Associate Professor, Medicine, University of Washington School of Medicine

Oncology

Doctor Derek L. Stirewalt, MD practices Oncology. Derek L. Stirewalt is also published. He has 50 publications published. The lastest publication: "The Human Salivary Proteome is Radiation Responsive.' Derek Stirewalt is registered with Medicare and accepts Medicare payments.

Publications

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• The Human Salivary Proteome is Radiation Responsive.
• Proteomic Classification of Acute Leukemias by Alignment-Based Quantitation of LC-MS/MS Data Sets.
• Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with Acute myeloid leukemia: a SWOG report.
• Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric/adult AML: a report from the Children's Oncology Group and SWOG.
• Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory Acute myeloid leukaemia.
• Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma.
• Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA.
• Identification of radiation-induced expression changes in nonimmortalized human T Cells.
• Tumor necrosis factor polymorphism affects transplantation outcome in patients with myelodysplastic syndrome but not in those with chronic myelogenous Leukemia, indepe...
• Prevalence and prognostic implications of WT1 mutations in pediatric Acute myeloid leukemia (AML): a report from the Children's Oncology Group.
• Receptor tyrosine kinase alterations in AML - biology and therapy.
• The preferentially expressed antigen in melanoma (PRAME) inhibits Myeloid differentiation in normal hematopoietic and leukemic progenitor cells.
• Prevalence and prognostic implications of CEBPA mutations in pediatric Acute myeloid leukemia (AML): a report from the Children's Oncology Group.
• Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with Acute myeloid leukemia.
• Circulating microRNAs as stable blood-based markers for Cancer detection.
• Structural and numerical variation of FLT3/ITD in pediatric AML.
• Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic Leukemia modulates apoptosis and impairs NK function.
• Identification of genes with abnormal expression changes in Acute myeloid leukemia.
• Connective tissue growth factor (CTGF) expression and outcome in adult patients with Acute lymphoblastic leukemia.
• Hematopoietic Cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemia.
• Clinical implications of FLT3 mutations in pediatric AML.
• Gene expression profiling of adult Acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction.
• Size of FLT3 internal tandem duplication has prognostic significance in patients with Acute myeloid leukemia.
• Elevated expression of the AF1q gene, an MLL fusion partner, is an independent adverse prognostic factor in pediatric Acute myeloid leukemia.
• Fine-tuning PU.1.
• Single-stranded linear amplification protocol results in reproducible and reliable microarray data from nanogram amounts of starting RNA.
• Activating mutations of RTK/ras signal transduction pathway in pediatric Acute myeloid leukemia.
• Predictors of relapse and overall survival in Philadelphia chromosome-positive Acute lymphoblastic leukemia after transplantation.
• Malignancy: Tumor Suppressor Gene Aberrations in Acute Myelogenous Leukemia.
• The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia.
• Antibodies to N-terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylated.
• Gene expression changes in normal haematopoietic Cells.
• Tumour necrosis factor-induced gene expression in human marrow stroma: clues to the pathophysiology of MDS?
• Use of gene expression microarrays for the study of Acute leukemia.
• Novel FLT3 point mutations within exon 14 found in patients with Acute myeloid leukaemia.
• The role of FLT3 in haematopoietic malignancies.
• Molecular targets in Acute myelogenous leukemia.
• FLT3, RAS, and TP53 mutations in elderly patients with Acute myeloid leukemia.
• Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric Acute myeloid leukemia.
• p73 mutations and expression in adult de novo Acute myelogenous leukemia.
• Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific.
• Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or ove...
• Increased AF1q gene expression in high-risk Myelodysplastic syndrome.
• A distinctive nuclear morphology in Acute myeloid leukemia is strongly associated with loss of HLA-DR expression and FLT3 internal tandem duplication.
• A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare ''poor prognosis'' Myeloid maligna...
• Decreased IRF8 expression found in aging hematopoietic progenitor/stem Cells.
• Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.
• Gene expression patterns in myelodyplasia underline the role of apoptosis and differentiation in Disease initiation and progression.
• Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

Schools

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• University of North Carolina At Chapel Hill

• University Wash Seattle

Procedures Preformed

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• HPC Transplantation (Stem Cell Transplant)

Conditions Treated

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• Acute Leukemia
• Anal and Rectal Cancer
• Anemia
• Carcinoma in Situ
• View All

Doctors Specialties

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• Medical Oncology
• Oncology

Accepted Insurances

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Helpful Reviews

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Medicare Facts

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National Provider Identifier [NPI]	1093805947
Last Name Of The Provider	STIREWALT
First Name Of The Provider	DEREK
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