Professor, Internal Medicine, Washington University School of Medicine
Gastroenterology
Dr. David H. Alpers, MD
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David Alpers is an expert in the field of Gastroenterology. He researched medicine at Harvard Medical School. Harvard Medical School is a top medical college. Harvard Medical School is ranked 1/12 in Research/PrimaryCare. He has 4 awards "CMS Meaningful Use Stage 1 Certification", "Fellow (AGAF)", "Elected Member" and "Whos Who in Medicine and Healthcare". Doctor David H. Alpers, MD is a published doctor. He published 100 publications, including: 'Development and hormonal modulation of postnatal expression of intestinal alkaline phosphatase mRNA species and their encoded isoenzymes.' David Alpers accepts Medicare payments and is registered with Medicare.gov.
Publications
- The Pharmacodynamics, Safety, and Pharmacokinetics of Single Doses of the Motilin Agonist, Camicinal, in Type 1 Diabetes Mellitus with Slow Gastric Emptying.
- Absorption and blood/cellular transport of folate and cobalamin: pharmacokinetic and physiological considerations.
- Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database.
- Intraluminal bioavailability of divalent cations.
- Gastric intrinsic factor: The gastric and small intestinal stages of cobalamin absorption. A personal journey.
- Novel in vitro model for studying hepatic ischemia-reperfusion injury using liver cubes.
- Subclinical micronutrient deficiency: a problem in recognition.
- Vitamins as drugs: the importance of pharmacokinetics in oral dosing.
- Nutrient sensing in the gastrointestinal tract.
- Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.
- Garlic and its potential for prevention of colorectal cancer and other conditions.
- Irritable bowel syndrome: more than abdominal pain and bowel habit abnormalities.
- The potential use of curcumin in management of chronic disease: too good to be true?
- A novel phosphatase upregulated in Akp3 knockout mice.
- Ray E. Clouse, MD, Washington University gastroenterologist, clinical investigator, and educator.
- Monitoring liver safety in drug development: the GSK experience.
- Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis.
- Vitamins and prevention of cardiovascular disease and cancer: should we give supplements?
- Dietary fiber decreases colonic epithelial cell proliferation and protein synthetic rates in human subjects.
- Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types.
- The effect of hyperglycemic hyperinsulinemia on small-intestinal mucosal protein synthesis in patients after surgical stress.
- Glutamine: do the data support the cause for glutamine supplementation in humans?
- Retinoic acid stimulates the dynamics of mouse gastric epithelial progenitors.
- What is new in vitamin B(12)?
- The presentation of irritable bowel syndrome in the context of somatization disorder.
- Why, how, and to which part of the gastrointestinal tract should forced enteral feedings be delivered in patients?
- Identification of a 4-base deletion in the gene in inherited intrinsic factor deficiency.
- A genetic polymorphism in the coding region of the gastric intrinsic factor gene (GIF) is associated with congenital intrinsic factor deficiency.
- Accelerated fat absorption in intestinal alkaline phosphatase knockout mice.
- Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding.
- Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187.
- Vitamin therapy for metabolic diseases.
- Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells.
- Equilibrium and kinetic analyses of the interactions between vitamin B(12) binding proteins and cobalamins by surface plasmon resonance.
- How adaptable is the intestine in patients with short-bowel syndrome?
- The role of nutritional deficiency in the osteopenia and osteoporosis of gastrointestinal diseases.
- Liver complications and failure in patients on home parenteral nutrition.
- Micellar function.
- Biochemical effects of CCl-4 on rat intestinal mucosa.
- The role of lipid peroxidation in the pathogenesis of carbon tetrachloride-induced liver injury.
- Separation and isolation of rat and human intestinal beta-galactosidases.
- On beta-galactosidase activity.
- The effect of carbon tetrachloride on rat-liver lysosomes.
- Localization of immunoreactive alkaline phosphatase in the rat small intestine at the light microscopic level by immunocytochemistry.
- Hepatobiliary and pancreatic clearance of circulating pancreatic amylase.
- Fate of circulating isoamylases in the rabbit.
- Metabolism of glycosylated human salivary amylase: in vivo plasma clearance by rat hepatic endothelial cells and in vitro receptor mediated pinocytosis by rat macropha...
- Control of thymidine incorporation in mucosal explants from patients with chronic ulcerative colitis.
- Dog intestinal mucosa contains two vitamin D-stimulating calcium binding proteins.
- Isolation and characterization of the ileal receptor for intrinsic factor-cobalamin.
- Interaction of receptor for intrinsic factor-cobalamin complex with synthetic and brush-border lipids.
- Isolation and characterization of proteolytically derived ileal receptor for intrinsic factor-cobalamin.
- The nucleotide sequence of rat liver fatty acid binding protein mRNA.
