Associate Professor of Medicine, Channing Laboratory
Pulmonology
Dr. Edwin K. Silverman, MD
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Edwin Silverman works in the field of Pulmonology. He went to medical school at Washington University School of Medicine in St. Louis. He received awards:"Elected Member". Edwin Silverman is a published MD as well. He has 101 publications published. The latest was: Association Between Interstitial Lung Abnormalities and All-Cause Mortality. He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Sex-specific features of emphysema among current and former smokers with COPD.
- β-Blockers are associated with a reduction in COPD exacerbations.
- A genome-wide association study of Chronic obstructive pulmonary disease in hispanics.
- Identification of Five Chronic Obstructive Pulmonary Disease Subgroups with Different Prognoses in the ECLIPSE Cohort Using Cluster Analysis.
- Comparison between an Alternative and the Classic Definition of Chronic Bronchitis in COPDGene.
- Reduced Bone Density and Vertebral Fractures in Smokers: Men and COPD Patients at Increased Risk.
- A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in Asthma.
- Admixture mapping identifies a quantitative trait locus associated with FEV1/FVC in the COPDGene Study.
- PRIMUS: Rapid Reconstruction of Pedigrees from Genome-wide Estimates of Identity by Descent.
- Association between Occupational Exposure and Lung Function, Respiratory Symptoms, and High-Resolution Computed Tomography Imaging in COPDGene.
- Pneumothorax Risk Factors in Smokers with and without Chronic Obstructive Pulmonary Disease.
- Childhood-onset Asthma in smokers: Association between CT measures of airway size, lung function and chronic airflow obstruction.
- Radiological correlates and clinical implications of the paradoxical Lung function response to β2 agonists: an observational study.
- Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene.
- Genome-Wide Association Identifies Regulatory Loci Associated with Distinct Local Histogram Emphysema Patterns.
- Common Genetic Variants Associated with Resting Oxygenation in Chronic Obstructive Pulmonary Disease.
- The clinical and genetic features of COPD-Asthma overlap syndrome.
- Cardiovascular Disease is Associated with COPD Severity and Reduced Functional Status and Quality of Life.
- Risk loci for Chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
- Quantitative Computed Tomographic Measures of Pectoralis Muscle Area and Disease Severity in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.
- Clarification of the Risk of Chronic Obstructive Pulmonary Disease in α1-Antitrypsin Deficiency PiMZ Heterozygotes.
- Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema.
- Genome-wide Study of Percent Emphysema on CT in the General Population: The MESA Lung/SHARe Study.
- Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting.
- On the simultaneous association analysis of large genomic regions: a massive multi-locus association test.
- The clinical impact of non-obstructive chronic Bronchitis in current and former smokers.
- Heritability of Chronic obstructive pulmonary disease and related phenotypes in smokers.
- Pulmonary Function Reduction in Diabetes Mellitus with and without Chronic Obstructive Pulmonary Disease.
- Systemic sRAGE is a Biomarker of Emphysema and Associated with AGER Genetic Variants in COPD Patients.
- Distinct Quantitative CT Emphysema Patterns are Associated with Physiology and Function in Smokers.
- Faslodex inhibits estradiol-induced extracellular matrix dynamics and Lung metastasis in a model of lymphangioleiomyomatosis.
- Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene.
- GOLD 2011 disease severity classification in COPDGene: a prospective cohort study.
- Effect of Emphysema on CT scan measures of airway dimensions in smokers.
- Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells.
- Racial Differences in CT Phenotypes in COPD.
- Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.
- Developing new drug treatments in the era of network medicine.
- Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
- 'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.
- Genome-wide Association Analysis of Blood Biomarkers in COPD.
- Network medicine approaches to the genetics of complex Diseases.
- Genome Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction.
- Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease.
- Identification of a Chronic obstructive pulmonary disease genetic determinant that regulates HHIP.
- Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach.
- COPD association and repeatability of blood biomarkers in the ECLIPSE cohort.
- The clinical features of the overlap between COPD and Asthma.
- Identification of FGF7 as a novel susceptibility locus for Chronic obstructive pulmonary disease.
- Pro: Genome-Wide Association Studies (GWAS) in Asthma.
