Professor of Medicine, Boston University
Pulmonology
Dr. David M. Center, MD
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Doctor David M. Center, MD works in the field of Pulmonology. He went to medical school at Boston University School of Medicine. Boston University School of Medicine has a rank of 30 in research and a 52 in primary care He received awards:"Regional Top Doctor", "Elected Member" and "Super Doctor". David M. Center is a published physician. He has 100 papers published. The most current publication "Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis." He accepts Medicare payments and is listed with Medicare.gov.
Publications
- In memoriam: dr. Gordon L. Snider.
- Regulation of cellular processes by interleukin-16 in homeostasis and Cancer.
- Genomic Medicine and Lung Diseases: NHLBI Workshop.
- Loss of nuclear pro-IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma.
- A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.
- Human immunodeficiency virus type 1 gp120 reprogramming of CD4+ T-cell migration provides a mechanism for lymphadenopathy.
- Pro-IL-16 recruits histone deacetylase 3 to the Skp2 core promoter through interaction with transcription factor GABP.
- Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits Allergic asthma in a murine model.
- Taking the "idio" out of idiopathic Pulmonary fibrosis: a call to arms.
- Chemokine receptor CXCR3 desensitization by IL-16/CD4 signaling is dependent on CCR5 and intact membrane cholesterol.
- Association of Asthma with a functional promoter polymorphism in the IL16 gene.
- Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes.
- Nuclear pro-IL-16 regulation of T cell proliferation: p27(KIP1)-dependent G0/G1 arrest mediated by inhibition of Skp2 transcription.
- Cutting edge: IL-16/CD4 preferentially induces Th1 cell migration: requirement of CCR5.
- Induced sputum analysis for T helper type 2 cell regulation: closing the loop.
- Tumor necrosis factor-alpha-induced synthesis of interleukin-16 in airway epithelial cells: priming for serotonin stimulation.
- Immunomodulatory effect of interleukin-16 on Allergic airway inflammation.
- Binding of HTLV-1 tax oncoprotein to the precursor of interleukin-16, a T cell PDZ domain-containing protein.
- Prointerleukin-16 contains a functional CcN motif that regulates nuclear localization.
- Differential roles of IL-16 and CD28/B7 costimulation in the generation of T-lymphocyte chemotactic activity in the bronchial mucosa of mild and moderate Asthmatic ind...
- Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.
- IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling.
- Bovine and human endothelial cell production of neutrophil chemoattractant activity in response to components of the angiotensin system.
- Interstitial Pulmonary fibrosis induced in hamsters by intratracheally administered chrysotile asbestos. Histology, lung mechanics, and inflammatory events.
- Identification of chemoattractant activity for lymphocytes in bullous pemphigoid bullous fluid.
- Alteration of rat splenic lymphocyte migration in vitro by the state of microtubule integrity.
- In vitro corticosteroid modulation of lymphocyte migration.
- When should inhaled corticosteroids be started for Asthma?
- Identification of rat mast cell--derived chemoattractant factors for lymphocytes.
- Cold urticaria. Recognition and characterization of a neutrophil chemotactic factor which appears in serum during experimental cold challenge.
- The relevance of neutrophil chemotactic factors to Allergic disease.
- Percutaneous coronary atherectomy: a preliminary report.
- Influence of ethanol on human T-lymphocyte migration.
- Identification and characterization of neutrophil chemotactic activity in aspirin-induced Asthma.
- Effect of ambient oxygen on cultured endothelial cells from different vascular beds.
- Components of the angiotensin system cause release of a neutrophil chemoattractant from cultured bovine and human endothelial cells.
- Phenotype of IL-16-producing cells in bronchial mucosa: evidence for the human eosinophil and mast cell as cellular sources of IL-16 in Asthma.
- A proposed model for the accumulation of helper/inducer lymphocytes in Sarcoidosis. The role of lymphocyte subset-specific chemoattractant lymphokines.
- Biological activity of interleukin-16.
- Modulation of lymphocyte migration by human lymphokines. II. Purification of a lymphotactic factor (LCF).
- Modulation of lymphocyte migration by human lymphokines. III. Characterization of a lymphocyte migration inhibitory factor (LyMIF35K).
- Chemotactic activity of porcine insulin for human T lymphocytes in vitro.
- Expression of IL-16 in allergen-induced late-phase nasal responses and relation to topical glucocorticosteroid treatment.
- Generation of, lipid neutrophil chemoattractant activity by histamine-stimulated cultured endothelial cells.
- Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in Atopic dermatitis.
- Lymphocyte recruitment to the Lung.
- Modulation of lymphocyte migration by human lymphokines. I. Identification and characterization of chemoattractant activity for lymphocytes from mitogen-stimulated mon...
- IL-16 anti-HIV-1 therapy.
- A human T-T-cell hybridoma-derived lymphocyte chemoattractant factor.
- Role of IL-16 in HIV replication.
