Professor, Medicine, UCSF School of Medicine
Internal Medicine
Dr. David J. Erle, MD
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David J. Erle, MD practices Internal Medicine. He went to University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is a top medical college. University of California San Francisco School of Medicine is ranked 3 in research and 3 in primary care medicine David Erle is a published doctor and has 75 publications published. The lastest was: 'Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) ...' David Erle accepts Medicare payments and is listed with Medicare.gov.
Publications
- The ER resident protein AGR3 is required for regulation of ciliary beat frequency in the airway.
- Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.
- IL-17 and "TH2-high" Asthma: Adding fuel to the fire?
- The cell biology of Asthma.
- Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease.
- Massively parallel functional annotation of 3' untranslated regions.
- The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.
- Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-?1.
- T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.
- An integrated nano-scale approach to profile miRNAs in limited clinical samples.
- Airway Epithelial miRNA Expression is Altered in Asthma.
- The ?v?6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.
- The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.
- Toward a systematic understanding of mRNA 3' untranslated regions.
- Airway Epithelial miRNA Expression in Asthma.
- An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors.
- Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic Asthma.
- Systemically dispersed innate IL-13-expressing cells in type 2 immunity.
- Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.
- Distinct roles of FOXA2 and FOXA3 in allergic airway disease and Asthma.
- The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.
- Thymic OX40 expression discriminates cells undergoing strong responses to selection ligands.
- CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation.
- Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking.
- The epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammat...
- Disease-specific gene expression profiling in multiple models of lung Disease.
- Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1.
- Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.
- Genome-wide profiling identifies epithelial cell genes associated with Asthma and with treatment response to corticosteroids.
- Progress toward a systems biology approach to acute lung injury.
- Genomics and proteomics of lung Disease: conference summary.
- IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production.
- Influenza virus infection causes global Respiratory tract B cell response modulation via innate immune signals.
- The Asthma channel? Stay tuned . . .
- A distinctive alveolar macrophage activation state induced by cigarette smoking.
- IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production.
- Dissecting Asthma using focused transgenic modeling and functional genomics.
- Abnormal alveolar development associated with elevated adenine nucleosides.
- Spotted long oligonucleotide arrays for human gene expression analysis.
- Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in Asthma.
- Use of spotted oligonucleotide arrays for large-scale analysis of mammalian gene expression.
- The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.
- Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering.
- Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient Kit(W-sh)/Kit(W-sh) sash mice.
- Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types.
- Preferential production of interferon-gamma by CD4+ T cells expressing the homing receptor integrin alpha4/beta7.
- Effect of serial-day exposure to nitrogen dioxide on airway and blood leukocytes and lymphocyte subsets.
- Intraepithelial lymphocytes in the lung: a neglected lymphocyte population.
- Recent advances in molecular biological techniques and their relevance to Pulmonary research.
- Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) ...
- Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.
- Presentation of integrins on leukocyte microvilli: a role for the extracellular domain in determining membrane localization.
- Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1.
- Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.
- Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph.
- Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.
- Characterization of the leukocyte integrin subunit beta 7.
- Intraepithelial lymphocytes. Scratching the surface.
- Polymerase chain reaction cloning with degenerate primers: homology-based identification of adhesion molecules.
- Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.
- Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes.
- Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression.
- Effect of exercise rate and route of inhalation on sulfur-dioxide-induced bronchoconstriction in Asthmatic subjects.
- Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.
- Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes.
- Novel integrin alpha and beta subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction.
- How do integrins integrate? The role of cell adhesion receptors in differentiation and development.
- Identification of novel airway epithelial integrins using the homology-based polymerase chain reaction.
- Activated alpha4 integrins are preferentially expressed on immature thymocytes and activated T cells.
- Increased DNA microarray hybridization specificity using sscDNA targets.
- Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2.
- Differential gene expression by integrin beta 7+ and beta 7- memory T helper cells.
- Asthma investigators begin to reap the fruits of genomics.
- MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.
Schools
University of California At San Francisco
Moffitt Hospital University Of Ca
University Ca Sf School Of Med
Procedures Preformed
- Bronchoscopy
- Thoracentesis
- Ventilation Management
Conditions Treated
- Acidosis
- Asthma
- Atelectasis
- COPD (Chronic Obstructive Pulmonary Disease)
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Doctors Specialties
- Pulmonology
- Internal Medicine
Accepted Insurances
Education
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UCSF -
University of California San Francisco School of Medicine
Hospital
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San Francisco General Hospital and Trauma Center -
UCSF Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1770599920 |
| Last Name Of The Provider | ERLE |
| First Name Of The Provider | DAVID |
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