Director, Yale OCD Research Clinic Assistant Professor of Psychiatry Yale University
Psychiatry
Dr. Christopher J. Pittenger, MD
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Doctor Christopher J. Pittenger, MD works in the field of Psychiatry. He attended Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a top medical university. Columbia University College of Physicians & Surgeons is ranked 8 in research and 52 in primary care medicine Christopher Pittenger is a published doctor. He published 69 publications, including: 'A genetic switch for long-term memory.'
Publications
- Arbitration between Action Strategies in Obsessive-Compulsive Disorder.
- Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome.
- Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
- Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome.
- Pharmacological Treatment of Obsessive-Compulsive Disorder.
- Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive-compulsive disorder.
- Altered global brain signal in schizophrenia.
- Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.
- Disorders of memory and plasticity in psychiatric disease.
- Partitioning the heritability of tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
- Long-term outcome in adults with obsessive-compulsive disorder.
- Genome-wide association study of obsessive-compulsive disorder.
- Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depre...
- N-acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial.
- Age and gender correlates of pulling in pediatric trichotillomania.
- Striatum-dependent habits are insensitive to both increases and decreases in reinforcer value in mice.
- The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications.
- Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive Disorder.
- Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity.
- Resting state functional connectivity predicts neurofeedback response.
- Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.
- CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects.
- In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus.
- [Past and future studies of memory].
- A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing.
- Toward a neurobiology of psychotherapy: basic science and clinical applications.
- Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.
- N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder.
- Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder.
- Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder.
- Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.
- Visual hallucinations from the addition of riluzole to memantine and bupropion.
- Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors.
- Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania.
- Gabapentin abuse, and delirium tremens upon gabapentin withdrawal.
- The NMDA receptor as a therapeutic target in major depressive disorder.
- Systematic review: pharmacological and behavioral treatment for trichotillomania.
- Stress, depression, and neuroplasticity: a convergence of mechanisms.
- Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review.
- Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a series of 13 cases, with long-term follow-up.
- Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology.
- Riluzole in the treatment of mood and anxiety disorders.
- Meta-analysis of the symptom structure of obsessive-compulsive disorder.
- A double dissociation revealing bidirectional competition between striatum and hippocampus during learning.
- Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder.
- Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse.
- Cued and spatial learning in the water maze: equivalent learning in male and female mice.
- Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.
- Dissociable regulation of instrumental action within mouse prefrontal cortex.
- Clinical treatment of obsessive compulsive disorder.
- Recent advances in Tourette syndrome.
- Epigenetic modification of the BDNF locus by early-life enrichment: towards a molecular correlate of resilience?
- High levels of histidine decarboxylase in the striatum of mice and rats.
- Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder.
- Dimensional correlates of poor insight in obsessive-compulsive disorder.
- Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment.
- Pathophysiological modeling of obsessive-compulsive disorder: challenges, and progress.
- Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety.
- Lesions of the dorsomedial striatum disrupt prepulse inhibition.
- Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene.
- Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes.
- A genetic switch for long-term memory.
- The past, the future and the biology of memory storage.
- Communicating with our elderly.
- Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase.
- Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder.
- Microglial dysregulation in psychiatric disease.
- Lesions of the dorsomedial striatum delay spatial learning and render cue-based navigation inflexible in a water maze task in mice.
Schools
Columbia University College of Physicians And Surgeons
Yale University
Doctors Specialties
- Psychiatry
Accepted Insurances
Education
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Yale-New Haven Hospital -
Columbia University College of Physicians & Surgeons
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