- Induction of human monocyte motility by lysyl oxidase.
- Lymphocyte motility and lymphocyte chemoattractant factors.
- Lymphokine activation of T4+ T lymphocytes and monocytes.
- The lymphocyte chemoattractant factor.
- Lymphocyte activation by HIV-1 envelope glycoprotein.
- CD4-mediated stimulation of human eosinophils: lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration.
- Biologic activities of HIV-1 envelope glycoprotein: the Effects of crosslinking.
- Interleukin-16.
- Role of the eosinophil in Allergic reactions.
- Structural and functional characterization of the human T lymphocyte receptor for insulin-like growth factor I in vitro.
- Induction of human T lymphocyte motility by interleukin 2.
- Chemoattractant lymphokines specific for the helper/inducer T-lymphocyte subset.
- Human T cell leukemia virus type I (HTLV-I)-specific CD8+ CTL clones from patients with HTLV-I-associated neurologic Disease secrete proinflammatory cytokines, chemoki...
- Functional characteristics of histamine receptor-bearing mononuclear cells. II. Identification and characterization of two histamine-induced human lymphokines that inh...
- CD8+ myelin peptide-specific T cells can chemoattract CD4+ myelin peptide-specific T cells: importance of IFN-inducible protein 10.
- A role for the alveolar epithelium in recruitment of mononuclear cells into the Lung.
- Polarized type 1 cytokine profile in bronchoalveolar lavage T cells of patients with hypersensitivity pneumonitis.
- Functional characteristics of histamine receptor-bearing mononuclear cells. I. Selective production of lymphocyte chemoattractant lymphokines with histamine used as a ...
- Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein-specific CD8+ T cells: potential roles in inflammation.
- Human mast cells produce the CD4+ T lymphocyte chemoattractant factor, IL-16.
- Mechanisms of lymphocyte accumulation in Pulmonary disease.
- Increased expression of interleukin-16 in bronchial mucosa of subjects with atopic Asthma.
- Interleukin 16 and T-cell chemoattractant activity in bronchoalveolar lavage 24 hours after allergen challenge in Asthma.
- Interleukin 16 and its function as a CD4 ligand.
- Increased expression of IL-16 immunoreactivity in bronchial mucosa after segmental allergen challenge in patients with Asthma.
- Signaling and functional properties of interleukin-16.
- Processing and activation of pro-interleukin-16 by caspase-3.
- Cytokine binding to CD4+ inflammatory cells: implications for Asthma.
- Identification of a CD4 domain required for interleukin-16 binding and lymphocyte activation.
- Nuclear translocation of the N-terminal prodomain of interleukin-16.
- Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES.
- Interleukin 16: implications for CD4 functions and HIV-1 progression.
- Human eosinophils release the lymphocyte and eosinophil active cytokines, RANTES and lymphocyte chemoattractant factor.
- Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression.
- The CD4-associated tyrosine kinase p56lck is required for lymphocyte chemoattractant factor-induced T lymphocyte migration.
- Expression of alpha 4 beta 7 integrin on eosinophils and modulation of alpha 4-integrin-mediated eosinophil adhesion via CD4.
- Involvement of IL-16 in the induction of airway hyper-responsiveness and up-regulation of IgE in a murine model of Allergic asthma.
- Evidence for recent as well as long term activation of T cells migrating through endothelial cell monolayers in vitro.
- IL-16 represses HIV-1 promoter activity.
- Cultured human fibroblasts express constitutive IL-16 mRNA: cytokine induction of active IL-16 protein synthesis through a caspase-3-dependent mechanism.
- Early identification of interleukin-16 (lymphocyte chemoattractant factor) and macrophage inflammatory protein 1 alpha (MIP1 alpha) in bronchoalveolar lavage fluid of ...
- Tissue and T cell distribution of precursor and mature IL-16.
- Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged Asthmatic patients.
- Conservation of structure and function between human and murine IL-16.
- Synergistic activation of CD4+ T cells by IL-16 and IL-2.
- IL-16 inhibition of CD3-dependent lymphocyte activation and proliferation.
- Human eosinophils elaborate the lymphocyte chemoattractants. IL-16 (lymphocyte chemoattractant factor) and RANTES.
- CD4 ligand IL-16 inhibits the mixed lymphocyte reaction.
- IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C.
Schools
Boston University School Of Medicine
University Hospital
Boston University
Rb and Pb Brigham Hosps Harva
Procedures Preformed
- Allergy Shots
- Allergy Skin Testing
- Bronchoscopy
Conditions Treated
- Allergic Rhinitis
- Anaphylactic Food Allergies
- Anaphylactic Fruit and Vegetable Allergy
- Anaphylactic Peanut Allergy
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Doctors Specialties
- Pulmonology
Accepted Insurances
Awards
- Regional Top Doctor
- Elected Member
- Super Doctor
Education
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Boston University Medical Center -
Boston University School of Medicine
Hospital
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Boston Medical Center
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