Associate Professor of Surgery, Associate Professor of Oncology, Associate Professor of Pathology, Johns Hopkins University School of Medicine
Internal Medicine
Dr. Christopher B. Umbricht, MD
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Christopher Umbricht practices Internal Medicine. Christopher B. Umbricht, MD has written publications. He has 55 publications published with PubMed. The lastest publication is: 'Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1. Its potential role in chromosomal instability.'
Publications
- Lower Vitamin D Levels in Surgical Hyperparathyroidism versus Thyroid Patients.
- Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer.
- Modeling precision treatment of breast cancer.
- HOXB13 Mediates Tamoxifen Resistance and Invasiveness in Human Breast Cancer by Suppressing ERα and Inducing IL-6 Expression.
- Does BRAF V600E Mutation Predict Aggressive Features in Papillary Thyroid Cancer? Results From Four Endocrine Surgery Centers.
- DNA copy number variations characterize benign and malignant thyroid tumors.
- A Tertiary Center's Experience With Second Review of 3885 Thyroid Cytopathology Specimens.
- Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ 2 and RASSF1A in thyroid cancer.
- Three-gene molecular diagnostic model for thyroid cancer.
- Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer.
- Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.
- Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.
- Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
- Chasing "shadows": discovering the subtleties of sestamibi scans to facilitate minimally invasive parathyroidectomy.
- Postoperative hypocalcemia after thyroidectomy for Graves' disease.
- Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.
- A diagnostic predictor model for indeterminate or suspicious thyroid FNA samples.
- Identification of genes differentially expressed in benign versus malignant thyroid tumors.
- Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
- A six-gene model for differentiating benign from malignant thyroid tumors on the basis of gene expression.
- BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
- Quantitative assessment of promoter methylation profiles in thyroid neoplasms.
- Modern approaches to age-old questions about thyroid tumors.
- Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.
- Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules.
- Using gene expression profiling to differentiate benign versus malignant thyroid tumors.
- Beyond the suspicious thyroid fine needle aspirate. A review.
- Molecular pathogenesis of thyroid cancer.
- Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
- Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR.
- Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation.
- High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
- High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor.
- Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
- Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms.
- Telomerase activity as a measure for monitoring radiocurability of tumor cells.
- Applications of telomerase research in the fight against cancer.
- Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1. Its potential role in chromosomal instability.
- Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers.
- Telomerase activity in the normal and neoplastic rat mammary gland.
- Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.
- Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
- Recombinant replication protein A: expression, complex formation, and functional characterization.
- High-resolution genomic mapping of the three human replication protein A genes (RPA1, RPA2, and RPA3).
- Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A.
- Initiation of SV40 DNA replication: mechanism and control.
- Do breast cancer cell lines provide a relevant model of the patient tumor methylome?
- Telomerase activity and prognosis in primary breast cancers.
- Evaluation of shape descriptors for the morphometric analysis of cell nuclei.
- Prognostic significance (relapse, non-relapse) of nuclear shape parameters in lymph node negative breast cancer.
- Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer.
- DNA methylation-related vitamin D receptor insensitivity in breast cancer.
- Evaluation for concomitant thyroid nodules and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomy.
- Computerized image analysis of nuclear shape as a prognostic factor for prostatic cancer.
Doctors Specialties
- Internal Medicine
Accepted Insurances
Education
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Johns Hopkins University -
University of Basel Faculty of Medicine
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