Physician
Rheumatology
Dr. Edward P. Amento, MD
Dr. Edward P. Amento works in the field of Rheumatology. He received 2 awards: "Fellow" and "Fellow (FACR)". Doctor Edward P. Amento, MD is a published doctor and has 72 publications published. The lastest was: 'Immunologic abnormalities in scleroderma.'
Publications
- Plaque array method and proteomics-based identification of biomarkers from Alzheimer's disease serum.
- The relaxin gene knockout mouse: a model of progressive scleroderma.
- The relaxin gene-knockout mouse: a model of progressive fibrosis.
- Relaxin-1-deficient mice develop an age-related progression of renal fibrosis.
- Relaxin is a key mediator of prostate growth and male reproductive tract development.
- Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.
- Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis.
- Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation.
- Induction of peripheral tolerance with peptide-specific anergy in experimental autoimmune neuritis.
- Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like diseas...
- Regulation of experimental autoimmune neuritis by transforming growth factor-beta 1.
- Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis.
- Modulation of synovial cell products by a factor from a human cell line: T lymphocyte induction of a mononuclear cell factor.
- 1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production...
- Glucocorticoids and collagen diseases.
- Cellular interactions and control of collagenase secretion in the synovium.
- Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes followi...
- Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on...
- 1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation.
- Immune interferon inhibits collagen synthesis by rheumatoid synovial cells associated with decreased levels of the procollagen mRNAs.
- Leu-M2 (Mac-120) is a platelet antigen and is not constitutively expressed by macrophages.
- Differential effects of 1,25-dihydroxyvitamin D3 on human lymphocytes and monocyte/macrophages: inhibition of interleukin-2 and augmentation of interleukin-1 production.
- Vitamin D and the immune system.
- Induction of dermal and subcutaneous inflammation by recombinant cachectin/tumor necrosis factor (TNF alpha) in the mouse.
- Gamma-interferon inhibits collagen synthesis in vivo in the mouse.
- 1,25-Dihydroxyvitamin D3 maintains adherence of human monocytes and protects them from thermal injury.
- Stimulation of procollagenase synthesis in human rheumatoid synovial fibroblasts by mononuclear cell factor/interleukin 1.
- Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis.
- T lymphocyte infiltrates in inflammatory synovia are oligoclonal.
- Clonal dominance among T-lymphocyte infiltrates in arthritis.
- Connective tissue metabolism including cytokines.
- Interleukin 1 production by the human monocyte cell line U937 requires a lymphokine induction signal distinct from interleukin 2 or interferons.
- The systemic administration of gamma interferon inhibits collagen synthesis and acute inflammation in a murine skin wounding model.
- The adenosine 3':5'-cyclic monophosphate response to prostaglandin E2 is altered in U937 cells in association with maturational events induced by activated T lymphocyt...
- Interferons and collagen production.
- Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts.
- Mechanisms of matrix degradation in rheumatoid arthritis.
- A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring. Clinical and histologic findings.
- TGF-beta and wound healing.
- Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.
- Rapid publication. TGF-beta 1 induces bone closure of skull defects.
- Bone morphogenetic protein-2b stimulation of growth and osteogenic phenotypes in rat osteoblast-like cells: comparison with TGF-beta 1.
- TGF-beta 1 accelerates wound healing: reversal of steroid-impaired healing in rats and rabbits.
- Connective tissue metabolism including cytokines in scleroderma.
- Stromelysin expression regulates collagenase activation in human fibroblasts. Dissociable control of two metalloproteinases by interferon-gamma.
- Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cyt...
- Relaxin alone and in conjunction with interferon-gamma decreases collagen synthesis by cultured human scleroderma fibroblasts.
- Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells.
- Immunoglobulin A in secretions from the lower human respiratory tract.
- Melanoma growth-stimulatory activity/GRO decreases collagen expression by human fibroblasts. Regulation by C-X-C but not C-C cytokines.
- Is rheumatoid arthritis driven by oligoclonal T cells?
- Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis.
- TGF-beta 1 induces bone closure of skull defects: temporal dynamics of bone formation in defects exposed to rhTGF-beta 1.
- Interleukin-1 and transforming growth factor-alpha: synergistic stimulation of metalloproteinases, PGE2, and proliferation in human fibroblasts.
- Characterization of radioiodinated recombinant human TGF-beta 1 binding to bone matrix within rabbit skull defects.
- Radiation pneumonitis. Bronchoalveolar lavage assessment and modulation by a recombinant cytokine.
- One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healing.
- Constitutive activation of the collagenase promoter in recessive dystrophic epidermolysis bullosa fibroblasts: role of endogenously activated AP-1.
- Transcriptional inhibition of stromelysin by interferon-gamma in normal human fibroblasts is mediated by the AP-1 domain.
- Immunologic abnormalities in scleroderma.
- Safety and pharmacokinetics of recombinant human relaxin in systemic sclerosis.
- The role of relaxin in glycodelin secretion.
- Connective tissue metabolism in scleroderma, including cytokines.
- Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo.
- Relaxin binds to and elicits a response from cells of the human monocytic cell line, THP-1.
- Monocyte chemotactic protein-1 (MCP-1) mRNA is down-regulated in human dermal fibroblasts by dexamethasone: differential regulation by TGF-beta.
- Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice.
- Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.
- Transforming growth factor beta (TGF-beta) and dexamethasone have direct opposing effects on collagen metabolism in low passage human dermal fibroblasts in vitro.
- Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor.
- The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias.
Schools
Albany Medical College
Doctors Specialties
- Internal Medicine
- Rheumatology
Accepted Insurances
Awards
- Fellow
- Fellow (FACR)
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