Professor of Anesthesiology and Critical Care Medicine, Associate Professor of Surgery, Johns Hopkins University School of Medicine; Director of Cardiac Anesthesia Division, Executive Vice Chairman, ACCM, The Johns Hopkins University School of Medicine
Anesthesiology
Dr. Daniel Nyhan, MD
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Dr. Daniel Nyhan works in the field of Anesthesiology. He received 2 awards: "Super Doctor" and "Top MD". Daniel Nyhan is a published doctor and has 67 publications published. The lastest was: 'Effect of hypoxia on respiratory system impedance in dogs.' He accepts all Medicare patients.
Publications
- Role of senescence marker p16(INK4a) measured in peripheral blood T-lymphocytes in predicting length of hospital stay after coronary artery bypass surgery in older adu...
- Seeking a blood pressure-independent measure of vascular properties.
- Hypertrophic cardiomyopathy: a review.
- Melanopsin mediates light-dependent relaxation in blood vessels.
- Cataract surgery in patients with left ventricular assist device support.
- Contribution of arginase activation to vascular dysfunction in cigarette smoking.
- New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease.
- Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.
- Nitric oxide regulates tissue transglutaminase localization and function in the vasculature.
- Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction.
- Vascular stiffness and increased pulse pressure in the aging cardiovascular system.
- Review article: implications of vascular aging.
- β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.
- Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway.
- Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.
- Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta.
- Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
- Simulated microgravity-induced aortic remodeling.
- Perioperative blood pressure management: does central vascular stiffness matter?
- Arginase and vascular aging.
- Endothelial arginase II: a novel target for the treatment of atherosclerosis.
- Physiology of pulmonary circulation and its relevance to the cardiac anaesthetist.
- Mitochondrial arginase II constrains endothelial NOS-3 activity.
- Pulse pressure is an age-independent predictor of stroke development after cardiac surgery.
- Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction.
- Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness.
- Microgravity-induced changes in aortic stiffness and their role in orthostatic intolerance.
- Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling.
- Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.
- Knockdown of arginase I restores NO signaling in the vasculature of old rats.
- Increased cross-bridge cycling rate in stunned myocardium.
- Simulated microgravity produces attenuated baroreflex-mediated pressor, chronotropic, and inotropic responses in mice.
- Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction.
- Enhanced vasodilatory responses to milrinone in catecholamine-precontracted small pulmonary arteries.
- Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
- Impaired pulmonary artery contractile responses in a rat model of microgravity: role of nitric oxide.
- Effect of hypoxia on respiratory system impedance in dogs.
- Selective endothelial dysfunction in conscious dogs after cardiopulmonary bypass.
- Single doses of intravenous protamine result in the formation of protamine-specific IgE and IgG antibodies.
- Amrinone and the pulmonary vascular pressure-flow relationship in conscious control dogs and following left lung autotransplantation.
- Abnormal responses to pulmonary vasodilators in conscious dogs after left lung autotransplantation.
- Pulmonary vascular beta-adrenoreceptor activity in conscious dogs after left lung autotransplantation.
- Pulmonary vascular alpha 1-adrenoreceptor activity in conscious dogs after left lung autotransplantation.
- Humoral pulmonary vasoregulation in conscious dogs after left lung autotransplantation.
- Pulmonary vasoregulation by arginine vasopressin in conscious, halothane-anesthetized, and pentobarbital-anesthetized dogs with increased vasomotor tone.
- Neurohumoral regulation of the pulmonary circulation during circulatory hypotension in conscious dogs.
- Prolonged pulmonary vascular hyperreactivity in conscious dogs after cardiopulmonary bypass.
- Thoracotomy increases peripheral airway tone and reactivity.
- Bradykinin actively modulates pulmonary vascular pressure-cardiac index relationships.
- Pulmonary vascular responses to angiotensin II and captopril in conscious dogs.
- Pulmonary vasoactive effects of exogenous and endogenous AVP in conscious dogs.
- Pentobarbital anesthesia modifies pulmonary vasoregulation after hypoperfusion.
- Autonomic nervous system pulmonary vasoregulation after hypoperfusion in conscious dogs.
- AVP-induced pulmonary vasodilation during specific V1 receptor block in conscious dogs.
- Combined neurohumoral block modulates pulmonary vascular P/Q relationship in conscious dogs.
- Pentobarbital anesthesia alters pulmonary vascular response to neural antagonists.
- Pentobarbital augments pulmonary vasoconstrictor response to cyclooxygenase inhibition.
- Halothane alters the oxygen consumption-oxygen delivery relationship compared with conscious state.
- Halothane anesthesia causes active flow-independent pulmonary vasoconstriction.
- Pulmonary vasoregulation by cyclooxygenase metabolites and angiotensin II after hypoperfusion in conscious, pentobarbital-anesthetized, and halothane-anesthetized dogs.
- Hemodynamic effects and onset time of increasing doses of vecuronium in patients undergoing myocardial revascularization.
- N omega-nitro-L-arginine and pulmonary vascular pressure-flow relationship in conscious dogs.
- Anesthesia alters pulmonary vasoregulation by angiotensin II and captopril.
- Acute and chronic pulmonary vasoconstriction after left lung autotransplantation in conscious dogs.
- Halothane anesthesia abolishes pulmonary vascular responses to neural antagonists.
- Differential effects of general anesthesia on cGMP-mediated pulmonary vasodilation.
Schools
University College of Cork National University of Ireland
Reg Hospital
Johns Hopkins
Regl Hospital
Doctors Specialties
- Anesthesiology
Accepted Insurances
Awards
- Super Doctor
- Top MD
Education
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Johns Hopkins University -
University College Cork Faculty of Medicine
Hospital
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Johns Hopkins Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1972543510 |
| Last Name Of The Provider | NYHAN |
| First Name Of The Provider | DANIEL |
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