Physician
Radiology
Dr. Ian R. Graham, MD
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Ian R. Graham practices Radiology. He went to Creighton University School of Medicine. Creighton University School of Medicine has a rank of 79 in research and a 78 in primary care He has 1 awards "CMS Meaningful Use Stage 1 Certification". Graham is a published doctor and has 44 publications published. The lastest was: 'lambda Rap protein is a structure-specific endonuclease involved in phage recombination.' He is registered with Medicare and accepts Medicare payments.
Publications
- Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle.
- Chronic systemic therapy with low-dose morpholino oligomers ameliorates the pathology and normalizes locomotor behavior in mdx mice.
- Bioinformatic and functional optimization of antisense phosphorodiamidate morpholino oligomers (PMOs) for therapeutic modulation of RNA splicing in muscle.
- Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice.
- Adeno-associated virus-8-mediated intravenous transfer of myostatin propeptide leads to systemic functional improvements of slow but not fast muscle.
- Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene.
- Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer.
- Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration.
- Adenovirus-based targeting in myoblasts is hampered by non-homologous vector integration.
- Human apolipoprotein E expression from mouse skeletal muscle by electrotransfer of nonviral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7).
- ESC/EAS Guidelines for the management of dyslipidaemias The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the Europea...
- European guidelines on cardiovascular disease prevention in clinical practice: executive summary.
- European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and other Societies on Cardiovascular Disease Prevent...
- European guidelines on cardiovascular disease and prevention in clinical practice.
- Rap1p is a negative regulator of the RAP1 gene.
- In vivo analysis of functional regions within yeast Rap1p.
- lambda Rap protein is a structure-specific endonuclease involved in phage recombination.
- A Reb1p-binding site is required for efficient activation of the yeast RAP1 gene, but multiple binding sites for Rap1p are not essential.
- Constitutive expression vectors: PGK.
- Mutually exclusive splicing of calcium-binding domain exons in chick alpha-actinin.
- Rosiglitazone increases fatty acid ?9-desaturation and decreases elongase activity index in human skeletal muscle in vivo.
- ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the Europe...
- Alternative splicing of a human alpha-tropomyosin muscle-specific exon: identification of determining sequences.
- Gene repair validation.
- Oligonucleotide-based gene correction strategies: applications to neuromuscular and cardiovascular diseases.
- Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice.
- Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E.
- Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle.
- Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty.
- Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD).
- Failure to generate atheroprotective apolipoprotein AI phenotypes using synthetic RNA/DNA oligonucleotides (chimeraplasts).
- Screening for antisense modulation of dystrophin pre-mRNA splicing.
- Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisatio...
- Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generatio...
- Stable micro-dystrophin gene transfer using an integrating adeno-retroviral hybrid vector ameliorates the dystrophic pathology in mdx mouse muscle.
- Gene repair and mutagenesis mediated by chimeric RNA-DNA oligonucleotides: chimeraplasty for gene therapy and conversion of single nucleotide polymorphisms (SNPs).
- RNAi-mediated knockdown of dystrophin expression in adult mice does not lead to overt muscular dystrophy pathology.
- Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice.
- Preliminary evaluation of a self-complementary AAV2/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient m...
- Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization.
- Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials.
- Efficient liver-directed gene transfer by in situ generation of retroviral vector from adenoviral templates.
- Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, p...
Schools
Creighton University
Naval Mc
Doctors Specialties
- Diagnostic Radiology
- Radiology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- American Enterprise Group
- American Republic
- Assurant Health
- Benesys
- Commercial Insurance Company
- CoreSource
- Coventry Health Care
- Group Health Cooperative
- HealthFirst
- Humana
- Mail Handlers Benefit Plan (MHBP)
- Medicare MCR
- Medico
- National Elevator
- Principal Life
- United Healthcare
- Wisconsin Physicians Service
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Naval Medical Center -
Creighton University School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1528084464 |
| Last Name Of The Provider | GRAHAM |
| First Name Of The Provider | IAN |
| View All |
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