Physician
Infectious Disease
Dr. Gerald Medoff, MD
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Gerald Medoff is an expert in the field of Infectious Disease. He attended Washington University School of Medicine in St. Louis. He over the years received 1 awards: "Top MD". Doctor Gerald Medoff, MD is a published doctor. He published 99 publications, including: 'New challenges to the therapy of systemic fungal infections.'
Publications
- A pilot study of the management of uncomplicated candidemia with a standardized protocol of amphotericin B.
- New challenges to the therapy of systemic fungal infections.
- Formulary control of antimicrobial usage. What price freedom?
- Results of a rubella screening program for hospital employees: a five-year review (1986-1990).
- Screening of physicians for tuberculosis.
- Evaluation of rooms with negative pressure ventilation used for respiratory isolation in seven midwestern hospitals.
- Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes.
- Application of differential spectra in the ultraviolet-visible region to study the formation of amphotericin B-sterol complexes.
- Comparison of the ribonucleic acid polymerases from both phases of Histoplasma capsulatum.
- Balanced growth and morphogenesis of Histoplasma capsulatum in a defined synthetic medium.
- Effect of lipoproteins and altered lipid metabolism on the primary immune response in vitro.
- Relative avidity of etruscomycin to cholesterol and ergosterol.
- Increase in colony-forming units of Candida albicans after treatment with polyene antibiotics.
- Influence of extracellular K+ or Mg2+ on the stages of the antifungal effects of amphotericin B and filipin.
- Strategies in the treatment of systemic fungal infections.
- Role of cysteine in regulating morphogenesis and mitochondrial activity in the dimorphic fungus Histoplasma capsulatum.
- Potentiation of anticancer agents by amphotericin B.
- Possible relationship of morphogenesis in pathogenic fungus, Histoplasma capsulatum, to heat shock response.
- Sulfhydryl induced respiratory "shunt" pathways and their role in morphogenesis in the fungus, Histoplasma capsulatum.
- Purification and characterization of a cysteine dioxygenase from the yeast phase of Histoplasma capsulatum.
- Cutaneous mycobacteriosis: analysis of 34 cases with a new classification of the disease.
- Effect of exogenous lipids and lipoproteins on the primary immune response in vitro.
- Amphotericin B potentiation of the cytotoxicity of anticancer agents against both normal hematopoietic and leukemia cells in mice.
- Potentiation of cytotoxicity of anticancer agents by several different polyene antibiotics.
- Potentiation by amphotericin B of the cytotoxicity of anticancer agents against MOPC-315 plasmacytoma and Lewis lung carcinoma.
- Growth inhibition of Cryptococcus neoformans by cloned cultured murine macrophages.
- Interaction of plasma proteins and lipoproteins with amphotericin B.
- Antifungal action of rifampin.
- Antifungal chemotherapy.
- Antifungal agents useful in therapy of systemic fungal infections.
- Treatment of systemic mycoses with ketoconazole: emphasis on toxicity and clinical response in 52 patients. National Institute of Allergy and Infectious Diseases colla...
- Antifungal action of amphotericin B in combination with other polyene or imidazole antibiotics.
- Temperature- and cyclic nucleotide-induced phase transitions of Histoplasma capsulatum.
- Regulation of dimorphism in Histoplasma capsulatum by cyclic adenosine 3',5'-monophosphate.
- Stimulatory, permeabilizing, and toxic effects of amphotericin B on L cells.
- Therapeutic program for Candida infection.
- Treatment of osteomyelitis.
- Influenza virus infections. Current insights and their clinical applications.
- DNA--structure and enzymatic synthesis.
- Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms.
- Amphotericin B potentiation of rifampicin as an antifungal agent against the yeast phase of Histoplasma capsulatum.
- Listeriosis in humans: an evaluation.
- Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. 3. Osteomyelitis associated with vascular insufficiency.
- Methylation in the phage carried by escherichia coli 15T- (DNA methylation in phage psi).
- Thymineless death in Escherichia coli 15T- and recombinants of 15T- and Escherichia coli K-12.
- Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects (second of three parts).
- Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects.
- Induction of a defective phage and DNA methylation in Escherichia coli 15T-.
- Effects of rifamycin derivatives, alone and in combination with amphotericin B, against Histoplasma capsulatum.
- Ribonucleic acid polymerases of the yeast phase of Histoplasma capsulatum.
- Synergistic effect of amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea against a transplantable AKR leukemia.
- Permeability control in animal cells by polyenes: a possibility.
- Brief communication: polyene potentiation of antitumor agents.
