Professor, Pediatrics, Brown University Program in Medicine
Neonat/Perinatology
Dr. James F. Padbury, MD
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James Padbury works in the field of Neonat/Perinatology. He researched medicine at David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is one of the top medical schools in the US. David Geffen School of Medicine at UCLA has a rank of 13 in research and a 7 in primary care He received 2 awards: "Regional Top Doctor" and "Fellow (FAAP)". James F. Padbury, MD is a published physician. He published 102 publications, including: 'Ontogenesis of beta-adrenergic receptors in the ovine placenta.'
Publications
- Neurobehavior related to epigenetic differences in preterm infants.
- Effects of Placental Transfusion on Neonatal and 18 Month Outcomes in Preterm Infants: A Randomized Controlled Trial.
- Intranasal versus Intraperitoneal Delivery of Human Umbilical Cord Tissue-Derived Cultured Mesenchymal Stromal Cells in a Murine Model of Neonatal Lung Injury.
- Single-Family Room Care and Neurobehavioral and Medical Outcomes in Preterm Infants.
- Maternal Obesity and Gestational Diabetes are Associated with Placental Leptin DNA Methylation.
- Bioinformatic Approach to the Genetics of Preeclampsia.
- Maternal smoking during pregnancy and infant stress response: Test of a prenatal programming hypothesis.
- 50 years ago in the journal of pediatrics: the behavior of the lower esophageal sphincter in infants and its relationship to gastroesophageal regurgitation.
- PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models.
- Neonatal sepsis: An old problem with new insights.
- Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse Model.
- Placental miRNA expression profiles are associated with measures of infant neurobehavioral outcomes.
- Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors.
- Long-term outcome of human cord blood-derived hematopoietic progenitor cells in murine lungs.
- Pathway-based genetic analysis of preterm birth.
- In-vitro Validation of Cytokine Neutralizing Antibodies by Testing with Ovine Mononuclear Splenocytes.
- Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior.
- Neonatal intensive care unit: predictive models for length of stay.
- Efficacy of a Non-Hypercalcemic Vitamin-D2 Derived Anti-Cancer Agent (MT19c) and Inhibition of Fatty Acid Synthesis in an Ovarian Cancer Xenograft Model.
- A bioinformatics approach to preterm birth.
- Placenta-Imprinted Gene Expression Association of Infant Neurobehavior.
- In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Element and Developmentally Related Genes in Human Placenta.
- Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas.
- Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: Implications for fetal pr...
- Na+,K+-ATPase activity and subunit protein expression: ontogeny and effects of exogenous and endogenous steroids on the cerebral cortex and renal cortex of sheep.
- Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells.
- Infant neurobehavioral development.
- Millennium neonatology: building for the future. Introduction.
- miR-16 and miR-21 Expression in the Placenta Is Associated with Fetal Growth.
- Endocrine disruptors, environmental oxygen, epigenetics and pregnancy.
- Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay.
- Inter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis.
- Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta.
- Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice.
- Building for the future of Rhode Island's newborns.
- Fetal effects of psychoactive drugs.
- Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.
- Fate and effects of adult bone marrow cells in lungs of normoxic and hyperoxic newborn mice.
- The role of inter-alpha inhibitor proteins in the diagnosis of neonatal sepsis.
- Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery.
- Beta-adrenergic receptor mediated protection against doxorubicin-induced apoptosis in cardiomyocytes: the impact of high ambient glucose.
- Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model.
- Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction.
- A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes.
- A novel phosphoinositide 3-kinase-dependent pathway for angiotensin II/AT-1 receptor-mediated induction of collagen synthesis in MES-13 mesangial cells.
- Antibody targeting of stem cells to infarcted myocardium.
- Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trial.
- Ontogeny of phosphoinositide 3-kinase signaling in developing heart: effect of acute beta-adrenergic stimulation.
- Virtual reality of stem cell transplantation to repair injured myocardium.
- Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.
- Transcriptional regulation of the LAT-1/CD98 light chain.
- A revised allele frequency estimate and haplotype analysis of the DBH deficiency mutation IVS1+2T --> C in African- and European-Americans.
- Inter-alpha inhibitor proteins in infants and decreased levels in neonatal sepsis.
- Molecular interactions between glucocorticoid and catecholamine signaling pathways.
- Effects of fetal growth retardation on the development of central and peripheral catecholaminergic pathways in the sheep.
- Respiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid. TRH Study Group.
- A controlled trial of insulin infusion and parenteral nutrition in extremely low birth weight infants with glucose intolerance.
- Free and sulfoconjugated catecholamine responses at birth in newborn sheep.
- Cardiovascular effects of SKF 104078 in lambs.
- Single umbilical artery ligation-induced fetal growth retardation: effect on postnatal adaptation.
- Fetal catecholamine, cardiovascular, and neurobehavioral responses to cocaine.
- The role of beta-adrenoreceptor stimulation and contractile state in the preterm lamb's response to altered ductus arteriosus patency.
- Effect of fetal adrenalectomy on catecholamine release and physiologic adaptation at birth in sheep.
- Naloxone potentiates epinephrine release during hypoxia in fetal sheep: dose response and cardiovascular effects.
- Involvement of developing sympathetic nervous system in thyroxine-mediated submandibular gland nerve growth factor and epidermal growth factor responses.
- HE4 (WFDC2) gene overexpression promotes ovarian tumor growth.
- Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity.
- Catecholamine and endorphin responses to delivery in term and preterm lambs.
- Effect of thyroid status on lung and heart beta-adrenergic receptors in fetal and newborn sheep.
- Epidermal growth factor acts as a corticotropin-releasing factor in chronically catheterized fetal lambs.
- Neonatal adaptation: naloxone increases the catecholamine surge at birth.
- The effect of chemical sympathectomy on catecholamine release at birth.
- Sympathoadrenal system activity at birth: integration of postnatal adaptation.
- Thresholds for physiological effects of plasma catecholamines in fetal sheep.
- Effect of fetal thyroidectomy on newborn thermogenesis in lambs.
- Pulmonary clearance of norepinephrine in lambs.
- Fetal catecholamine responses to maternal hypoglycemia.
- Plasma catecholamines and their physiologic thresholds during the first ten days of life in sheep.
- The effects of hypoxia on (methionine) enkephalin peptide and catecholamine release in fetal sheep.
- Pharmacokinetics of dopamine in critically ill newborn infants.
- Effects of amiodarone and desethylamiodarone on rabbit myocardial beta-adrenoceptors and serum thyroid hormones--absence of relationship to serum and myocardial drug c...
- Free and sulfoconjugated catecholamine responses to hypoxia in fetal sheep.
- Hemodynamic and neuroendocrine adaptations of the preterm lamb left ventricle to acutely increased afterload.
- Thresholds for the physiologic effects of adrenergic agents: a methodologic appraisal.
- Functional maturation of the adrenal medulla and peripheral sympathetic nervous system.
- Prolonged beta-agonist infusion does not induce desensitization or down-regulation of beta-adrenergic receptors in newborn sheep.
- Effects of acute oligohydramnios on respiratory system of fetal sheep.
- Intraosseous versus intravenous epinephrine infusions in lambs: pharmacokinetics and pharmacodynamics.
- Dobutamine pharmacokinetics and pharmacodynamics in pediatric intensive care patients.
- Elevated plasma Met-enkephalin levels in the human newborn are a poor indicator of perinatal stress.
- Dobutamine pharmacokinetics and cardiovascular responses in critically ill neonates.
- Ovine fetal renal and hormonal responses to changes in plasma epinephrine.
- Neonatal adaptation: cardiac adrenergic effector mechanisms after birth in newborn sheep.
- Plasma methionine enkephalin levels in the human newborn at birth.
- Differential response of ovine placental lactogen levels in maternal and fetal circulations following single umbilical artery ligation in fetal sheep.
- Metabolic clearance and plasma appearance rates of catecholamines in preterm and term fetal sheep.
- Autoimmune sympathectomy in fetal rabbits.
- Dopamine pharmacokinetics in critically ill newborn infants.
- Neonatal adaptation: greater sympathoadrenal response in preterm than full-term fetal sheep at birth.
- Ontogenesis of beta-adrenergic receptors in the ovine placenta.
- Expression and localization of Inter-alpha Inhibitors in rodent brain.
Schools
University of California At Los Angeles
San Francisco General Hospital
San Francisco General Hospital Med Center
Children39s Hospital Boston
Doctors Specialties
- Neonatal Medicine
- Neonat/Perinatology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (FAAP)
Education
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UCSF -
Boston Children's Hospital -
David Geffen School of Medicine at UCLA
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