Physician
Pathology
Dr. Hesham M. Amin, MD
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Hesham Amin works in the field of Pathology. He graduated from Cairo University School of Medicine. Doctor Hesham M. Amin, MD has written publications. He has 76 publications published with PubMed. The lastest paper is: 'Sensitivity and specificity of the APC resistance assay in detection of individuals with factor V(Leiden)' Hesham Amin accepts Medicare payments and is registered with Medicare.gov.
Publications
- The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK(+) T-cell Lymphoma.
- 3D tissue-engineered model of Ewing's sarcoma.
- Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab.
- Requirement for Ssbp2 in Hematopoietic Stem Cell Maintenance and Stress Response.
- Sox4/Tcf7l1 axis promotes progression of BCR- ABL+ Acute lymphoblastic leukemia.
- The ALK inhibitor ASP3026 eradicates NPM-ALK⺠T-cell anaplastic large-cell Lymphoma in vitro and in a systemic xenograft Lymphoma model.
- Leukemic Phase of ALK(+) Anaplastic Large-Cell Lymphoma, Small-Cell Variant: Clinicopathologic Pitfalls of a Rare Entity.
- Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell Lymphoma.
- Bruton tyrosine kinase is commonly overexpressed in mantle cell Lymphoma and its attenuation by Ibrutinib induces apoptosis.
- Loss of p53 and altered miR15-a/16-1î²MCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human Leukemia cells.
- Modeling Ewing sarcoma tumors in vitro with 3D scaffolds.
- NPM-ALK upregulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism.
- An unusual case of aggressive systemic mastocytosis with associated refractory plasma Cell myeloma.
- MicroRNA-96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase Expression.
- Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid Leukemia.
- Expression and effects of inhibition of IGF-IR tyrosine kinase in mantle cell Lymphoma.
- Response of histiocytoses to imatinib mesylate: fire to ashes.
- IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell Lymphoma.
- IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell Lymphoma cells.
- Constitutive activation of the Wnt canonical pathway in mantle cell Lymphoma.
- Bone marrow involvement by marginal zone B-cell Lymphomas of different types.
- Granulocytic sarcoma with massive scalp involvement.
- BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous Leukemia.
- Pathobiology of ALK+ anaplastic large-cell Lymphoma.
- Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic Cells.
- Unusual expression of CD94 on CD8+ TCR-alpha beta T Cells in infectious mononucleosis.
- Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and Acute lymphoblastic leukemia.
- The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis.
- Immunoglobulin VH somatic hypermutation in mantle cell Lymphoma: mutated genotype correlates with better clinical outcome.
- SALL4, a novel oncogene, is constitutively expressed in human Acute myeloid leukemia (AML) and induces AML in transgenic mice.
- Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell Lymphoma.
- Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell Lymphoma cells.
- Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer.
- Intrinsic apoptotic pathway in anaplastic large cell Lymphoma.
- Jak3 contributes to the activation of ALK and Stat3 in ALK(+) anaplastic large cell Lymphoma.
- c-FLIP confers resistance to FAS-mediated apoptosis in anaplastic large-cell Lymphoma.
- Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and Cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and Cell cycle arrest of colon car...
- Jak3 activation is significantly associated with ALK expression in anaplastic large cell Lymphoma.
- Postsplenectomy cytomegaloviral mononucleosis: marked lymphocytosis, TCRgamma gene rearrangements, and impaired IgM response.
- Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell Lymphoma.
- Methylation of SHP1 gene and loss of SHP1 protein expression are frequent in systemic anaplastic large cell Lymphoma.
- MCL-1 expression in B-cell non-Hodgkin's Lymphomas.
- Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic Lymphoma kinase-posi...
- Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in Myelodysplastic syndrome.
- Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell Lymphoma.
- Characterization of 4 mantle cell Lymphoma cell lines.
- Composite thymoma and chronic lymphocytic Leukemia/small lymphocytic lymphoma involving the anterior mediastinum.
- Dissolution of the lymphoid follicle is a feature of the HHV8+ variant of plasma cell Castleman's Disease.
- Cutaneous and systemic plasmacytosis in a patient of Asian descent living in the United States.
- A comparison of the quantitation of macrophage foam Cell populations and the extent of apolipoprotein E deposition in developing atherosclerotic lesions in young peopl...
- Sensitivity and specificity of the APC resistance assay in detection of individuals with factor V(Leiden)
- Pathologic quiz case. A 22-year-old man with an abdominal mass.
- Hairy cell Leukemia with large cells: long disease course with adequate response to therapy.
- Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell Lymphoma with NPM-ALK (p80) fusion protein.
- Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in Acute promyelocytic leukaemia with t(15;17).
- Characterization of apoptosis induced by protein kinase C inhibitors and its modulation by the caspase pathway in Acute promyelocytic leukaemia.
- Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple Myeloma: downregulation of NF-kappa B induces apoptosis.
- High ZAP-70 expression correlates with worse clinical outcome in mantle cell Lymphoma.
- Restoration of shp1 expression by 5-AZA-2''-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell Lymphoma.
- Hedgehog signaling pathway is activated in diffuse large B-cell Lymphoma and contributes to tumor cell survival and proliferation.
- Decreased expression level of SH2 domain-containing protein tyrosine phosphatase-1 (Shp1) is associated with progression of Chronic myeloid leukaemia.
- Suppressor of cytokine signaling 3 expression in anaplastic large cell Lymphoma.
- Having a higher blast percentage in circulation than bone marrow: clinical implications in myelodysplastic syndrome and Acute lymphoid and myeloid leukemias.
- Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4.
- Interleukin-21 effectively induces apoptosis in mantle cell Lymphoma through a STAT1-dependent mechanism.
- Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell Lymphoma.
- SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability.
- Inhibition of JAK3 induces apoptosis and decreases anaplastic Lymphoma kinase activity in anaplastic large cell Lymphoma.
- Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell Lymphoma.
- Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell Lymphoma.
- Protein expression profiling of cytokines and cytokine receptors on purified chronic lymphocytic Leukemia cells from patients with favourable prognostic indicators.
- RIZ1 is potential CML tumor suppressor that is down-regulated during Disease progression.
- Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant Chronic myeloid leukaemia cells.
- Treatment of aggressive systemic mastocytosis with daclizumab.
- JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic Lymphoma kinase ...
Schools
KASR EL AINI COLLEGE OF MEDICINE UNIVERSITY OF CAIRO
George Wash University Med Center
Loyola University Med Center
University Tx MD Anderson Canc Center
Conditions Treated
- Acute Leukemia
- Anemia
- Chronic Myeloid Leukemia (CML)
- Deep Vein Thrombosis (DVT)
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Doctors Specialties
- Hematology
- Hematopathology
- Pathology
Accepted Insurances
Education
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Loyola University -
George Washington University -
Cairo University School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1487706958 |
| Last Name Of The Provider | AMIN |
| First Name Of The Provider | HESHAM |
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