- Changes in murine resistance to Listeria monocytogenes infection induced by amphotericin B.
- Characterization of the binding of amphotericin B to Saccharomyces cerevisiae and relationship to the antifungal effects.
- Uptake of Escherichia coli DNA into HeLa cells enhanced by amphotericin B.
- Potentiation of the antifungal effects of antibiotics by amphotericin B.
- A new therapeutic approach to Candida infections. A preliminary report.
- Nucleic acid and protein synthesis during thymineless death in lysogenic and nonlysogenic thymine auxotrophs.
- Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism).
- RNA metabolism during morphogenesis in Histoplasma capsulatum.
- Antifungal properties of polymyxin B and its potentiation of tetracycline as an antifungal agent.
- Sensitivity of transformed and nontransformed cells to amphotericin B and several rifamycin derivatives.
- Potentiation of rifampicin, rifampicin analogs, and tetracycline against animal cells by amphotericin B and polymyxin B.
- Antibiotic synergism against Listeria monocytogenes.
- Pneumonia caused by a pneumococcus resistant to erythromycin and lincomycin. Case report.
- Effects of elevation of serum cholesterol and administration of amphotericin B complexed to lipoproteins on amphotericin B-induced toxicity in rabbits.
- In vitro and in vivo comparisons of amphotericin B and N-D-ornithyl amphotericin B methyl ester.
- Involvement of oxidative damage in erythrocyte lysis induced by amphotericin B.
- Cross-reacting human and rabbit antibodies to antigens of Histoplasma capsulatum, Candida albicans, and Saccharomyces cerevisiae.
- Correlation between pathogenicity and temperature sensitivity in different strains of Histoplasma capsulatum.
- Toxicity and induction of resistance to Listeria monocytogenes infection by amphotericin B in inbred strains of mice.
- Antibiotic cost savings from formulary restrictions and physician monitoring in a medical-school-affiliated hospital.
- Mycelial- to yeast-phase transitions of the dimorphic fungi Blastomyces dermatitidis and Paracoccidioides brasiliensis.
- Pneumococcal endocarditis: report of a series and review of the literature.
- Amphotericin B-induced oxidative damage and killing of Candida albicans.
- Sensitivity of Candida albicans to amphotericin B administered as single or fractionated doses.
- Effects of serum lipoproteins on damage to erythrocytes and Candida albicans cells by polyene antibiotics.
- Heat-shock proteins induced during the mycelial-to-yeast transitions of strains of Histoplasma capsulatum.
- Two mechanisms of synergism when amphotericin B is used in combination with actinomycin D or 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea against the human promyelocyt...
- Aspergillosis in the immunocompromised host.
- Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks.
- Controversial areas in antifungal chemotherapy: short-course and combination therapy with amphotericin B.
- Role of cell defense against oxidative damage in the resistance of Candida albicans to the killing effect of amphotericin B.
- Interference with effects of amphotericin B on Candida albicans cells by 2-chloroethyl-1-nitrosoureas.
- Amphotericin B-resistant yeast infection in severely immunocompromised patients.
- Effects of the detergent sucrose monolaurate on binding of amphotericin B to sterols and its toxicity for cells.
- Morphogenesis and pathogenicity of Histoplasma capsulatum.
- Comparison of the in vitro and in vivo activity of the bis-triazole derivative UK 49,858 with that of amphotericin B against Histoplasma capsulatum.
- Classification of Histoplasma capsulatum isolates by restriction fragment polymorphisms.
- Irreversible block of the mycelial-to-yeast phase transition of Histoplasma capsulatum.
- Heat shock 70 gene is differentially expressed in Histoplasma capsulatum strains with different levels of thermotolerance and pathogenicity.
- Comparison of fluconazole and amphotericin B in treating histoplasmosis in immunosuppressed mice.
- Antimicrobial misuse in patients with positive blood cultures.
- Electrophoretic analysis of Histoplasma capsulatum chromosomal DNA.
- Effects of ascorbic acid on the antifungal action of amphotericin B.
- Concentration dependent dual effect of the monolauryl ester of sucrose on the antifungal activity and absorption spectra of amphotericin B (Fungizone).
- Comparison of the separation of Candida albicans chromosome-sized DNA by pulsed-field gel electrophoresis techniques.
Schools
Washington Center School of Medicine
New Eng Med Center
Boston City Hospital
Massachusetts General Hospital
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Top MD
Education
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Boston University Medical Center -
Tufts Medical Center -
Washington University School of Medicine in St. Louis
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