Head, Gastroenterology/Hepatology Division
Gastroenterology
Dr. David M. Hockenbery, MD
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David Hockenbery works in the field of Gastroenterology. He went to medical school at Washington University School of Medicine in St. Louis. He over the years received 1 awards: "Elected Member". David Hockenbery is a published MD. He published 101 publications, including: 'Lymphocytic gastritis resembling graft-vs.-host disease following autologous hematopoietic cell transplantation.' Doctor David M. Hockenbery, MD accepts Medicare.
Publications
- An unsupervised MVA method to compare specific regions in human breast tumor tissue samples using ToF-SIMS.
- The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
- Intracellular Delivery System for Antibody-Peptide Drug Conjugates.
- Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy.
- Fibrosing Cholestatic Hepatitis C After Hematopoietic Cell Transplantation: Report of 3 Fatal Cases.
- α-1-antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.
- A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells.
- Forecast: rough seas for leukemia.
- Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria.
- Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development.
- HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition.
- Reduced cytochrome C is an essential regulator of sustained insulin secretion by pancreatic islets.
- Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host Disease.
- Investigating neoplastic progression of Ulcerative colitis with label-free comparative proteomics.
- Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells.
- Targeting mitochondria for Cancer therapy.
- Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in Response to TLR4 activation.
- Bak to basics of colonocyte renewal.
- The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry.
- Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking.
- 2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.
- A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host Disease.
- Targeted therapies for epithelial Cancers: in vivo efficacy of the BCL-2/BCL-XL inhibitor 2-MeAA.
- Hsp90 inhibition decreases mitochondrial protein turnover.
- MMPs in unusual places.
- Gastrointestinal graft-versus-host Disease in recipients of autologous hematopoietic stem cells: incidence, risk factors, and outcome.
- Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.
- Prevention of Fas-mediated hepatic failure by transferrin.
- Bcl-XL mutations suppress cellular sensitivity to antimycin A.
- BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation.
- Targeting BCL-2-related proteins in Cancer therapy.
- Nailing down a link between tuberin and renal cysts.
- A mitochondrial Achilles' heel in Cancer?
- Mitochondria and apoptosis: new therapeutic targets.
- ToF-SIMS of tissues: "Lessons learned" from mice and women.
- MYC and Mitochondrial Biogenesis.
- Bcl-2 family proteins as regulators of oxidative stress.
- Differential Responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.
- Oral beclomethasone dipropionate in gastrointestinal graft-versus-host Disease.
- Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines.
- Small-molecule inhibitors of Bcl-2.
- Bcl-2-related proteins as drug targets.
- BCL-XL dimerization by three-dimensional domain swapping.
- Preclinical pharmacology of 2-methoxyantimycin A compounds as novel antitumor agents.
- BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.
- Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for Cancer therapy.
- A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve System.
- Identification of androgen-coregulated protein networks from the microsomes of human prostate Cancer cells.
- Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix-induced apoptosis.
- Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A.
- Severe gastroIntestinal bleeding after hematopoietic cell transplantation, 1987-1997: incidence, causes, and outcome.
- Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.
- Caspase-3 and inhibitor of apoptosis protein(s) interactions in Saccharomyces cerevisiae and mammalian cells.
- The role of apoptosis during Intestinal adaptation after small bowel resection.
- Life and death in otolaryngology: mechanisms of apoptosis and its role in the pathology and treatment of Disease.
- Caspase-3 inhibits growth in Saccharomyces cerevisiae without causing cell death.
- Lymphocytic gastritis resembling graft-vs.-host Disease following autologous hematopoietic cell transplantation.
- Bcl-2 slows in vitro breast Cancer growth despite its antiapoptotic effect.
- Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host Disease: a randomized, controlled trial.
- Flow cytometric measurement of mitochondrial mass and function: a novel method for assessing chemoresistance.
- Distinct alterations in mitochondrial mass and function characterize different models of apoptosis.
- Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line.
- Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early Response gene.
- Reactive oxygen species in chick hair cells after gentamicin exposure in vitro.
- Down-regulation of apurinic/apyrimidinic endonuclease expression is associated with the induction of apoptosis in differentiating myeloid leukemia cells.
- BCL-2, a novel regulator of apoptosis.
- Oral beclomethasone dipropionate for treatment of human intestinal graft-versus-host Disease.
- Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis.
- Dysregulated bcl-2 expression inhibits apoptosis but not differentiation of retinoic acid-induced HL-60 granulocytes.
- bcl-2 in Cancer, development and apoptosis.
- Defining apoptosis.
- Bcl-2 protooncogene expression in cervical carcinoma cell lines containing inactive p53.
- bcl-2, a novel regulator of cell death.
- Major histocompatibility complex class II-mediated inhibition of hematopoiesis in long-term marrow cultures involves apoptosis and is prevented by c-kit ligand.
- Primitive human hematopoietic precursors express Bcl-x but not Bcl-2.
- Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
- Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.
- Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.
- Bcl-2: B cell life, death and neoplasia.
- Bcl-2 maintains B cell memory.
- BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
- Immunolocalization of the Bcl-2 protein within hematopoietic Neoplasms.
- bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes.
- Pericrypt eosinophilic enterocolitis and chronic diarrhea.
- The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.
- The bcl-2 oncogene and apoptosis.
- Competitive inhibition of benzodiazepine binding by fractions from porcine brain.
- c-MYC apoptotic function is mediated by NRF-1 target genes.
- Myc's mastery of mitochondrial mischief.
- Highlights of the National Cancer Institute Workshop on mitochondrial function and Cancer.
- Breaking down tumor defenses.
- Efficacy of neodymium:YAG laser therapy for Gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant.
- Bcl-2-related survival proteins.
- Thyroid hormone receptor isoforms localize to cardiac mitochondrial matrix with potential for binding to receptor elements on mtDNA.
- BCL-2 suppresses ceramide-induced cell killing.
- Identification of genes with abnormal expression changes in acute myeloid leukemia.
- c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry.
- Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration.
- Successful medical treatment of Intestinal ulceration caused by Rhizopus microsporus.
- Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry.
Schools
Washington Univ Sch Of Med
Johns Hopkins
BarnesWash University
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
- ERCP (Endoscopic Retrograde Cholangiopancreatography)
Conditions Treated
- Abdominal Pain
- Anemia
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
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Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- Elected Member
Education
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Washington University - Barnes-Jewish Hospital -
Johns Hopkins University -
Washington University School of Medicine in St. Louis
Drug Facts
| NPI NUMBER | 1710199963 | |
| NPPES Provider LastName | HOCKENBERY | |
| NPPES Provider FirstName | DAVID | |
| NPPES Provider ZIPCode | 98109 | |
| NPPES Provider State | WA | |
| Specialty Description | Gastroenterology | |
| Total Claim Count | 24.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1710199963 |
| Last Name Of The Provider | HOCKENBERY |
| First Name Of The Provider | DAVID |
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