Professor of Neurological Surgery, Yale University
Neurosurgery
Dr. Dennis D. Spencer, MD
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Dennis Spencer practices Neurosurgery. He studied medicine at Washington University School of Medicine in St. Louis. He over the years received 8 awards: "Top Doctors: New York Metro Area", "America's Top Doctors", "CMS Meaningful Use Stage 1 Certification", "New York Magazine: Top Doctors", "Fellow (FACS)", "Fellow (FAANS)", "Top MD" and "Whos Who in Medicine and Healthcare". Dr. Dennis D. Spencer is a published doctor. He has 84 publications published. The most current publication "50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate." Dennis Spencer accepts Medicare payments and is registered with Medicare.gov.
Publications
- A comparison of the power spectral density of scalp EEG and subjacent electrocorticograms.
- 50 Hz hippocampal stimulation in refractory Epilepsy: Higher level of basal glutamate predicts greater release of glutamate.
- Spatial memory for asymmetrical dot locations predicts lateralization among patients with presurgical mesial temporal lobe Epilepsy.
- The spatial and signal characteristics of physiologic high frequency oscillations.
- Seizure control for intracranial arteriovenous malformations is directly related to treatment modality: a meta-analysis.
- Ictal spread of medial temporal lobe seizures with and without secondary generalization: An intracranial electroencephalography analysis.
- Reply to about the electrophysiological basis of resting state networks.
- Intracranial EEG evaluation of relationship within a resting state network.
- Seizure localization using three-dimensional surface projections of intracranial EEG power.
- Intracranially recorded interictal spikes: Relation to seizure onset area and effect of medication and time of day.
- 7T MR spectroscopic imaging in the localization of surgical Epilepsy.
- Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe Epilepsy.
- Loss of Perivascular Kir4.1 Potassium Channels in the Sclerotic Hippocampus of Patients With Mesial Temporal Lobe Epilepsy.
- Redistribution of monocarboxylate transporter 2 on the surface of astrocytes in the human epileptogenic hippocampus.
- Selective homonuclear polarization transfer for spectroscopic imaging of GABA at 7T.
- Functional MRI connectivity as a predictor of the surgical outcome of Epilepsy.
- Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus.
- The Corollary Discharge in Humans Is Related to Synchronous Neural Oscillations.
- Astrocytes and Epilepsy.
- Intraoperative anatomic landmarks for resection of the amygdala during medial temporal lobe surgery.
- Visual memory in patients after anterior right temporal lobectomy and adult normative data for the Brown Location Test.
- Image-guided intraoperative cortical deformation recovery using game theory: application to neocortical Epilepsy surgery.
- Harvey Cushing as a book collector, bibliophile, and archivist: the precedence for the genesis of the Brain Tumor Registry. Historical vignette.
- Language lateralization in Epilepsy patients: fMRI validated with the Wada procedure.
- Doublecortin expression in adult cat and primate Cerebral cortex relates to immature neurons that develop into GABAergic subgroups.
- Curing Epilepsy: progress and future directions.
- Novel interaction techniques for neurosurgical planning and stereotactic navigation.
- Local spatial effect of 50 Hz cortical stimulation in humans.
- Effects of working memory load on oscillatory power in human intracranial EEG.
- Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in Epilepsy patients.
- Multiphoton fluorescence lifetime imaging of intrinsic fluorescence in human and rat Brain tissue reveals spatially distinct NADH binding.
- Remote cerebellar Hemorrhage and iliofemoral vein thrombosis after supratentorial craniotomy.
- Neurometabolism in human Epilepsy.
- Gene expression in temporal lobe Epilepsy is consistent with increased release of glutamate by astrocytes.
- Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe Epilepsy.
- The evolution of Harvey Cushing's surgical approach to pituitary Tumors from transsphenoidal to transfrontal.
- Normal magnetic resonance imaging and medial temporal lobe Epilepsy: the clinical syndrome of paradoxical temporal lobe Epilepsy.
- Cushing's experience with the surgical treatment of Spinal dysraphism.
- Early evolution of neurological surgery: conquering increased intracranial pressure, infection, and blood loss.
- Battling blood loss in neurosurgery: Harvey Cushing's embrace of electrosurgery.
- Extracellular metabolites in the cortex and hippocampus of epileptic patients.
- Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus.
- The development of techniques for resection of spinal cord Tumors by Harvey W. Cushing.
- Effect of an external responsive neurostimulator on seizures and electrographic discharges during subdural electrode monitoring.
- Intracarotid Amytal memory test and hippocampal magnetic resonance imaging volumetry: validity of the Wada test as an indicator of hippocampal integrity among candidat...
