Professor, Internal Medicine, Washington University School of Medicine
Cardiology
Dr. Daniel S. Ory, MD
Daniel S. Ory works in the field of Cardiology. He graduated from Harvard Medical School. Harvard Medical School is a top medical university. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He has 1 awards "Elected Member". Daniel is a published physician. He published 52 publications, including: 'A Diet Rich in Medium-Chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients With Type 2 Diabetes: A Pilot Study.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- RNASET2 is required for ROS propagation during oxidative stress-mediated cell death.
- A Diet Rich in Medium-Chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients With Type 2 Diabetes: A Pilot Study.
- A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol.
- Intrathecal 2-hydroxypropyl-beta-cyclodextrin in a single patient with Niemann-Pick C1.
- High incidence of unrecognized visceral/neurological late-onset Niemann-Pick Disease, type C1, predicted by analysis of massively parallel sequencing data sets.
- Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) is Dynamically Regulated by NADPH Oxidase.
- Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 Disease.
- Plasma Sphingolipids Associated with COPD Phenotypes.
- Cholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative Disease Niemann-Pick C1 (NPC1).
- Development and validation of sensitive LC-MS/MS assays for quantification of 2-hydroxypropyl-β-cyclodextrin in human plasma and CSF.
- Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers.
- Side-Chain Oxysterols Modulate Cholesterol Accessibility through Membrane Remodeling.
- Box C/D snoRNA U60 Regulates Intracellular Cholesterol Trafficking.
- The structural basis of cholesterol accessibility in membranes.
- Psychosine, the cytotoxic sphingolipid that accumulates in Globoid Cell Leukodystrophy, alters membrane architecture.
- Development and validation of LC-MS/MS method for determination of very long acyl chain (C22:0 and C24:0) ceramides in human plasma.
- Identification of Niemann-Pick C1 (NPC1) Disease biomarkers through sphingolipid profiling.
- Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick Disease, type C1.
- Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
- Oxysterols as non-genomic regulators of cholesterol homeostasis.
- Lysosomal acid lipase deficiency impairs regulation of ABCA1 and formation of high density lipoproteins in Cholesteryl Ester Storage Disease.
- Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress.
- Side-chain oxysterols: From cells to membranes to molecules.
- A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 Disease from human plasma.
- Synthesis of the enantiomer of the oxysterol-antagonist LY295427.
- 25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes.
- Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 Disease.
- ApoA-1 in diabetes: damaged goods.
- miR-33 links SREBP-2 induction to repression of sterol transporters.
- Getting a "Hold" on NPC2.
- The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress.
- Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.
- Chronic cyclodextrin treatment of murine Niemann-Pick C Disease ameliorates neuronal cholesterol and glycosphingolipid storage and Disease progression.
- Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking.
- Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding.
- Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.
- Chylomicrons and lipoprotein lipase at the endothelial surface: bound and GAG-ged?
- Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death.
- Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C Disease.
- A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation.
- Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes.
- A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death.
- The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol.
- Transgenic expression of fatty acid transport protein 1 in the Heart causes lipotoxic cardiomyopathy.
- Nuclear receptor signaling in the control of cholesterol homeostasis: have the orphans found a home?
- The niemann-pick Disease genes; regulators of cellular cholesterol homeostasis.
- The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking.
- NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
- Oligomerization of the murine fatty acid transport protein 1.
- Triglyceride accumulation protects against fatty acid-induced lipotoxicity.
- Neurologic Abnormalities in Mouse Models of the Lysosomal Storage Disorders Mucolipidosis II and Mucolipidosis III γ.
Schools
Harvard Medical School
Brigham and Women39s Hospital
Mass Gen Hospital
Procedures Preformed
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardioverter-Defibrillator or Pacemaker Insertion, Removal or Repair
- Coronary Angioplasty, Atherectomy and Stent
Conditions Treated
- Aneurysm and Dissection of Heart
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Cardiomegaly
- View All
Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Elected Member
Education
-
Massachusetts General Hospital -
Brigham and Women's Hospital -
Harvard Medical School
Hospital
-
Barnes-Jewish Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1164448478 |
| Last Name Of The Provider | ORY |
| First Name Of The Provider | DANIEL |
| View All |
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