Director: Heart Failure and Pulmonary Hypertension Center, Southeastern Cardiology, Columbus, Georgia
Cardiology
Dr. Hunter C. Champion Sr., MD
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Hunter Champion practices Cardiology. He attended Tulane University School of Medicine. He received awards:"CMS Meaningful Use Stage 1 Certification". Dr. Hunter C. Champion Sr. is a published doctor. He has 84 papers published. The most current publication "Effects of acute intravenous iloprost on right ventricular hemodynamics in rats with chronic pulmonary hypertension." Hunter Champion accepts Medicare.
Publications
- Effects of Acute intravenous iloprost on right ventricular hemodynamics in rats with chronic pulmonary hypertension.
- RV-Pulmonary arterial coupling predicts outcome in patients referred for Pulmonary hypertension.
- Structural and Mechanical Adaptations of Right Ventricle Free Wall Myocardium to Pressure Overload.
- Isolated right ventricular dysfunction in patients with human immunodeficiency virus.
- Biocompatibility Assessment of the Levitronix® Centrimag® Adult ECMO Circuit in a Model of Acute Pulmonary Hypertension.
- "Happiness" and stress cardiomyopathy (apical ballooning Syndrome/takotsubo Syndrome).
- Nox-derived ROS are Acutely activated in pressure overload pulmonary hypertension: indications for a seminal role for mitochondrial Nox4.
- Fatty Acid Nitroalkenes Ameliorate Glucose Intolerance and Pulmonary Hypertension in High Fat Diet-Induced Obesity.
- Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model.
- Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell Disease and severe pulmonary arterial hypertension.
- First successful lung transplantation for sickle cell Disease with severe pulmonary arterial hypertension and pulmonary veno-occlusive Disease.
- Sildenafil Promotes eNOS Activation and Inhibits NADPH Oxidase in the Transgenic Sickle Cell Mouse Penis.
- Transforming growth factor-beta signaling promotes Pulmonary hypertension caused by Schistosoma mansoni.
- Hemodynamic predictors of survival in scleroderma-related Pulmonary arterial hypertension.
- Diagnosis and assessment of Pulmonary arterial hypertension.
- Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function.
- Long-acting oral phosphodiesterase inhibition preconditions against reperfusion injury in an experimental lung transplantation model.
- Stress Cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists.
- Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of Pulmonary hypertension.
- Accuracy of Doppler echocardiography in the hemodynamic assessment of Pulmonary hypertension.
- Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.
- Survival in pulmonary hypertension associated with the scleroderma spectrum of Diseases: impact of interstitial lung Disease.
- Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
- Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo.
- PDE5A inhibitor treatment of persistent Pulmonary hypertension after mechanical circulatory support.
- Transcriptomic biomarkers for individual risk assessment in new-onset Heart failure.
- Exposure to inhaled particulate matter impairs cardiac function in senescent mice.
- Hyponatremia predicts right heart failure and poor survival in Pulmonary arterial hypertension.
- Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.
- Mechanisms and potential therapeutic targets for folic acid in cardiovascular Disease.
- Endothelial arginase II: a novel target for the treatment of atherosclerosis.
- Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced Pulmonary hypertension.
- High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury.
- Identification of candidate genes in scleroderma-related Pulmonary arterial hypertension.
- The Heart in scleroderma.
- PDE5A inhibition attenuates bleomycin-induced Pulmonary fibrosis and Pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation.
- New clinical and ultrastructural findings in hydroxychloroquine-induced Cardiomyopathy--a report of 2 cases.
- Phosphodiesterase type 5: expanding roles in cardiovascular regulation.
- Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat.
- Regression of Chronic hypoxic pulmonary hypertension by simvastatin.
- Elevated uric acid levels predict allograft vasculopathy in cardiac transplant recipients.
- Right ventricular failure complicating Heart failure: pathophysiology, significance, and management strategies.
- Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
- Hemolysis in sickle cell mice causes Pulmonary hypertension due to global impairment in nitric oxide bioavailability.
- Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not nor...
- Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction.
- Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase.
- Hemodynamic modulation of endocardial thromboresistance.
- Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
- Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
- Tricuspid annular displacement predicts survival in Pulmonary hypertension.
- Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism.
- Clinical differences between idiopathic and scleroderma-related Pulmonary hypertension.
- eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling.
- Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism.
- Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction.
- Alternatively spliced neuronal nitric oxide synthase mediates penile erection.
- Knockdown of arginase I restores NO signaling in the vasculature of old rats.
- L-arginine therapy in Acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.
- Comparison of the NO and HNO donating properties of diazeniumdiolates: Primary amine adducts release HNO in Vivo.
- In vivo analysis of Chronic phosphodiesterase-5 inhibition with sildenafil in penile erectile tissues: no tachyphylaxis effect.
- Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.
- Decreased exhaled nitric oxide in Pulmonary arterial hypertension: response to bosentan therapy.
- PI3K rescues the detrimental effects of Chronic Akt activation in the heart during ischemia/reperfusion injury.
- Erection capability is potentiated by long-term sildenafil treatment: role of blood flow-induced endothelial nitric-oxide synthase phosphorylation.
- Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B.
- Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from Chronic pressure load.
- Targeting protein phosphatase 1 in Heart failure.
- Conductance catheter-based assessment of arterial input impedance, arterial function, and ventricular-vascular interaction in mice.
- Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy.
- Neurohumoral features of Myocardial stunning due to sudden emotional stress.
- Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
- Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.
- cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
- RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction.
- Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3.
- Calcium handler mishandles Heart.
- Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction.
- Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine Heart: application to study of phospholamban physiology.
- Endothelial dysfunction in erectile dysfunction: role of the endothelium in erectile physiology and Disease.
- Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
- Endothelial dysfunction is present only in the microvasculature and microcirculation of early diffuse systemic sclerosis patients.
- Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+-CaMKII-Regulated Induction of HDAC3.
Schools
Tulane University School Of Medicine
Johns Hopkins Hospital
Procedures Preformed
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
- Cardiac Myocardial Perfusion Imaging
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Conditions Treated
- Angina and Acute Coronary Syndrome
- Aortic Dissection
- Aortic Ectasia
- Aortic Valve Disease
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Johns Hopkins University -
Tulane University School of Medicine
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