Professor of Neurological Surgery, University Alabama
Neurosurgery
Dr. James M. Markert, MD
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James M. Markert works in the field of Neurosurgery. He attended Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a one of the best medicals schools. Columbia University College of Physicians & Surgeons is ranked 8 in research and 52 in primary care medicine He received 4 awards: "Meaningful Use Stage 1 Certification", "Fellow (FAANS)", "Fellow (FACS)" and "Top MD". James Markert has written publications. He has 51 publications published with PubMed. The lastest publication is: 'STAT1 and NFkappaB Inhibitors Diminish Basal Interferon Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST cells.' He is registered with Medicare and accepts Medicare payments.
Publications
- Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses.
- STAT1 and NFkappaB Inhibitors Diminish Basal Interferon Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST cells.
- In Reply: Volumetric Arc Therapy (RapidArc) vs Gamma Knife Radiosurgery for Multiple Brain Metastases.
- Prolonged treatment with bevacizumab is associated with Brain atrophy: a pilot study in patients with high-grade gliomas.
- Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral Nerve sheath tumor cell lines.
- γ134.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxia.
- The History of Neurosurgery at the University of Alabama at Birmingham.
- Comparison of Plan Quality and Delivery Time between Volumetric Arc Therapy (RapidArc) and Gamma Knife Radiosurgery for Multiple Cranial Metastases.
- Evaluation of the Safety and Biodistribution of M032, an Attenuated Herpes Simplex Virus Type 1 Expressing hIL-12, After IntraCerebral Administration to Aotus Nonhuman...
- Phase I Clinical Trial of Intratumoral Reovirus Infusion for the Treatment of Recurrent Malignant Gliomas in Adults.
- A Phase I trial of Oncolytic HSV-1, G207, Given in Combination with Radiation for Recurrent GBM demonstrates Safety and Radiographic Responses.
- Evaluation of the Safety and Biodistribution of M032, an Attenuated HSV-1 Virus Expressing hIL-12, After IntraCerebral Administration to Aotus Non-Human Primates.
- Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid Tumors.
- Viral therapy of glioblastoma multiforme.
- Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy.
- Preclinical evaluation of oncolytic ??(1)34.5 herpes simplex virus expressing interleukin-12 for therapy of breast cancer Brain metastases.
- Human Herpesviridae Methods of Natural Killer Cell Evasion.
- Stereotactic radiosurgical treatment of Brain metastasis of primary tumors that rarely metastasize to the central nervous system.
- Hypoxia Moderates γ(1)34.5-Deleted Herpes Simplex Virus Oncolytic Activity in Human Glioma Xenoline Primary Cultures.
- The Relationship Between INR and Development of Hemorrhage With Placement of Ventriculostomy.
- Meta-Analysis of hemorrhagic complications from Ventriculostomy Placement by Neurosurgeons.
- Ventricular Shunt in Patients with Traumatic Brain Injury.
- Strategies for the rapid construction of conditionally-replicating HSV-1 vectors expressing foreign genes as antiCancer therapeutic agents.
- Preclinical evaluation of ex vivo expanded/activated γδ T cells for immunotherapy of glioblastoma multiforme.
- Risk factors for conversion to permanent ventricular shunt in patients receiving therapeutic ventriculostomy for traumatic Brain injury.
- Acquisition of temozolomide chemoresistance in Gliomas leads to remodeling of mitochondrial electron transport chain.
- A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
- Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111.
- Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma.
- Oncolytic viral therapy of malignant glioma.
- Herpes simplex virus oncolytic therapy for pediatric Malignancies.
- Cancer of the tonsil presenting as central Nervous system metastasis: A case report.
- Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM.
- Hitting a moving target: evolution of a treatment paradigm for atypical Meningiomas amid changing diagnostic criteria.
- Predictors of distant Brain recurrence for patients with newly diagnosed Brain metastases treated with stereotactic radiosurgery alone.
- Effects of G207, a conditionally replication-competent oncolytic herpes simplex virus, on the developing mammalian Brain.
- Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs surv...
- Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells.
- Dexmedetomidine as rescue drug during awake craniotomy for cortical motor mapping and tumor resection.
- Polymerase chain reaction for the rapid detection of Cerebrospinal fluid shunt or ventriculostomy infections.
- Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model.
- Cation selectivity and inhibition of malignant glioma Na+ channels by Psalmotoxin 1.
- Initial treatment of melanoma Brain metastases using gamma knife radiosurgery: an evaluation of efficacy and toxicity.
- Biologic warfare for a good cause: HSV-1 anti-tumor therapy.
- Acid-sensing ion channels in malignant Gliomas.
- Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function.
- Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme.
- Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide.
- Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast Cancer cells.
- Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma.
Schools
Columbia University College Of Physicians and Surgeons
University Mich Med Center
Procedures Preformed
- Cerebrospinal Fluid (CSF) Shunt - Insertion, Repair or Removal
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Dural Repair or Other Spinal Spinal Cord Repair
- Lamina Procedures (incl. Laminectomy, Laminoplasty, Laminotomy)
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Conditions Treated
- Acoustic Neuroma
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Aneurysm
- Brain Cancer
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- Meaningful Use Stage 1 Certification
- Fellow (FAANS)
- Fellow (FACS)
- Top MD
Education
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University of Michigan Hospitals and Health Centers -
Columbia University College of Physicians & Surgeons
Hospital
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University of Alabama Hospital -
Birmingham Veterans Affairs Medical Center
Drug Facts
| NPI NUMBER | 1760413645 | |
| NPPES Provider LastName | MARKERT | |
| NPPES Provider FirstName | JAMES | |
| NPPES Provider ZIPCode | 35233 | |
| NPPES Provider State | AL | |
| Specialty Description | Neurosurgery | |
| Total Claim Count | 77.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1760413645 |
| Last Name Of The Provider | MARKERT |
| First Name Of The Provider | JAMES |
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