Physician
Anesthesiology
Dr. George Michalopoulos, MD
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George Michalopoulos works in the field of Anesthesiology. He went to University of Massachusetts Medical School. University of Massachusetts Medical School is ranked 49 in research and 12 in primary care medicine George Michalopoulos is a published doctor as well. He has 101 publications published. The latest was: Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and ep... Dr. George Michalopoulos accepts Medicare payments and is listed with Medicare.gov.
Publications
- Regulation of Liver Growth by Glypican 3, CD81, Hedgehog, and Hhex.
- Histological organization in hepatocyte organoid cultures.
- Myopodin, a synaptopodin homologue, is frequently deleted in invasive prostate cancers.
- The processing and utilization of hepatocyte growth factor/scatter factor following partial hepatectomy in the rat.
- Hepatocellular carcinomas in native livers from patients treated with orthotopic liver transplantation: biologic and therapeutic implications.
- Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration.
- Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth.
- Comparative genomic hybridization of hepatocellular carcinoma: correlation with fluorescence in situ hybridization in paraffin-embedded tissue.
- Recent advances in human hepatocyte culture systems.
- Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) ...
- [Hepatocyte transplantation. Possibilities for use and examples of practical clinical application].
- Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells.
- Serum-free, long-term cultures of human hepatocytes: maintenance of cell morphology, transcription factors, and liver-specific functions.
- Expression and activation of pro-MMP-2 and pro-MMP-9 during rat liver regeneration.
- STAT 1alpha/1beta, STAT 3 and STAT 5: expression and association with c-MET and EGF-receptor in long-term cultures of human hepatocytes.
- Cationic colloidal silica membrane perturbation as a means of examining changes at the sinusoidal surface during liver regeneration.
- Hepatocyte growth factor (HGF) and receptor (c-met) in normal and malignant astrocytic cells.
- Growth factor signal transduction immediately after two-thirds partial hepatectomy in the rat.
- Adrenergic stimulation of hepatocyte growth factor expression.
- Matrix-mediated changes in the expression of HNF-4alpha isoforms and in DNA-binding activity of ARP-1 in primary cultures of rat hepatocytes.
- Expression of the human hepatocyte growth factor cDNA in primary cultures of rat hepatocytes.
- Epidermal growth factor- and hepatocyte growth factor-receptor activity in serum-free cultures of human hepatocytes.
- Bcl-2 protein expression in acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma.
- The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice.
- Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and ep...
- Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice: interactions between the periductal...
- Dose-dependent biphasic effects of phenobarbital on growth and differentiation of primary culture rat hepatocytes.
- Growth and differentiation of rat hepatocytes: changes in transcription factors HNF-3, HNF-4, STAT-3, and STAT-5.
- Differential expression and distribution of focal adhesion and cell adhesion molecules in rat hepatocyte differentiation.
- Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor.
- Three-dimensional culture of hepatocytes in a continuously flowing medium.
- Phenobarbital suppresses growth and accelerates restoration of differentiation markers of primary culture rat hepatocytes in the chemically defined hepatocyte growth m...
- Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats.
- Antagonistic effects of dexamethasone and retinoic acid on rat lung morphogenesis.
- Glucocorticoid-induced effects on pattern formation and epithelial cell differentiation in early embryonic rat lungs.
- Differential modulation of hepatocyte growth factor-stimulated motility by transforming growth factor beta1 on rat liver epithelial cells in vitro.
- Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat.
- Matrix induced re-differentiation of cultured rat hepatocytes and changes of CCAAT/enhancer binding proteins.
- Expression of HGF and cMet in the developing and adult brain.
- Extracellular matrix remodeling at the early stages of liver regeneration in the rat.
- Bile ductular damage induced by methylene dianiline inhibits oval cell activation.
- Hepatocyte growth factor and c-MET in benign and malignant peripheral nerve sheath tumors.
- Immunodetection of c-met-oncogene''s protein product in renal cell neoplasia.
- Modifications of the hepatocyte growth factor/c-met pathway by constitutive expression of transforming growth factor-alpha in rat liver epithelial cells.
- Liver regeneration.
- Synergistic enhancement of EGF, but not HGF, stimulated hepatocyte motility by TGF-beta 1 in vitro.
- Expression of HGF mRNA in human rejecting kidney as evidenced by in situ hybridization.
- Synergistic effects of hepatocyte growth factor on human cord blood CD34+ progenitor cells are the result of c-met receptor expression.
- Hepatocyte growth factor mRNA in human liver cirrhosis as evidenced by in situ hybridization.
- Effects of hepatocellular mitogens on cytokine-induced nitric oxide synthesis in human hepatocytes.
