ACTH response to interleukin-1-beta instilled into the hypothalamic median eminence.
- A central mechanism is involved in the secretion of ACTH in response to IL-6 in rats: comparison to and interaction with IL-1 beta.
- Interleukin-1 alpha and interleukin-1 beta stimulate adrenocorticotropin secretion in the rat through a similar hypothalamic receptor(s): effects of interleukin-1 rece...
- Regulation of the messenger ribonucleic acid for corticotropin-releasing factor in the paraventricular nucleus and other brain sites of the rat.
- Selective administration of nicotine into catecholaminergic regions of rat brainstem stimulates adrenocorticotropin secretion.
- Nicotinic activation of CRH neurons in extrahypothalamic regions of the rat brain.
- Nicotine regulates nicotinic cholinergic receptors and subunit mRNAs in PC 12 cells through protein kinase A.
- Catecholamines mediate nicotine-induced adrenocorticotropin secretion via alpha-adrenergic receptors.
- Monospecific antibodies against a synthetic peptide predicted from the alpha-3 nicotinic receptor cDNA inhibit binding of [3H]nicotine to rat brain nicotinic cholinerg...
- Activation of protein kinase C rapidly down-regulates naloxone-resistant receptors for beta-endorphin on U937 cells.
- Rapid desensitization of the acute stimulatory effects of nicotine on rat plasma adrenocorticotropin and prolactin.
- Characterization of antisera to the naloxone-insensitive receptor for beta-endorphin on U937 cells generated by using the complementary peptide strategy.
- Nicotine elevates rat plasma ACTH by a central mechanism.
- Biochemical characterization of naloxone-resistant receptors for beta-endorphin on a human mononuclear cell line (U937) and murine splenocytes.
- Dual signal transduction through delta opioid receptors in a transfected human T-cell line.
- Expression of delta opioid receptors and transcripts by splenic T cells.
- Signaling through delta opioid receptors on murine splenic T cells and stably transfected Jurkat cells.
- Response of the hypothalamo-pituitary-adrenal axis to nicotine.
- Inhibition of nicotine-induced hippocampal norepinephrine release in rats by alpha-conotoxins MII and AuIB microinjected into the locus coeruleus.
- Self-administration in rats allowed unlimited access to nicotine.
- Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: dose-dependency an...
- Immunofluorescence detection of delta opioid receptors (DOR) on human peripheral blood CD4+ T cells and DOR-dependent suppression of HIV-1 expression.
- Nicotine stimulates the expression of cFos protein in the parvocellular paraventricular nucleus and brainstem catecholaminergic regions.
- Nicotine-induced cFos expression in the hypothalamic paraventricular nucleus is dependent on brainstem effects: correlations with cFos in catecholaminergic and noncate...
- Nicotinic agonists administered into the fourth ventricle stimulate norepinephrine secretion in the hypothalamic paraventricular nucleus: an in vivo microdialysis study.
- Desensitization and resensitization of norepinephrine release in the rat hippocampus with repeated nicotine administration.
- Adrenocorticotropin response and nicotine-induced norepinephrine secretion in the rat paraventricular nucleus are mediated through brainstem receptors.
- Nicotine activates NPY and catecholaminergic neurons in brainstem regions involved in ACTH secretion.
- The brain-immune axis: role of opiates and other substances of abuse, the hypothalamic-pituitary-adrenal axis and behavior.
- The role of the fourth cerebroventricle in nicotine-stimulated prolactin release in the rat: involvement of catecholamines.
- Detection of basal levels and induction of delta opioid receptor mRNA in murine splenocytes.
- Antiproliferative effects of delta opioids on highly purified CD4+ and CD8+ murine T cells.
- Role of the fourth cerebroventricle in mediating rat plasma ACTH responses to intravenous nicotine.
- Delta opioid agonists inhibit proliferation of highlypurified murine CD4+ and CD8+ T-cells.
- Attenuation of the plasma prolactin response to restraint stress after acute and chronic administration of nicotine to rats.
- Expression of delta opioid receptors by splenocytes from SEB-treated mice and effects on phosphorylation of MAP kinase.
- Region-specific transcriptional response to chronic nicotine in rat brain.
Schools
University of Cincinnati Main Campus
Doctors Specialties
- Endocrinology
Accepted Insurances
Education
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University of Cincinnati College of Medicine
Hospital
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University of Tennessee Medical Center
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