- Mesial temporal lobe Epilepsy: a proton magnetic resonance spectroscopy study and a histopathological analysis.
- Harvey W. Cushing and cerebrovascular surgery: Part I, Aneurysms.
- Harvey W. Cushing and cerebrovascular surgery: Part II, Vascular malformations.
- Long-term outcome after Epilepsy surgery for focal cortical dysplasia.
- Partial Epilepsy presenting as episodic dyspnea: a specific network involved in limbic seizure propagation. Case report.
- Linking hemodynamic and electrophysiological measures of Brain activity: evidence from functional MRI and intracranial field potentials.
- Inauguration of pediatric neurosurgery by Harvey W. Cushing: his contributions to the surgery of posterior fossa Tumors in children. Historical vignette.
- Increased expression of erythropoietin receptor on blood vessels in the human epileptogenic hippocampus with sclerosis.
- 1H and 31P spectroscopic imaging of Epilepsy: spectroscopic and histologic correlations.
- Use of an anteromedial subdural strip electrode in the evaluation of medial temporal lobe Epilepsy. Technical note.
- Physiology of human cortical neurons adjacent to cavernous malformations and Tumors.
- Temporal lobe tumoral Epilepsy: characteristics and predictors of surgical outcome.
- N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
- A retrospective analysis of hippocampal pathology in human temporal lobe Epilepsy: evidence for distinctive patient subcategories.
- Surgical management of parietal lobe Epilepsy.
- Neuronal and glial metabolite content of the epileptogenic human hippocampus.
- 1H and 31P spectroscopy and bioenergetics in the lateralization of seizures in temporal lobe Epilepsy.
- Glutamate-glutamine cycling in the epileptic human hippocampus.
- Frontal lobe tumoral Epilepsy: clinical, neurophysiologic features and predictors of surgical outcome.
- Striking differences in glucose and lactate levels between Brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia.
- Surgery for focal cortical dysplasia.
- What is a seizure focus?
- Novel expression of AMPA-receptor subunit GluR1 on mossy cells and CA3 pyramidal neurons in the human epileptogenic hippocampus.
- Gabapentin and vigabatrin increase GABA in the human neocortical slice.
- Emerging surgical and radiotherapeutic techniques for treating Epilepsy.
- Intraoperative optical imaging of human face cortical topography: a case study.
- Non-enhancing de novo glioblastoma: report of two cases.
- Correlations between granule cell physiology and bioenergetics in human temporal lobe Epilepsy.
- GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus.
- Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe Epilepsy.
- Increased expression of phosphate-activated glutaminase in hippocampal neurons in human mesial temporal lobe Epilepsy.
- From medical image computing to computer-aided intervention: development of a research interface for image-guided navigation.
- A comprehensive system for intraoperative 3D Brain deformation recovery.
- Localization-related Epilepsy exhibits significant connectivity away from the seizure-onset area.
- A decrease in EEG energy accompanies anti-epileptic drug taper during intracranial monitoring.
- Background intracranial EEG spectral changes with anti-epileptic drug taper.
- Social network theory applied to resting-state fMRI connectivity data in the identification of Epilepsy networks with iterative feature selection.
- Impaired consciousness in temporal lobe seizures: role of cortical slow activity.
Schools
Washington University St Louis
Barnes Jewish Hospital
Yale New Haven Hospital
Procedures Preformed
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Deep Brain Stimulation
- Lamina Procedures (incl. Laminectomy, Laminoplasty, Laminotomy)
- Pituitary Gland Tumor Excision
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Conditions Treated
- Acoustic Neuroma
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Aneurysm
- Brain Cancer
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- Top Doctors: New York Metro Area
- America's Top Doctors
- CMS Meaningful Use Stage 1 Certification
- New York Magazine: Top Doctors
- Fellow (FACS)
- Fellow (FAANS)
- Top MD
- Whos Who in Medicine and Healthcare
Education
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Yale-New Haven Hospital -
Washington University - Barnes-Jewish Hospital -
Washington University School of Medicine in St. Louis
Hospital
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Yale-New Haven Hospital
Drug Facts
| NPI NUMBER | 1316928211 | |
| NPPES Provider LastName | SPENCER | |
| NPPES Provider FirstName | DENNIS | |
| NPPES Provider ZIPCode | 065191369 | |
| NPPES Provider State | CT | |
| Specialty Description | Neurology | |
| Total Claim Count | 12.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1316928211 |
| Last Name Of The Provider | SPENCER |
| First Name Of The Provider | DENNIS |
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