Physician
Anesthesiology
Dr. Edmond I. Eger, MD
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Doctor Edmond I. Eger, MD practices Anesthesiology. He went to Northwestern University Feinberg School of Medicine. Northwestern University Feinberg School of Medicine has a rank of 19 in research and a 29 in primary care Edmond Eger has written publications. He has 95 publications published with PubMed. The lastest publication is: 'Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABAA receptor.'
Publications
- Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABAA receptor.
- Three memorable years.
- From the Journal archives: A harbinger of modern anesthesia.
- Gamma-Aminobutyric Acid Type A Receptor {beta}3 Subunit Forebrain-Specific Knockout Mice Are Resistant to the Amnestic Effect of Isoflurane.
- Ross C. Terrell, PhD, an Anesthetic Pioneer.
- Slowing of the hippocampal θ rhythm correlates with anesthetic-induced amnesia.
- Conserved role of unc-79 in ethanol responses in lightweight mutant mice.
- Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder.
- After you, please: the second Annual John W. Severinghaus Lecture on Translational Science.
- Cost in several flavors.
- Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane.
- Increasing the duration of isoflurane anesthesia decreases the minimum alveolar anesthetic concentration in 7-day-old but not in 60-day-old rats.
- Isoflurane suppresses stress-enhanced fear learning in a rodent model of post-traumatic stress disorder.
- A comparison of the molecular bases for N-methyl-D-aspartate-receptor inhibition versus immobilizing activities of volatile aromatic anesthetics.
- Obesity modestly affects inhaled anesthetic kinetics in humans.
- Alzheimer's disease and anesthesia: out of body, out of mind...or not?
- The effects of volatile aromatic anesthetics on voltage-gated Na+ channels expressed in Xenopus oocytes.
- Increases in spinal cerebrospinal fluid potassium concentration do not increase isoflurane minimum alveolar concentration in rats.
- Intrathecal veratridine administration increases minimum alveolar concentration in rats.
- Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
- Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms.
- Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility.
- General anesthetics have additive actions on three ligand gated ion channels.
- Inhaled anesthetics do not combine to produce synergistic effects regarding minimum alveolar anesthetic concentration in rats.
- Concentrations of isoflurane exceeding those used clinically slightly increase the affinity of methane, but not toluene, for water.
- Temporal and spatial determinants of sacral dorsal horn neuronal windup in relation to isoflurane-induced immobility.
- The ever-useful infrared analyzer.
- Sevoflurane concentrations in blood, brain, and lung after sevoflurane-induced death.
- Anesthetic properties of the ketone bodies beta-hydroxybutyric acid and acetone.
- Alterations in spinal, but not cerebral, cerebrospinal fluid Na+ concentrations affect the isoflurane minimum alveolar concentration in rats.
- The plasticizer di(2-ethylhexyl) phthalate modulates gamma-aminobutyric acid type A and glycine receptor function.
- Anesthetic-like modulation of a gamma-aminobutyric acid type A, strychnine-sensitive glycine, and N-methyl-d-aspartate receptors by coreleased neurotransmitters.
- Mouse chromosome 7 harbors a quantitative trait locus for isoflurane minimum alveolar concentration.
- Anesthetic properties of carbon dioxide in the rat.
- Desflurane hepatitis associated with hapten and autoantigen-specific IgG4 antibodies.
- Ammonia has anesthetic properties.
- Lidocaine, MK-801, and MAC.
- Anesthetic properties of some fluorinated oxolanes and oxetanes.
- The excitatory and inhibitory effects of nitrous oxide on spinal neuronal responses to noxious stimulation.
- Hexafluorobenzene acts in the spinal cord, whereas o-difluorobenzene acts in both brain and spinal cord, to produce immobility.
- Blockade of acetylcholine receptors does not change the dose of etomidate required to produce immobility in rats.
- Determination of the EC50 amnesic concentration of etomidate and its diffusion profile in brain tissue: implications for in vitro studies.
- Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gam...
- Do dopamine receptors mediate part of MAC?
- Propofol's effects on nociceptive behavior and spinal c-fos expression after intraplantar formalin injection in mice with a mutation in the gamma-aminobutyric acid-typ...
- Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers.
- Chirality in anesthesia I: minimum alveolar concentration of secondary alcohol enantiomers.
- Naloxone does not increase the minimum alveolar anesthetic concentration of sevoflurane in mice.
- The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms.
- Do N-methyl-D-aspartate receptors mediate the capacity of inhaled anesthetics to suppress the temporal summation that contributes to minimum alveolar concentration?
- Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics.
- Contrasting roles of the N-methyl-D-aspartate receptor in the production of immobilization by conventional and aromatic anesthetics.
- The ventilatory stimulant doxapram inhibits TASK tandem pore (K2P) potassium channel function but does not affect minimum alveolar anesthetic concentration.
- The complexity of recovery from anesthesia.
- Tutorial: context-sensitive decrement times for inhaled anesthetics.
- Temperatures in soda lime during degradation of desflurane, isoflurane, and sevoflurane by desiccated soda lime.
- Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.
- The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene.
- R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M ...
- Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear.
- How likely is awareness during anesthesia?
- Administration of epinephrine does not increase learning of fear to tone in rats anesthetized with isoflurane or desflurane.
- Illustrations of inhaled anesthetic uptake, including intertissue diffusion to and from fat.
- Solubility of volatile anesthetics in bovine white matter, cortical gray matter, thalamus, hippocampus, and hypothalamic area.
- Thiopental produces immobility primarily by supraspinal actions in rats.
- Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples.
- Isoflurane depresses windup of C fiber-evoked limb withdrawal with variable effects on nociceptive lumbar spinal neurons in rats.
- Characteristics of anesthetic agents used for induction and maintenance of general anesthesia.
- Fires from the interaction of anesthetics with desiccated absorbent.
- Mice with a melanocortin 1 receptor mutation have a slightly greater minimum alveolar concentration than control mice.
- Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane.
- Inhibition of spinal protein kinase C-epsilon or -gamma isozymes does not affect halothane minimum alveolar anesthetic concentration in rats.
- Insulin decreases isoflurane minimum alveolar anesthetic concentration in rats independently of an effect on the spinal cord.
- Women appear to have the same minimum alveolar concentration as men: a retrospective study.
- The use of the potassium channel activator riluzole to test whether potassium channels mediate the capacity of isoflurane to produce immobility.
- Safety of low-flow sevoflurane anesthesia in patients with chronically impaired renal function is not proven.
- Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration.
- Blockade of 5-HT2A receptors may mediate or modulate part of the immobility produced by inhaled anesthetics.
- Temporal summation governs part of the minimum alveolar concentration of isoflurane anesthesia.
- Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics.
- Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration.
- Halothane and isoflurane have additive minimum alveolar concentration (MAC) effects in rats.
- Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone.
- Spinal N-methyl-d-aspartate receptors may contribute to the immobilizing action of isoflurane.
- Glycine receptors mediate part of the immobility produced by inhaled anesthetics.
- Acetylcholine receptors and thresholds for convulsions from flurothyl and 1,2-dichlorohexafluorocyclobutane.
- Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine rec...
- Cyclosporine can increase isoflurane MAC.
- Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics.
- Isoflurane causes anterograde but not retrograde amnesia for pavlovian fear conditioning.
- Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory.
- Propofol, metabisulfite, and bronchoconstriction.
- Good news, bad news.
- A brief history of the origin of minimum alveolar concentration (MAC).
Schools
Northwestern Center Feinberg School of Medicine
St LukeS Hospital
Ia Med Center
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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University of Iowa Hospitals and Clinics -
Rush University Medical Center -
Northwestern University Feinberg School of Medicine
Hospital
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UCSF Medical Center
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