Physician
Emergency Medicine
Dr. Edward M. Stephens, MD
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Edward Stephens is an expert in the field of Emergency Medicine. He went to Baylor College of Medicine. Doctor Edward M. Stephens, MD is also a published MD. He has 97 publication published. The most recent publication is: Oral immunization of macaques with attenuated vaccine virus induces protection against vaginally transmitted AIDS. Edward Stephens accepts Medicare payments and is listed with Medicare.gov.
Publications
- The Role of the Single Deaminase Domain APOBEC3A in Virus Restriction, Retrotransposition, DNA Damage and Cancer.
- Compartmentalization of Simian Immunodeficiency Virus Replication within Secondary Lymphoid Tissues of Rhesus Macaques Is Linked to Disease Stage and Inversely Related...
- Cellular HIV-1 inhibition by truncated old world primate APOBEC3A proteins lacking a complete deaminase domain.
- Analysis of the N-terminal positively charged residues of the simian immunodeficiency virus Vif reveals a critical amino acid required for the antagonism of rhesus APO...
- Lentivirus restriction by diverse primate APOBEC3A proteins.
- Vpu downmodulates two distinct targets, tetherin and gibbon ape leukemia virus envelope, through shared features in the Vpu cytoplasmic tail.
- Simian-Human immunodeficiency viruses expressing chimeric subtype B/C Vpu proteins demonstrate the importance of the amino terminal and transmembrane domains in the ra...
- Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells.
- Nonpolarized expression of a secreted murine leukemia virus glycoprotein in polarized epithelial cells.
- Fetal hyperinsulinemia increases farnesylation of p21 Ras in fetal tissues.
- Assembly of animal viruses at cellular membranes.
- Isolation, sequence and differential expression of the p58 gene family of Babesia bigemina.
- Surface expression of viral glycoproteins is polarized in epithelial cells infected with recombinant vaccinia viral vectors.
- Sequence conservation among merozoite apical complex proteins of Babesia bovis, Babesia bigemina and other apicomplexa.
- Novel targets for HIV therapy.
- Effects of deletion of the cytoplasmic domain upon surface expression and membrane stability of a viral envelope glycoprotein.
- Induction of complement-dependent and -independent neutralizing antibodies by recombinant-derived human cytomegalovirus gp55-116 (gB).
- Processing of the glycoprotein of feline immunodeficiency virus: effect of inhibitors of glycosylation.
- Epstein-Barr virus glycoprotein gp85 associates with the BKRF2 gene product and is incompletely processed as a recombinant protein.
- Recombinant vaccinia virus expression of Anaplasma marginale surface protein MSP-1a: effect of promoters, leader sequences and GPI anchor sequence on antibody response.
- A physical map of the viral genome for infectious pancreatic necrosis virus Sp: analysis of cell-free translation products derived from viral cDNA clones.
- Polarized expression of a chimeric protein in which the transmembrane and cytoplasmic domains of the influenza virus hemagglutinin have been replaced by those of the v...
- Env-specific CTL predominate in cats protected from feline immunodeficiency virus infection by vaccination.
- A simian human immunodeficiency virus with a nonfunctional Vpu (deltavpuSHIV(KU-1bMC33)) isolated from a macaque with neuroAIDS has selected for mutations in env and n...
- Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing anti...
- Basolateral expression of a chimeric protein in which the transmembrane and cytoplasmic domains of vesicular stomatitis virus G protein have been replaced by those of ...
- Analysis of the amino terminal presequence of the feline immunodeficiency virus glycoprotein: effect of deletions on the intracellular transport of gp95.
- Involvement of gag- and env-specific cytotoxic T lymphocytes in protective immunity to feline immunodeficiency virus.
- HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors.
- The transmembrane glycoprotein of human immunodeficiency virus type 1 induces syncytium formation in the absence of the receptor binding glycoprotein.
- Selected models of HIV-induced neurological disease.
- Primate models of AIDS vaccine development.
- Restrictive type of replication of ovine/caprine lentiviruses in ovine fibroblast cell cultures.
- A molecular clone of simian-human immunodeficiency virus (DeltavpuSHIV(KU-1bMC33)) with a truncated, non-membrane-bound vpu results in rapid CD4(+) T cell loss and neu...
- Pathogenesis of lymphocyte-tropic and macrophage-tropic SIVmac infection in the brain.
- Manifestations of SIV-induced ocular pathology in macaque monkeys.
- Nucleotide substitutions in the long terminal repeat are not required for development of neurovirulence by simian immunodeficiency virus strain mac.
- Simian-human immunodeficiency virus-associated nephropathy in macaques.
- Morphological correlates of neurological dysfunction in macaques infected with neurovirulent simian immunodeficiency virus.
- Chimeric SHIV that causes CD4+ T cell loss and AIDS in rhesus macaques.
- Chronology of genetic changes in the vpu, env, and Nef genes of chimeric simian-human immunodeficiency virus (strain HXB2) during acquisition of virulence for pig-tail...
- Significance of macrophage tropism of SIV in the macaque model of HIV disease.
- Initial characterization of viral sequences from a SHIV-inoculated pig-tailed macaque that developed AIDS.
- Neuropathogenesis of chimeric simian/human immunodeficiency virus infection in pig-tailed and rhesus macaques.
- Simian immunodeficiency virus SIVmac chimeric virus whose env gene was derived from SIV-encephalitic brain is macrophage-tropic but not neurovirulent.
- Early treatment with 9-(2-phosphonylmethoxyethyl)adenine reduces virus burdens for a prolonged period in SIV-infected rhesus macaques.
- The proteins of lymphocyte- and macrophage-tropic strains of simian immunodeficiency virus are processed differently in macrophages.
