Assistant Professor, Internal Medicine, Virginia Tech Carilion School of Medicine

Pulmonology

Deepa Lala works in the field of Pulmonology. She researched medicine at Grant Medical College. Deepa Lala is a published MD as well. She has 22 publications published. The latest was: Function of steroidogenic factor 1 (SF1) ligand-binding domain in gene activation and interaction with AP1.

Publications

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• The human medium chain acyl-CoA dehydrogenase gene promoter consists of a complex arrangement of nuclear receptor response elements and Sp1 binding sites.
• Activation of specific RXR heterodimers by an antagonist of RXR homodimers.
• The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.
• Function of steroidogenic factor 1 (SF1) ligand-binding domain in gene activation and interaction with AP1.
• A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development.
• A cell-specific nuclear receptor regulates the steroid hydroxylases.
• Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.
• Steroidogenic factor-1 binding and transcriptional activity of the cholesterol side-chain cleavage promoter in rat granulosa cells.
• The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis.
• Steroidogenic factor 1 (SF-1) is essential for endocrine development and function.
• An activin receptor-like kinase 5 inhibitor reduces collagen deposition in a rat dermal incision wound healing model.
• The liver X receptors.
• Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone.
• The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.
• Liver X receptors and atherosclerosis.
• Repression of p65 transcriptional activation by the glucocorticoid receptor in the absence of receptor-coactivator interactions.
• Multiplexing nuclear receptors for agonist identification in a cell-based reporter gene high-throughput screen.
• Liver X receptors interact with corepressors to regulate gene expression.
• The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor.
• Steroidogenic factor 1: an essential mediator of endocrine development.
• Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism.

Conditions Treated

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• COPD (Chronic Obstructive Pulmonary Disease)
• Lung Cancer
• Pulmonary Embolism
• Pulmonary Hypertension
• View All

Doctors Specialties

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• Critical Care Medicine
• Pulmonology
• Sleep Medicine

Accepted Insurances

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Education

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• University of Vermont - Fletcher Allen Health Care
• Grant Medical College

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