Professor, Pediatrics, University of Minnesota Medical School
Pediatric Nephrology
Dr. Clifford E. Kashtan, MD
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Dr. Clifford E. Kashtan practices Pediatric Nephrology. He went to Wayne State University School of Medicine. Wayne State University School of Medicine is ranked 63/85 in Research/PrimaryCare. He received 2 awards: "America's Top Doctors" and "Super Doctor". Clifford Kashtan is a published doctor and has 100 publications published. The lastest was: 'Structure of the gene for congenital nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations.'
Publications
- Quaternary Epitopes of ?345(IV) Collagen Initiate Alport Post-Transplant Anti-GBM Nephritis.
- Clinical practice recommendations for the treatment of Alport Syndrome: a statement of the Alport Syndrome Research Collaborative.
- Improved Survival over the Last Decade in Pediatric Patients Requiring Dialysis after Hematopoietic Cell Transplantation.
- Reversible Fanconi Syndrome in a pediatric patient on deferasirox.
- Alport alloantibodies but not Goodpasture autoantibodies induce murine Glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collag...
- Treatment of Alport Syndrome: beyond animal models.
- The wages of thin.
- Day-to-Day variation of the urine protein: creatinine ratio in female dogs with stable glomerular proteinuria caused by X-linked hereditary nephropathy.
- Genetic cause of autosomal recessive hereditary nephropathy in the English Cocker Spaniel.
- The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 do...
- Gene expression analysis in a canine model of X-linked Alport Syndrome.
- Distribution of type IV collagen in the cochlea in Alport Syndrome.
- The nongenetic diagnosis of thin basement membrane nephropathy.
- Temporal bone histopathology in alport Syndrome.
- Diagnosis of Alport Syndrome.
- Mouse model of X-linked Alport Syndrome.
- Familial hematuria due to type IV collagen mutations: Alport Syndrome and thin basement membrane nephropathy.
- Diet modulates proteinuria in heterozygous female dogs with X-linked hereditary nephropathy.
- Genetic cause of X-linked Alport Syndrome in a family of domestic dogs.
- Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport Syndrome (XLAS).
- Gene mapping in Alport families with different basement membrane antigenic phenotypes.
- Dense intramembranous deposit Disease: a clinical comparison of histological subtypes.
- Hypogammaglobulinemia in uremic infants receiving peritoneal dialysis.
- Should women who are known or potential carriers of the Alport gene be accepted as Kidney donors?
- Long-term quality of life after Kidney transplantation in childhood.
- Transplanted children with long-term graft function have an excellent quality of life.
- Immunochemical studies of the Alport antigen.
- Distribution of the alpha 1 and alpha 2 chains of collagen IV and of collagens V and VI in Alport Syndrome.
- Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash Syndrome.
- High-density genetic and physical mapping of DNA markers near the X-linked Alport Syndrome locus: definition and use of flanking polymorphic markers.
- X-linked Alport Syndrome in females.
- Alport Syndrome, mental retardation, midface hypoplasia, and elliptocytosis: a new X linked contiguous gene deletion Syndrome?
- Alport Syndrome and mental retardation: clinical and genetic dissection of the contiguous gene deletion Syndrome in Xq22.3 (ATS-MR).
- AntiHypertensive drug therapy with captopril in children and adolescents.
- Identification of variant Alport phenotypes using an Alport-specific antibody probe.
- Animal models of Alport Syndrome.
- Autotopes and allotopes.
- Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulat...
- Dysregulation of Renal MMP-3 and MMP-7 in canine X-linked Alport syndrome.
- Familial hematurias: what we know and what we don''t.
- Genetic Disorders of glomerular basement membranes.
- Stem cell therapy for Alport Syndrome: the hope beyond the hype.
- Women with Alport syndrome: risks and rewards of Kidney donation.
- X-inactivation modifies Disease severity in female carriers of murine X-linked Alport syndrome.
- Risk factors and treatment success for ureteral obstruction after pediatric Renal transplantation.
- The effect of progressive glomerular disease on megalin-mediated endocytosis in the Kidney.
- Aortic abnormalities in males with Alport Syndrome.
- Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
- Alport Syndrome and Thin Basement Membrane Nephropathy: Diseases Arising from Mutations in Type IV Collagen.
- Familial hematuria.
- Alport Syndrome and the X chromosome: implications of a diagnosis of Alport Syndrome in females.
- Renal transplantation in patients with Alport syndrome.