- SOX5 Is a Candidate Gene for Chronic Obstructive Pulmonary Disease Susceptibility and Is Necessary for Lung Development.
- Association of SERPINE2 with Asthma.
- Combining Disease Models to Test for Gene-Environment Interaction in Nuclear Families.
- Clinical and radiographic correlates of hypoxemia and oxygen therapy in the COPDGene study.
- On the follow-up of genome-wide association studies: an overall test for the most promising SNPs.
- Polymorphisms in surfactant protein-D are associated with Chronic obstructive pulmonary disease.
- Intrathoracic tracheal volume and collapsibility on inspiratory and end-expiratory ct scans correlations with lung volume and Pulmonary function in 85 smokers.
- The relationship between small pulmonary vascular alteration and aortic atherosclerosis in Chronic obstructive pulmonary disease: quantitative CT analysis.
- 뱉-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts.
- Genome-Wide Association Analysis of Body Mass in Chronic Obstructive Pulmonary Disease.
- Airway count and Emphysema assessed by chest CT imaging predicts clinical outcome in smokers.
- Chronic obstructive pulmonary disease phenotypes: the future of COPD.
- Multistudy fine mapping of chromosome 2q identifies XRCC5 as a Chronic obstructive pulmonary disease susceptibility gene.
- Quantitative assessment of bronchial wall attenuation with thin-section CT: An indicator of airflow limitation in Chronic obstructive pulmonary disease.
- Collapsibility of Lung volume by paired inspiratory and expiratory CT scans: correlations with Lung function and mean Lung density.
- Variants in FAM13A are associated with Chronic obstructive pulmonary disease.
- Pulmonary function and emphysema in Williams-Beuren syndrome.
- Identification of early interstitial lung disease in smokers from the COPDGene Study.
- Quantitative CT measurement of cross-sectional area of small pulmonary vessel in COPD: correlations with emphysema and airflow limitation.
- Stronger evidence for replication of NPPA using genome-wide genotyping data.
- MMP12, lung function, and COPD in high-risk populations.
- Sex differences in emphysema and airway Disease in smokers.
- On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association st...
- Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.
- Genetics and genomics of Chronic obstructive pulmonary disease.
- Genetics of COPD and emphysema.
- Airway wall attenuation: a biomarker of airway disease in subjects with COPD.
- Clinical practice. Alpha1-antitrypsin deficiency.
- Assessing the reproducibility of Asthma candidate gene associations, using genome-wide data.
- Analysis of exonic elastin variants in severe, early-onset Chronic obstructive pulmonary disease.
- Genome-wide association analysis identifies PDE4D as an Asthma-susceptibility gene.
- Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.
- Molecular biomarkers for quantitative and discrete COPD phenotypes.
- A genome-wide association study of Pulmonary function measures in the Framingham Heart Study.
- Three-dimensional airway measurements and algorithms.
- High-resolution melting curve analysis of genomic and whole-genome amplified DNA.
- alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note.
- Polymorphic variation in surfactant protein B is associated with COPD exacerbations.
- Testing and estimating gene-environment interactions in family-based association studies.
- National Emphysema Treatment Trial state of the art: genetics of Emphysema.
- On the replication of genetic associations: timing can be everything!
- IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
- Exacerbations in Chronic obstructive pulmonary disease: do they contribute to disease progression?
- Computed tomography phenotypes in severe, early-onset Chronic obstructive pulmonary disease.
- A common mitochondrial haplogroup is associated with elevated total serum IgE levels.
- Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline.
- Polymorphisms in IL13, total IgE, eosinophilia, and Asthma exacerbations in childhood.
- Genetic determinants of Emphysema distribution in the national Emphysema treatment trial.
- A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-catenin.
- Association Between Interstitial Lung Abnormalities and All-Cause Mortality.
Schools
Washington University In St Louis School Of Medicine
Brigham and Women39s Hospital
Conditions Treated
- Asthma
- Bronchiectasis
- Bronchitis
- COPD (Chronic Obstructive Pulmonary Disease)
- View All
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Awards
- Elected Member
Education
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Brigham and Women's Hospital -
Washington University School of Medicine in St. Louis
Hospital
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Brigham and Women's Hospital
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