Professor, Anesthesia and Perioperative Care, UCSF School of Medicine

Anesthesiology

Claire Brett works in the field of Anesthesiology. She attended University of Miami Miller School of Medicine. University of Miami Miller School of Medicine is ranked 45 in research and 0 in primary care medicine Dr. Claire M. Brett has written publications. She has 32 publications published with PubMed. The lastest publication is: 'From the cholinergic gene locus to the cholinergic neuron.'

Publications

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• The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers.
• Genetic Variants in Transcription Factors Associate with the Pharmacokinetics and Pharmacodynamics of Metformin.
• Reduced renal clearance of cefotaxime in asians with a low-frequency polymorphism of OAT3 (SLC22A8).
• The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.
• Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.
• Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
• Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5).
• Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.
• The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.
• PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters.
• Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).
• From the cholinergic gene locus to the cholinergic neuron.
• Isolated renal brush border and basolateral membrane vesicles and cultured renal cells.
• Chemical, enzymatic, and human enantioselective S-oxygenation of cimetidine.
• Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides.
• Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney.
• Characterization of a sodium-dependent taurine transporter in rabbit choroid plexus.
• Na+-dependent gamma-aminobutyric acid (GABA) transport in the choroid plexus of rabbit.
• Taurine transport in cultured choroid plexus.
• Nucleoside transport in brush border membrane vesicles from human kidney.
• Primary cell culture of the rabbit choroid plexus: an experimental system to investigate membrane transport.
• Nucleoside transport in isolated human and rhesus choroid plexus tissue slices.
• The pharmacogenetics research network: from SNP discovery to clinical drug response.
• Methods of study drug transport in isolated choroid plexus tissue and cultured cells.
• Saturable disposition of taurine in the rat cerebrospinal fluid.
• Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).
• No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects.
• The effect of N-ethylmaleimide on the Na(+)-dependent nucleoside transporter (N3) in rabbit choroid plexus.
• Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin.
• Role of organic cation transporters in drug absorption and elimination.
• Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics.

Schools

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• University of Miami School of Medicine

• San Francisco General Hospital

• Mt Zion

• University Calif

Doctors Specialties

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• Neonatal Medicine
• Pediatric Critical Care Medicine
• Anesthesiology

Accepted Insurances

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Education

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• UCSF
• University of Miami Miller School of Medicine

Hospital

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• UCSF Medical Center

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