Professor of Obstetrics and Gynecology, University Pennsylvania

Obstetrics & Gynecology

George Coukos is an expert in the field of Obstetrics & Gynecology. He has 3 awards "CMS Meaningful Use Stage 1 Certification", "Fellow (FACOG)" and "Super Doctor". George Coukos is also published. He has 23 publications published. The lastest publication: "Targeting the tumor vasculature to enhance T cell activity.'

Publications

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• Potential approaches for more successful dendritic cell-based immunotherapy.
• Targeting the tumor vasculature to enhance T cell activity.
• T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression.
• Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy.
• Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in Cancer.
• Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors.
• T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy.
• Development of 124I Immuno-PET Targeting Tumor Vascular TEM1/Endosialin.
• Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model.
• Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors--response.
• Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer.
• CD137 accurately identifies and enriches for naturally-occurring tumor-reactive T cells in tumor.
• A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside.
• Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide.
• Deciphering and reversing tumor immune suppression.
• Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T Cell Rejection Function in Tumors.
• Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian Cancer.
• Primary Human Ovarian Epithelial Cancer Cells Broadly Express HER2 at Immunologically-Detectable Levels.
• Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian Cancer neovascularization.
• Conference Scene: Immune signatures in the tumor and beyond.
• Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?
• Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian Cancer.

Schools

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• Universita Di Modena E Reggio Emilia Facolta Di Medicina E Chirurgia

• University Of Pa Health System

Procedures Preformed

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• Colposcopy
• Gynecologic Cancer Screening
• Hysterectomy - Laparoscopic
• Hysterectomy - Open
• View All

Conditions Treated

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• Carcinoma in Situ
• Cervical Cancer
• Cervical Polyps
• Fallopian Tube Cancer
• View All

Doctors Specialties

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• Gynecologic Oncology
• Obstetrics
• Gynecology

Accepted Insurances

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• Aetna HMO
• Personal Choice PPO
• Regional Pref Network EPO
• Regional Pref Network HMO
• Regional Pref Network HMO+
• Regional Pref Network POS+
• Regional Pref Network PPO
• Blue Card PPO
• Cigna HMO
• Cigna PPO
• Great West Healthcare-Cigna PPO
• Open Access Plus
• CoreSource
• Coventry Health America PPO
• First Health (Coventry Health Care) PPO
• Geisinger Health Plan
• HealthPartners
• Community Blue PPO
• Direct Access
• Horizon Blue Cross Blue Shield HMO
• Horizon Blue Cross Blue Shield POS
• Horizon Blue Cross Blue Shield PPO
• Choice Care PPO
• Keystone Health Plan East HMO
• Medicare MCR
• MultiPlan PPO
• Freedom Plan
• QualCare HMO
• QualCare PPO
• Choice Plus POS
• Navigate HMO
• Navigate POS
• Options PPO
• Oxford Liberty
• United Healthcare

Awards

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• CMS Meaningful Use Stage 1 Certification
• Fellow (FACOG)
• Super Doctor

Hospital

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• Hospital of the University of Pennsylvania

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