Professor of Ophthalmology, Johns Hopkins University School of Medicine; Guerrieri Professor of Genetic Engineering and Molecular Ophthalmology
Ophthalmology
Dr. Donald Zack, MD
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Donald Zack practices Ophthalmology. He studied medicine at Albert Einstein College of Medicine of Yeshiva University. Donald Zack is a published physician. He has 18 papers published. The most current publication "Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma."
Publications
- Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.
- Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.
- Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage.
- The Transcription Factor GTF2IRD1 Regulates the Topology and Function of Photoreceptors by Modulating Photoreceptor Gene Expression across the Retina.
- Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors.
- The Pex1-G844D mouse: A model for mild human Zellweger spectrum disorder.
- Hypomethylation of the IL17RC Promoter in Peripheral Blood Leukocytes Is Not A Hallmark of Age-Related Macular Degeneration.
- Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs.
- Alternative splicing and retinal degeneration.
- Construction of human activity-based phosphorylation networks.
- Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.
- Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line.
- Modeling retinal dystrophies using patient-derived induced pluripotent stem cells.
- A high content screening approach to identify molecules neuroprotective for photoreceptor cells.
- Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells.
- Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.
- RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.
Schools
Albert Einstein College of Medicine of Yeshiva University
Greenwich Hospital
Mass Ee Infirm
Wilmer Institute
Doctors Specialties
- Ophthalmology
Accepted Insurances
Education
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Massachusetts Eye & Ear Infirmary -
Albert Einstein College of Medicine of Yeshiva University
Hospital
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Howard County General Hospital -
Johns Hopkins Hospital
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