Visiting Professor, Pathology, Albert Einstein College of Medicine
Pathology
Dr. Dennis W. Dickson, MD
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Doctor Dennis W. Dickson, MD practices Pathology. He went to University of Iowa Carver College of Medicine. University of Iowa Carver College of Medicine is ranked 29 in research and 16 in primary care medicine Dennis Dickson is a published physician. He published 101 publications, including: 'Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP-C.'
Publications
- C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells.
- Adult-onset cerebello-brainstem dominant form of X-linked adrenoleukodystrophy presenting as multiple system atrophy: case report and literature review.
- Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.
- Suspected non-Alzheimer disease pathophysiology - concept and controversy.
- Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP-C.
- Mixed tau and TDP-43 pathology in a patient with unclassifiable primary progressive aphasia.
- Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model.
- Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease.
- Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.
- TDP-43 and pathological subtype of Alzheimer's disease impact clinical features.
- Globular Glial Tauopathy Presenting as Semantic Variant Primary Progressive Aphasia.
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
- Evaluating pathogenic dementia variants in posterior cortical atrophy.
- Chronic traumatic encephalopathy pathology in a neurodegenerative disorders brain bank.
- Molecular Characterization of Meloidogyne christiei Golden and Kaplan, 1986 (Nematoda, Meloidogynidae) Topotype Population Infecting Turkey Oak (Quercus laevies) in Fl...
- Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS.
- Defining neurodegeneration on Guam by targeted genomic sequencing.
- Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum.
- Clinical presentation of a patient with SLC20A2 and THAP1 deletions: Differential diagnosis of oromandibular dystonia.
- Cognitive profile of LRRK2-related Parkinson's disease.
- Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies.
- Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States.
- Primary age-related tauopathy (PART): a common pathology associated with human aging.
- Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease.
- Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A.
- Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease: A Genome-Wide Association Study.
- PRKAR1B mutations are a rare cause of FUS negative neuronal intermediate filament inclusion disease.
- Three sib-pairs of autopsy-confirmed progressive supranuclear palsy.
- Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia.
- Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.
- Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias.
- Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS.
- A familial form of parkinsonism, dementia, and motor neuron disease: A longitudinal study.
- Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease.
- Validation of a Serum Screen for Alzheimer's Disease Across Assay Platforms, Species, and Tissues.
- Frontotemporal dementia and its subtypes: a genome-wide association study.
- Differential clinicopathologic and genetic features of late-onset amnestic dementias.
- Concurrent variably protease-sensitive prionopathy and amyotrophic lateral sclerosis.
- FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage.
- Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers.
- Genetic Screening and Functional Characterization of PDGFRB Mutations Associated With Basal Ganglia Calcification of Unknown Etiology.
- TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism.
- Expanded C9ORF72 Hexanucleotide Repeat in Depressive Pseudodementia.
- Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson's Disease.
- Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease.
- TDP-43 is a key player in the clinical features associated with Alzheimer's disease.
- Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.
- FDG-PET in pathologically confirmed spontaneous 4R-tauopathy variants.
- Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients.
- Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease.
- Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias.
- Regional proton magnetic resonance spectroscopy patterns in dementia with Lewy bodies.
- TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.
- Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study.
- Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia.
- Staging TDP-43 pathology in Alzheimer's disease.
- Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration.
- SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia.
- Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood.
- Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study.
- LRRK2 phosphorylates novel tau epitopes and promotes tauopathy.
- Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations.
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
- Midbrain atrophy is not a biomarker of progressive supranuclear palsy pathology.
- Neurocognitive speed associates with frontotemporal lobar degeneration TDP-43 subtypes.
- Endogenous Tau Aggregates in Oligodendrocytes of rTg4510 Mice Induced by Human P301L Tau.
- TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.
- Population-specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO-PD) consortium.
- Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.
- Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72.
- The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons.
- Clinicopathologic variability of the GRN A9D mutation, including amyotrophic lateral sclerosis.
- Similarities between familial and sporadic autopsy-proven progressive supranuclear palsy.
- Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia.
- Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
- Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites.
- Pallidonigroluysian atrophy associated with p.A152T variant in MAPT.
- Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS.
- Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia.
- Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder.
- Clinical and electrophysiologic variability in amyotrophic lateral sclerosis within a kindred harboring the C9ORF72 repeat expansion.
- CSF1R mutations link POLD and HDLS as a single disease entity.
- Quantitative neurofibrillary tangle density and brain volumetric MRI analyses in Alzheimer's disease presenting as logopenic progressive aphasia.
- Relationship of neighboring tissue and gliosis to ?-synuclein pathology in a fetal transplant for Parkinson's disease.
- C9ORF72 repeat expansions and other FTD gene mutations in a clinical AD patient series from Mayo Clinic.
- American Journal of Neurodegenerative Disease: Editorial Board (2012) e-Century Publishing Corporation.
- Launch of american journal of neurodegenerative disease.
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS.
- Pathology and temporal onset of visual hallucinations, misperceptions and family misidentification distinguishes dementia with Lewy bodies from Alzheimer's disease.
- Corticospinal tract degeneration associated with TDP-43 type C pathology and semantic dementia.
- Frontal asymmetry in behavioral variant frontotemporal dementia: clinicoimaging and pathogenetic correlates.
- Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion.
- Polysomnographic findings in dementia with Lewy bodies.
- Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amylo...
- Corticobasal degeneration with olivopontocerebellar atrophy and TDP-43 pathology: an unusual clinicopathologic variant of CBD.
- Criteria for the diagnosis of corticobasal degeneration.
- TARDBP mutations in Parkinson's disease.
- Ultrastructure of ubiquitin-positive, TDP-43-negative neuronal inclusions in cerebral cortex of C9ORF72-linked frontotemporal lobar degeneration/amyotrophic lateral sc...
- Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
- Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype.
Schools
Roy J Lucille a Carver College Of Medicine At University Of Iowa
Bronx MuniEinstein Med College
Albert Einstein College Med
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
Education
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Albert Einstein College of Medicine at Jacobi Medical Center -
University of Iowa Carver College of Medicine
Hospital
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Mayo Clinic - Jacksonville, Florida
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