Professor, Anesthesiology, University of Utah School of Medicine
Anesthesiology
Dr. Hiroshi Kamaya, MD
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Doctor Hiroshi Kamaya, MD works in the field of Anesthesiology. He graduated from Keio Gujuku University School of Medicine. Dr. Hiroshi Kamaya is a published physician as well. He has 83 publications published. The latest was: Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate.
Publications
- Do anesthetics act by competitive binding to specific receptors? Phase transition of firefly luciferase.
- The effects of temperature and pressure on the thermodynamic activity of anesthetics.
- Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate.
- Does pressure antagonize anesthesia? Opposite effects on specific and nonspecific inhibitors of firefly luciferase.
- Metallic mercury leak from the esophageal bougy and postoperative chest pain.
- Local anesthetics destabilize lipid membranes by breaking hydration shell: infrared and calorimetry studies.
- Acidosis and [K+].
- Structure-selective anesthetic action of steroids: anesthetic potency and effects on lipid and protein.
- Temperature-dependent effects of high pressure on the bioluminescence of firefly luciferase.
- Malignant hyperthermia and calcium-induced heat production.
- Pressure-anesthetic antagonism on the phase separation of non-ionic surfactant micelles.
- Surface activities of tertiary amine local anesthetics at air/water interface in the presence and absence of phospholipid monolayers.
- pH average rebuttal.
- [Anesthesiology--biochemical and physiochemical aspects].
- Partition equilibrium of inhalation anesthetics and alcohols between water and membranes of phospholipids with varying acyl chain-lengths.
- Adsorption of inhalation anesthetics on the air/water interface and the effect of water structure.
- Interfacial adsorption of an inhalation anesthetic onto ionic surfactant micelles and its desorption by high pressure.
- Anesthetics and high-pressure interaction upon elastic properties of a polymer membrane.
- Anesthetic-protein interaction. Random versus helix polylysine monolayers and interaction with 1-alkanols.
- Dissociation constants of local anesthetics and their temperature dependence.
- Benzyl alcohol penetration into micelles, dielectric constant of the binding site, partition coefficient and high-pressure squeeze-out.
- Molecular mechanisms of anesthesia.
- [Application of the theory of absolute reaction rate to the mechanism of general anesthesia--hydrophobic inhibition of firefly luminescence by anesthetics].
- Kinetic and thermodynamic aspects of the mechanism of general anesthesia in a model system of firefly luminescence in vitro.
- New endotracheal tube (Univent tube) for selective blockade of one lung.
- Alcohol effects on rapid kinetics of water transport through lipid membranes and location of the main barrier.
- Stopped-flow study of anesthetic effect on water-transport kinetics through phospholipid membranes. Interfacial versus lipid core ligands.
- Anesthetic-protein interaction: surface potential of bovine serum albumin estimated by a pH-sensitive dye.
- Do anesthetics fluidize membranes?
- Stopped-flow rapid kinetics of anesthetic-induced phase transition in phospholipid vesicle membranes: nonlocalized fluctuation.
- Molecular origin of biphasic response of main phase-transition temperature of phospholipid membranes to long-chain alcohols.
- Atypical Langmuir adsorption of inhalation anesthetics on phospholipid monolayer at various compressional states: difference between alkane-type and ether-type anesthe...
- Dose-dependent nonlinear response of the main phase-transition temperature of phospholipid membranes to alcohols.
- Anesthetics release unfreezable and bound water in partially hydrated phospholipid lamellar systems and elevate phase transition temperature.
- Miscibility of phosphatidylcholine binary mixtures in unilamellar vesicles: phase equilibria.
- Origin of calcium-induced minimum in bulk compressional modulus of lipid membranes. Configurational entropy of adsorbed Ca2+.
- Ketamine addiction.
- Fourier transform infrared studies on phospholipid hydration: phosphate-oriented hydrogen bonding and its attenuation by volatile anesthetics.
- [Future of inhalation anesthetics: structure-activity relationship].
- [Local anesthetics and the cell membrane].
- High pressure and anesthesia: pressure stimulates or inhibits bacterial bioluminescence depending upon temperature.