- Failure of SIVmac to be neutralized in macrophage cultures is unique to SIVmac and not observed with neutralization of SHIV or HIV-1.
- Neutralizing antibodies administered before, but not after, virulent SHIV prevent infection in macaques.
- A cell-free stock of simian-human immunodeficiency virus that causes AIDS in pig-tailed macaques has a limited number of amino acid substitutions in both SIVmac and HI...
- Animal model of mucosally transmitted human immunodeficiency virus type 1 disease: intravaginal and oral deposition of simian/human immunodeficiency virus in macaques ...
- Plasmas from lymphocyte- and macrophage-tropic SIVmac-infected macaques have antibodies with a broader spectrum of virus neutralization activity in macrophage versus l...
- Neutralization of SIVmac239/17E in lymphocyte cultures involves virus strain-specific linear and conformational epitopes encoded by different regions of the env gene i...
- Prolonged infection in rhesus macaques with simian immunodeficiency virus (SIVmac239) results in animal-specific and rarely tissue-specific selection of nef variants.
- Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques.
- Pathogenesis of SIVmac infection in Chinese and Indian rhesus macaques: effects of splenectomy on virus burden.
- Lymphocyte-tropic simian immunodeficiency virus causes persistent infection in the brains of rhesus monkeys.
- Comparison of Vpu sequences from diverse geographical isolates of HIV type 1 identifies the presence of highly variable domains, additional invariant amino acids, and ...
- SIV-associated nephropathy in rhesus macaques infected with lymphocyte-tropic SIVmac239.
- Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques.
- Characterization of a neutralization-escape variant of SHIVKU-1, a virus that causes acquired immune deficiency syndrome in pig-tailed macaques.
- Passively administered neutralizing serum that protected macaques against infection with parenterally inoculated pathogenic simian-human immunodeficiency virus failed ...
- Oral immunization of macaques with attenuated vaccine virus induces protection against vaginally transmitted AIDS.
- Rhesus macaques infected with macrophage-tropic simian immunodeficiency virus (SIVmacR71/17E) exhibit extensive focal segmental and global glomerulosclerosis.
- Simian-human immunodeficiency virus (SHIV) containing the nef/long terminal repeat region of the highly virulent SIVsmmPBj14 causes PBj-like activation of cultured res...
- Infected macaques that controlled replication of SIVmac or nonpathogenic SHIV developed sterilizing resistance against pathogenic SHIV(KU-1).
- Comparison of Vif sequences from diverse geographical isolates of HIV type 1 and SIV(cpz) identifies substitutions common to subtype C isolates and extensive variation...
- HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions.
- Differential virus restriction patterns of rhesus macaque and human APOBEC3A: implications for lentivirus evolution.
- Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in v...
- The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein.
- Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C ...
- Early dysregulation of cripto-1 and immunomodulatory genes in the cerebral cortex in a macaque model of neuroAIDS.
- APOBEC3G expression is restricted to epithelial cells of the proximal convoluted tubules and is not expressed in the glomeruli of macaques.
- Membrane raft association of the Vpu protein of human immunodeficiency virus type 1 correlates with enhanced virus release.
- BST-2 mediated restriction of simian-human immunodeficiency virus.
- Comparison of the replication and persistence of simian-human immunodeficiency viruses expressing Vif proteins with mutation of the SLQYLA or HCCH domains in macaques.
- The Vpu protein: new concepts in virus release and CD4 down-modulation.
- Identification of amino acids within the second alpha helical domain of the human immunodeficiency virus type 1 Vpu that are critical for preventing CD4 cell surface e...
- Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.
- Mutations in the highly conserved SLQYLA motif of Vif in a simian-human immunodeficiency virus result in a less pathogenic virus and are associated with G-to-A mutatio...
- Longitudinal study to assess the safety and efficacy of a live-attenuated SHIV vaccine in long term immunized rhesus macaques.
- APOBEC3G expression is restricted to neurons in the brains of pigtailed macaques.
- A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian-human immunodeficiency virus (SH...
- Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensiti...
- Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed m...
- Identification of a region within the cytoplasmic domain of the subtype B Vpu protein of human immunodeficiency virus type 1 (HIV-1) that is responsible for retention ...
- Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains.
- Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus.
- Vpu: a multifunctional protein that enhances the pathogenesis of human immunodeficiency virus type 1.
- Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIV(KU-1bMC33)) results in the synthesis of two envelope precursor proteins, i...
- The primary phase of infection by pathogenic simian-human immunodeficiency virus results in disruption of the blood-brain barrier.
- The presence of the casein kinase II phosphorylation sites of Vpu enhances the CD4(+) T cell loss caused by the simian-human immunodeficiency virus SHIV(KU-lbMC33) in ...
- Infection of human astrocytoma cells with simian-human immunodeficiency virus results in up-regulation of gene expression and altered growth properties.
- Pathogenic and nef-interrupted simian-human immunodeficiency viruses traffic to the macaque CNS and cause astrocytosis early after inoculation.
- Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tail...
Schools
Baylor University
Doctors Specialties
- Emergency Medicine
Accepted Insurances
Education
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Baylor College of Medicine
Drug Facts
| NPI NUMBER | 1548230840 | |
| NPPES Provider LastName | STEPHENS | |
| NPPES Provider FirstName | EDWARD | |
| NPPES Provider ZIPCode | 783823333 | |
| NPPES Provider State | TX | |
| Specialty Description | Emergency Medicine | |
| Total Claim Count | 41.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 13.0 | |
| Percent Opioid Claims | 31.71 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1548230840 |
| Last Name Of The Provider | STEPHENS |
| First Name Of The Provider | EDWARD |
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