Professor, Pediatrics, Perelman School of Medicine
Pediatric Hematology & Oncology
Dr. Frank M. Balis, MD
Frank Balis works in the field of Pediatric Hematology & Oncology. He studied medicine at Vanderbilt University School of Medicine. Frank Balis is a published doctor and has 57 publications published. The lastest was: 'Comparative pharmacokinetics, safety, and tolerability of two sources of ch14.18 in pediatric patients with high-risk neuroblastoma following myeloablative therapy.'
Publications
- Comparative pharmacokinetics, safety, and tolerability of two sources of ch14.18 in pediatric patients with high-risk neuroblastoma following myeloablative therapy.
- Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children an...
- Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: A report from the Children's Oncology Group.
- Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.
- Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
- A Qualitative Study of Phase III Cancer Clinical Trial Enrollment Decision-Making: Perspectives from Adolescents, Young Adults, Caregivers, and Providers.
- Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neur...
- Time to disease progression in children with relapsed or refractory neuroblastoma treated with ABT-751: A report from the Children's Oncology Group (ANBL0621).
- Vandetanib in Children and Adolescents with Multiple Endocrine Neoplasia Type 2B Associated Medullary Thyroid Carcinoma.
- Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell Lymphoma: a Children's Oncology Group phase 1 consorti...
- Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas.
- A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis®, ET-743) in children and adolescents with relapsed or refractory solid tumors.
- A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain T...
- Automated volumetric growth plate measurement using magnetic resonance imaging for monitoring skeletal toxicity in children treated on investigational drug trials.
- The plasma and cerebrospinal fluid pharmacokinetics of the platinum analog satraplatin after intravenous administration in non-human primates.
- Pediatric phase I trial and pharmacokinetic study of dasatinib: a report from the children's oncology group phase I consortium.
- Phase 1 trial and pharmacokinetic study of the farnesyl transferase inhibitor tipifarnib in children and adolescents with refractory leukemias: a report from the Child...
- A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical Cancer.
- A phase 1 trial and pharmacokinetic study of cediranib, an orally bioavailable pan-vascular endothelial growth factor receptor inhibitor, in children and adolescents w...
- The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates.
- Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced Renal dysfunction: clinical and pharmacologic factors affecting outcome.
- Pediatric phase I trial design using maximum target inhibition as the primary endpoint.
- Phase II trial of ixabepilone administered daily for five days in children and young adults with refractory solid tumors: a report from the children's oncology group.
- Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polyme...
- Dexrazoxane as a cardioprotectant in children receiving anthracyclines.
- Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
- Conformational heterogeneity and quasi-static self-quenching in DNA containing a fluorescent guanine analogue, 3MI or 6MI.
- The legacy of Cancer therapy in children.
- Trabectedin.
- Sorafenib and sunitinib.
- Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors.
- Characteristics and outcome of pediatric patients enrolled in phase I oncology trials.
- A phase I study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 21 days every 28 days in pediatric patients with solid tumors.
- Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leuke...
- A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch,...
- A phase 1 study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 7 days every 21 days in pediatric patients with solid tumors.
- Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexif...
- Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infection.
- Phase I study of O6-benzylguanine and temozolomide administered daily for 5 days to pediatric patients with solid tumors.
- A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days.
- Intrathecal mafosfamide: a preclinical pharmacology and phase I trial.
- Plasma and cerebrospinal fluid pharmacokinetics of intravenous oxaliplatin, cisplatin, and carboplatin in nonhuman primates.
- A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast Cancer.
- Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.
- Loss of Smad3 in acute T-cell lymphoblastic leukemia.
- High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma.
- Plasma and cerebrospinal fluid pharmacokinetics of imatinib after administration to nonhuman primates.
- Single-dose and steady-state pharmacokinetics of tenofovir disoproxil fumarate in human immunodeficiency virus-infected children.
- Evaluation and treatment of fever in the non-neutropenic child with Cancer.
- Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.
- Increased 99mTc-sestamibi accumulation in normal Liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576.
- Phase I clinical trial of intrathecal topotecan in patients with neoplastic meningitis.
- Pharmacokinetics of intrathecal gemcitabine in nonhuman primates.
- Zidovudine concentration in brain extracellular fluid measured by microdialysis: steady-state and transient results in rhesus monkey.
- Evolution of antiCancer drug discovery and the role of cell-based screening.
- Clinical trial design for target-based therapy.
Schools
Vanderbilt University
Van Chldns Hospital
Chldns or Hospital Med Center
Conditions Treated
- Anemia
- ENT Cancer
- Liver Cancer
- Lung Cancer
- View All
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
-
National Institutes of Health Clinical Center -
Vanderbilt University -
Vanderbilt University School of Medicine
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