Professor, Pediatrics, Medical College of Wisconsin

Neonat/Perinatology

Dr. D G. McCarver, MD

Dr. D G. McCarver works in the field of Neonat/Perinatology. She attended Indiana University School of Medicine. Indiana University School of Medicine is ranked 45/47 in Research/PrimaryCare. McCarver is also published. She has 30 publications published. The lastest publication: "Knowledge and misconceptions among inner-city African-American mothers regarding alcohol and drug use.'

Publications

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.
Human Hepatic UGT2B15 Developmental Expression.
Identification and functional analysis of a novel human CYP2E1 far upstream enhancer.
The effect of CYP2D6 polymorphisms on the response to pain treatment for pediatric sickle cell pain crisis.
Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
Pharmacogenomics and the future of drug therapy.
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.
Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.
Proximity of residence to trichloroethylene-emitting sites and increased risk of offspring congenital heart defects among older women.
Alcohol dehydrogenase 2*3 affects alterations in offspring facial morphology associated with maternal ethanol intake in pregnancy.
Applicability of the principles of developmental pharmacology to the study of environmental toxicants.
Excess birth prevalence of Hypoplastic Left Heart syndrome in eastern Wisconsin for birth cohorts 1997-1999.
Developmental expression of human hepatic CYP2C9 and CYP2C19.
Human hepatic CYP2E1 expression during development.
Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6).
Completeness of state administrative databases for surveillance of congenital heart disease.
Trichloroethylene decreases heat shock protein 90 interactions with endothelial nitric oxide synthase: implications for endothelial cell proliferation.
Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis.
The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes.
The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms.
ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects.
Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans.
Development of dapsone toxicity in patients with inflammatory dermatoses: activity of acetylation and hydroxylation of dapsone as risk factors.
Knowledge and misconceptions among inner-city African-American mothers regarding alcohol and drug use.
A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake.
Alcohol dehydrogenase-2*3 allele protects against alcohol-related birth defects among African Americans.
Genetic polymorphisms in human drug metabolic enzymes.
Ethnic differences in allelic frequency of two flavin-containing monooxygenase 3 (FMO3) polymorphisms: linkage and effects on in vivo and in vitro FMO activities.
Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model.

Schools

University of Tennessee Memphis College of Medicine amp Surgery
Clarian Indiana University Hospital

Doctors Specialties

Neonatal Medicine
Neonat/Perinatology

Accepted Insurances

Education

Vanderbilt University
Indiana University School of Medicine
University of Tennessee College of Medicine

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