- Effect of bile and bile acids on binding of intrinsic factor to cobalamin and intrinsic factor-cobalamin complex to ileal receptor.
- Binding of intrinsic factor to ileal brush border membrane in the rat.
- Absorption and transport of cobalamin (vitamin B12).
- Immunocytochemical localization of the intrinsic factor-cobalamin receptor in dog-ileum: distribution of intracellular receptor during cell maturation.
- Functional gastrointestinal disorders.
- Energy sources for total parenteral nutrition patients: would sugar suffice/.
- Metabolism of human isoamylases in the rabbit.
- Quantitation of human intestinal and liver/bone alkaline phosphatase in serum by rocket electroimmunoassay.
- The role of psychiatric assessment in the management of functional bowel disease.
- Hepatic clearance of rat plasma intestinal alkaline phosphatase.
- Cloning of a cDNA encoding rat intestinal fatty acid binding protein.
- A study of the association between Crohn's disease and psychiatric illness.
- Biosynthesis and compartmentalization of rat-intestinal vitamin-D-dependent calcium-binding protein.
- Biosynthesis of apolipoprotein C-III in rat liver and small intestinal mucosa.
- Induction of rat hepatic and intestinal alkaline phosphatase activity produced by bile from bile duct-ligated animals.
- Effect of pancreatic proteases on intestinal lactase activity.
- Turnover of intestinal brush-border proteins during postnatal development in rat.
- Characterization and comparison of soluble and membranous forms of intestinal alkaline phosphatase from the suckling rat.
- Distribution of soluble and membranous forms of alkaline phosphatase in the small intestine of the rat.
- The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein.
- The effects of fat feeding on apolipoprotein AI secretion from rat small intestinal epithelium.
- Surgical therapy for obesity.
- Cloning of a complementary deoxyribonucleic acid encoding a portion of rat intestinal preapolipoprotein AIV messenger ribonucleic acid.
- Noncirrhotic nodular transformation of the liver with portal hypertension: clinical, angiographic, and pathological correlation.
- Effect of secreted Bacteroides proteases on human intestinal brush border hydrolases.
- A controlled study of the association between ulcerative colitis and psychiatric diagnoses.
- Proteolytic processing of the primary translation product of rat intestinal apolipoprotein A-IV mRNA. Comparison with preproapolipoprotein A-I processing.
- Postnatal development of intestinal secretin in rats and guinea pigs.
- Irritable bowel-still more questions than answers.
- Labelling of intestinal brush border membrane proteins in vivo using diazotised[125I]iodosulfanilic acid.
- Effect of intralumenal cation-exchange resin on excretion of ammonia in rat ileum.
- Independent biosynthesis of soluble and membrane-bound alkaline phosphatases in the suckling rat ileum.
- Long-term follow-up of jejunoileal bypass patients.
- Jejunoileal bypass. Late metabolic sequelae and weight gain.
- Current status of surgery for morbid obesity.
- Appearance of surfactant-like particles in apical medium of Caco-2 cells may occur via tight junctions.
- Synthesis and parallel secretion of rat intestinal alkaline phosphatase and a surfactant-like particle protein.
- Two rat intestinal alkaline phosphatase isoforms with different carboxyl-terminal peptides are both membrane-bound by a glycan phosphatidylinositol linkage.
- A review of studies of psychiatric factors in Crohn's disease: etiologic implications.
- Cathepsin L mediates intracellular ileal digestion of gastric intrinsic factor.
- The significance and future prospects of study of the small intestine.
- The secretion of intestinal alkaline phosphatase (IAP) from the enterocyte.
- Zinc and deficiencies of taste and smell.
- Antidepressant therapy in 138 patients with irritable bowel syndrome: a five-year clinical experience.
- Expression of an endogenous asialoglycoprotein receptor in a human intestinal epithelial cell line, Caco-2.
- Development and hormonal modulation of postnatal expression of intestinal alkaline phosphatase mRNA species and their encoded isoenzymes.
Schools
Harvard Medical School
Massachusetts General Hospital
Doctors Specialties
- Internal Medicine
- Gastroenterology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow (AGAF)
- Elected Member
- Whos Who in Medicine and Healthcare
Education
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Massachusetts General Hospital -
Harvard Medical School
Hospital
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Barnes-Jewish Hospital
Drug Facts
| NPI NUMBER | 1740207208 | |
| NPPES Provider LastName | ALPERS | |
| NPPES Provider FirstName | DAVID | |
| NPPES Provider ZIPCode | 631101032 | |
| NPPES Provider State | MO | |
| Specialty Description | Gastroenterology | |
| Total Claim Count | 16.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1740207208 |
| Last Name Of The Provider | ALPERS |
| First Name Of The Provider | DAVID |
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