- Keratinocyte growth factor and embryonic rat lung morphogenesis.
- Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes.
- Presence of urokinase in serum-free primary rat hepatocyte cultures and its role in activating hepatocyte growth factor.
- Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defi...
- Short exposure to hepatocyte growth factor stimulates adult human pancreatic beta-cell proliferation.
- HGF in liver regeneration and tumor promotion.
- Pathology and molecular diagnostics: issues of structure and organization.
- Hepatocyte growth factor, blood clearance, organ uptake, and biliary excretion in normal and partially hepatectomized rats.
- Metabolism of HGF-SF and its role in liver regeneration.
- The effect of octreotide on hepatic regeneration in rats.
- Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA.
- Comparative analysis of mitogenic and morphogenic effects of HGF and EGF on rat and human hepatocytes maintained in collagen gels.
- Expression and characterization of biologically active human hepatocyte growth factor (HGF) by insect cells infected with HGF-recombinant baculovirus.
- Structural and functional characterization of the mouse hepatocyte growth factor gene promoter.
- Uptake and distribution of hepatocyte growth factor in normal and regenerating adult rat liver.
- Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor.
- Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-alpha in adult rat liver.
- Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth fa...
- The mouse hepatocyte growth factor-encoding gene: structural organization and evolutionary conservation.
- Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas.
- Comparative effects of hepatocyte growth factor and epidermal growth factor on motility, morphology, mitogenesis, and signal transduction of primary rat hepatocytes.
- Distinct morphological and mito-inhibitory effects induced by TGF-beta 1, HGF and EGF on mouse, rat and human hepatocytes.
- Different proliferative responses of periportal and pericentral rat hepatocytes to hepatocyte growth factor.
- The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis.
- Immediate early detection of urokinase receptor after partial hepatectomy and its implications for initiation of liver regeneration.
- Hepatocyte growth factor inhibits cell proliferation in vivo of rat hepatocellular carcinomas induced by diethylnitrosamine.
- HGF and liver regeneration.
- Response of phenobarbital- and ciprofibrate-exposed hepatocytes to growth factors in type I collagen gels.
- Mitogenic effect of basic fibroblast growth factor and estradiol on cultured human myometrial and leiomyoma cells.
- Hepatocyte growth factor stimulates DNA synthesis in alveolar epithelial type II cells in vitro.
- Control mechanisms of liver regeneration.
- Lack of genotoxic activity of di(2-ethylhexyl)phthalate (DEHP) in rat and human hepatocytes.
- Response of hepatocytes transplanted into syngeneic hosts and heterotransplanted into athymic nude mice to peroxisome proliferators.
- Hepatocyte uptake of alpha 1-proteinase inhibitor-trypsin complexes in vitro: evidence for a shared uptake mechanism for proteinase complexes of alpha 1-proteinase inh...
- Hepatocyte receptors for antithrombin III-proteinase complexes.
- The survival of parenchymal hepatocytes irradiated with low and high LET radiation.
- Control of hepatocyte replication by two serum factors.
- Postnatal methyl mercury exposure: effects on ontogeny of renal and hepatic ornithine decarboxylase responses to trophic stimuli.
- Inhibition of DNA synthesis by chemical carcinogens in cultures of initiated and normal proliferating rat hepatocytes.
- Norepinephrine and epidermal growth factor: dynamics of their interaction in the stimulation of hepatocyte DNA synthesis.
- Proline is required for the stimulation of DNA synthesis in hepatocyte cultures by EGF.
- Phenobarbital enhances the aldehyde dehydrogenase activity of rat hepatocytes in vitro and in vivo.
- Changes in the pattern of aldehyde dehydrogenase activity in primary and metastatic adenocarcinomas of the human colon.
- Assessment of unscheduled and replicative DNA synthesis in hepatocytes treated in vivo and in vitro with unleaded gasoline or 2,2,4-trimethylpentane.
- Metabolism of benzo[a]pyrene in primary cultures of human hepatocytes: dose-response over a four-log range.
- Enhancement of the clonability of adult parenchymal hepatocytes with the liver tumor promoter phenobarbital.
- Effects of EGF and calcium on adult parenchymal hepatocyte proliferation.
- Mechanisms of rodent liver carcinogenesis.
- Enhancement of aldehyde dehydrogenase activity in human and rat hepatocyte cultures by 3-methylcholanthrene.
- Characterization of high molecular weight transforming growth factor alpha produced by rat hepatocellular carcinoma cells.
Schools
University of Massachusetts Worcester Campus
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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Baystate Medical Center - Tufts University -
University of Massachusetts Medical School
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1508844887 |
| Last Name Of The Provider | MICHALOPOULOS |
| First Name Of The Provider | GEORGE |
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