- Glomerular basement membrane disorders in experimental models for renal Diseases: impact on understanding pathogenesis and improving diagnosis.
- Angiotensin converting enzyme inhibitor therapy in children with Alport Syndrome: effect on urinary albumin, TGF-beta, and nitrite excretion.
- Nephritogenic antigen determinants in epidermal and Renal basement membranes of kindreds with Alport-type familial nephritis.
- Long-term follow-up of patients with steroid-dependent, minimal change Nephrotic syndrome.
- Targets of alloantibodies in Alport anti-glomerular basement membrane disease after Renal transplantation.
- Recurrence of Disease in patients retransplanted for focal segmental glomerulosclerosis.
- Renal transplantation in the first year of life: the treatment of choice for infants with end-stage Renal disease.
- Pediatric Renal transplants--results with sequential immunosuppression.
- Successful Kidney transplantation in infants.
- Distribution of familial nephritis antigen in normal tissue and Renal basement membranes of patients with homozygous and heterozygous Alport familial nephritis. Relati...
- Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in Kidneys from X-linked Alport s...
- The genetic basis of pediatric Renal disease.
- The importance of early cyclosporine levels in pediatric Kidney transplantation.
- Identification of two alternatively spliced forms of human tubulointerstitial nephritis antigen (TIN-Ag).
- Alport Syndromes: phenotypic heterogeneity of progressive hereditary nephritis.
- Alport Syndrome: abnormalities of type IV collagen genes and proteins.
- Alport syndrome: Renal transplantation and donor selection.
- Abnormal glomerular basement membrane laminins in murine, canine, and human Alport Syndrome: aberrant laminin alpha2 deposition is species independent.
- Puromycin aminonucleoside suppresses integrin expression in cultured glomerular epithelial cells.
- Familial hematuric syndromes--Alport syndrome, thin glomerular basement membrane Disease and Fechtner/Epstein syndromes.
- Alport Syndrome.
- Recurrence of haemolytic-uraemic syndrome in Renal transplants: a single-centre report.
- Central role of the transcription factor nuclear factor-kappa B in mesangial cell production of chemokines.
- Simultaneous pancreas-Kidney transplant in two children with hemolytic-uremic syndrome.
- Human factor H Deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism.
- Outcome of chickenpox in 66 pediatric Renal transplant recipients.
- Charcoal hemoperfusion in a child with vancomycin overdose and chronic renal Failure.
- Chronology of Renal scarring in males with Alport syndrome.
- Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital Nephrotic syndrome.
- Alport syndrome and thin glomerular basement membrane Disease.
- A model of autosomal recessive Alport Syndrome in English cocker spaniel dogs.
- Expression of mRNA for type IV collagen alpha1, alpha5 and alpha6 chains by cultured dermal fibroblasts from patients with X-linked Alport Syndrome.
- Hemodialysis catheter placement and recirculation in treatment of hyperammonemia.
- Structure of the gene for congenital Nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations.
- Aortic dissection in young patients with Chronic hypertension.
- New form of X-linked dominant hereditary nephritis in dogs.
- Alport Syndrome: is diagnosis only skin-deep?
- The central role of nuclear factor-kappa B in mesangial cell activation.
- Glomerular Disease.
- Alport syndrome. An inherited disorder of Renal, ocular, and cochlear basement membranes.
- Recurrent bacteremia with enteric pathogens in recessive polycystic Kidney disease.
- Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as part of Renal-coloboma syndrome.
- Expression of the alpha6 chain of type IV collagen in glomerular basement membranes of healthy adult dogs.
- Kidney transplantation in the absence of the infrarenal vena cava.
- Inherited factor H Deficiency and collagen type III glomerulopathy.
- Structural-functional relationships in Alport Syndrome.
- Autosomal recessive Alport Syndrome: mutation in the COL4A3 gene in a woman with Alport Syndrome and posttransplant antiglomerular basement membrane nephritis.
Schools
Wayne State University School Of Medicine
Boston City Hospital
Mass Genl Hospital University Minn
Procedures Preformed
- Hemodialysis
Conditions Treated
- Acidosis
- Acute Kidney Failure
- Chronic Glomerulonephritis
- Chronic Kidney Diseases
- View All
Doctors Specialties
- Pediatric Nephrology
Accepted Insurances
Awards
- America's Top Doctors
- Super Doctor
Education
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University of Minnesota at Fairview -
Massachusetts General Hospital -
Boston University Medical Center -
Wayne State University School of Medicine
Hospital
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University of Minnesota Medical Center, Fairview
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