- Effect of surface ionization of dimyristoylphosphatidic acid vesicle membranes on the main phase-transition enthalpy and temperature.
- Activated carbon as a biological model: comparison between activated carbon adsorption and oil-water partition coefficient for drug activity correlation.
- Minimum drug dose to obtain adequate amnesia for cardioversion.
- [Heart transplantation and anesthesia].
- Depression of phase-transition temperature by anesthetics: nonzero solid membrane binding.
- Saturable and unsaturable binding of a volatile anesthetic enflurane with model lipid vesicle membranes.
- Smooth muscle contraction and local anesthetics: calmodulin-dependent myosin light-chain kinase.
- Changes in surface capacitance and conductance parallel to phospholipid membranes associated with phase transition: effects of halothane.
- Differential affinity of charged local anesthetics to solid-gel and liquid-crystalline states of dimyristoylphosphatidic acid vesicle membranes.
- Adsorption of local anesthetics on activated carbon: Freundlich adsorption isotherms.
- High pressure and anesthesia: compressibility, molal volume, and partial molal volume of volatile anesthetics.
- A solid-solution theory of anesthetic interaction with lipid membranes: temperature span of the main phase transition.
- Proton flow along lipid bilayer surfaces: effect of halothane on the lateral surface conductance and membrane hydration.
- Anesthesia cutoff phenomenon: interfacial hydrogen bonding.
- Interfacial dehydration by alcohols: hydrogen bonding of alcohols to phospholipids.
- Two-state model for nerve excitation and local anesthetic action.
- A statistical mechanical analysis of the effect of long-chain alcohols and high pressure upon the phase transition temperature of lipid bilayer membranes.
- High pressure antagonism of alcohol effects on the main phase-transition temperature of phospholipid membranes: biphasic response.
- Anesthetic-protein interaction: effects of volatile anesthetics on the secondary structure of poly(L-lysine).
- Interfacial dehydration by anesthetics: an electrocapillary study of surface charge density of adsorbed monolayer.
- Lateral conductance parallel to membrane surfaces: effects of anesthetics and electrolytes at pre-transition.
- Biphasic effects of alcohols on the phase transition of poly(L-lysine) between alpha-helix and beta-sheet conformations.
- Alcohol interaction with high entropy states of macromolecules: critical temperature hypothesis for anesthesia cutoff.
- pH of stomach contents.
- The alpha-helix to beta-sheet transition in poly(L-lysine): effects of anesthetics and high pressure.
- Alcohols dehydrate lipid membranes: an infrared study on hydrogen bonding.
- Combined effects of dissociable and undissociable local anesthetics upon ATP-induced firefly bioluminescence.
- Antagonism between high pressure and anesthetics in the thermal phase-transition of dipalmitoyl phosphatidylcholine bilayer.
- Reversible and irreversible inhibition by anesthetics of the calcium-induced luminescence of aequorin.
- Hydrophilic region of lecithin membranes studied by bromothymol blue and effects of an inhalation anesthetic, enflurane.
- Molecular mechanism of inhibition of firefly luminescence by local anesthetics.
- Effect of local anesthetics on the electrical characteristics of an excitable model membrane composed of dioleyl phosphate II. Dynamic response.
- Effect of local anesthetics on the electrical characteristics of an excitable model membrane composed of dioleyl phosphate I. Static and steady-state response.
- Effect of inhalation anesthetics on swimming activity of artemia salina.
- Classification of the binding modes in bovine serum albumin using terminally substituted alkane analogues.
- Multi-Unit and Multi-Path system of the neural network can explain the steep dose-response of MAC.
- Myristate, a 14-carbon fatty acid, effectively reverses anesthesia.
- Temperature dependence of thermodynamic activity in volatile anesthetics: correlation between anesthetic potency and activity.
- Action mechanism of water soluble ethanol on phospholipid monolayers using a quartz crystal oscillator.
- Inhibition of firefly luciferase by alkane analogues.
- Preferential partitioning of uncharged local anesthetics into the surface-adsorbed film.
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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West Virginia University -
University of Utah -
Keio Gujuku University School of Medicine
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