Physician
Internal Medicine
Dr. James M. Pluda, MD
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James Pluda is an expert in the field of Internal Medicine. James M. Pluda, MD is a published doctor and has 88 publications published. The lastest was: 'Pharmacokinetics of thalidomide in an elderly prostate cancer population.'
Publications
- Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
- Treatment of AIDS-related Kaposi's sarcoma with interleukin-12: rationale and preliminary evidence of clinical activity.
- Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.
- Factors involved in the pharmacokinetics of COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer: clinical and experimental studies.
- Using positron emission tomography 2-deoxy-2-[18F]fluoro-D-glucose, 11CO, and 15O-water for monitoring androgen independent prostate cancer.
- A pilot study of cidofovir in patients with kaposi sarcoma.
- Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study.
- Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck.
- Approaches to preclinical screening of antiangiogenic agents.
- New targets for cancer chemotherapy.
- A randomized phase II trial of docetaxel (taxotere) plus thalidomide in androgen-independent prostate cancer.
- A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer.
- Thalidomide neuropathy in patients treated for metastatic prostate cancer.
- A phase I trial of carboxyamido-triazole and paclitaxel for relapsed solid tumors: potential efficacy of the combination and demonstration of pharmacokinetic interaction.
- Drug-induced lupus associated with COL-3: report of 3 cases.
- Reversible sideroblastic anemia associated with the tetracycline analogue COL-3.
- Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer.
- Clinical trial designs for cytostatic agents: are new approaches needed?
- Clinical trials referral resource. Current clinical trials administering the antiangiogenesis agent SU5416.
- Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
- Phase II evaluation of thalidomide in patients with metastatic breast cancer.
- Activity of thalidomide in AIDS-related Kaposi's sarcoma.
- High-performance liquid chromatography with mass spectrometry detection for quantitating COL-3, a chemically modified tetracycline, in human plasma.
- Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas.
- Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay.
- A pharmacokinetically guided Phase II study of carboxyamido-triazole in androgen-independent prostate cancer.
- O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair.
- Pharmacokinetics of thalidomide in an elderly prostate cancer population.
- Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.
- The challenge of designing clinical trials for AIDS-related Kaposi's sarcoma.
- Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma.
- Phase I study of bryostatin 1 in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia.
- Development of angiogenesis inhibitors for cancer therapy.
- New drugs in non-Hodgkin''s lymphoma.
- Promising new agents under development by the Division of Cancer Treatment, Diagnosis, and Centers of the National Cancer Institute.
- Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies.
- Effect of combination therapy with zidovudine and didanosine on neuropsychological functioning in patients with symptomatic HIV disease: a comparison of simultaneous a...
- The pharmacokinetics of TNP-470, a new angiogenesis inhibitor.
- A phase I study of pentosan polysulfate sodium in patients with advanced malignancies.
- Clinical trials referral resource. Clinical trials using thalidomide.
- AIDS-related Kaposi's sarcoma. A template for the translation of molecular pathogenesis into targeted therapeutic approaches.
- Clinical trials referral resource. Clinical trials of suramin.
- Clinical trials referral resource. Clinical trials using bryostatin-1.
- Clinical implications of tumor-associated neovascularization and current antiangiogenic strategies for the treatment of malignancies of pancreas.
- Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (--)-2'',3''-dideoxy-3''-thiacytidine.
- A pilot study of sequential therapy with zidovudine plus acyclovir, dideoxyinosine, and dideoxycytidine in patients with severe human immunodeficiency virus infection.
- Noncytotoxic approaches to the treatment of HIV-associated Kaposi's sarcoma.
- Parameters affecting the development of non-Hodgkin's lymphoma in patients with severe human immunodeficiency virus infection receiving antiretroviral therapy.
- Assay of the antiangiogenic compound TNP-470, and one of its metabolites, AGM-1883, by reversed-phase high-performance liquid chromatography in plasma.
- Clinical development of anticancer agents from natural products.
- A randomized pilot study of alternating or simultaneous zidovudine and didanosine therapy in patients with symptomatic human immunodeficiency virus infection.
- A phase I/II study of 2'-deoxy-3'-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection.
- Five-year follow-up of a phase I study of didanosine in patients with advanced human immunodeficiency virus infection.
- Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.
- Administration of pentosan polysulfate to patients with human immunodeficiency virus-associated Kaposi's sarcoma.
- Phase I/II study of intermittent all-trans-retinoic acid, alone and in combination with interferon alfa-2a, in patients with epidemic Kaposi's sarcoma.
- Treatment of HIV-associated Kaposi''s sarcoma with paclitaxel.
- Primary lymphoma of the liver in a patient with acquired immune deficiency syndrome and chronic hepatitis B.
- In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine.
- Thin-walled cavities, cysts, and pneumothorax in Pneumocystis carinii pneumonia: further observations with histopathologic correlation.
- Widespread visceral calcifications in disseminated Pneumocystis carinii infection: CT characteristics.
- For HIV patients survival increases the risk of lymphoma.
- Treatment of acquired immunodeficiency syndrome.
- Subcutaneous recombinant granulocyte-macrophage colony-stimulating factor used as a single agent and in an alternating regimen with azidothymidine in leukopenic patien...
- Quantitative analysis of HIV-1 proviral DNA in peripheral blood mononuclear cells from patients with AIDS or ARC: decrease of proviral DNA content following treatment ...
- Pharmacokinetics of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine in patients with severe human immunodeficiency virus infection.
- Initial clinical experience with dideoxynucleosides as single agents and in combination therapy.
- Projections of the incidence of non-Hodgkin's lymphoma related to acquired immunodeficiency syndrome.
- Long-term toxicity/activity profile of 2'',3''-dideoxyinosine in AIDS or AIDS-related complex.
- The National Cancer Institute phase I study of 2',3'-dideoxyinosine administration in adults with AIDS or AIDS-related complex: analysis of activity and toxicity profi...
- Development of non-Hodgkin lymphoma in a cohort of patients with severe human immunodeficiency virus (HIV) infection on long-term antiretroviral therapy.
- Therapy of AIDS and AIDS-related tumors.
- Pharmacokinetics of 2',3'-dideoxyinosine in patients with severe human immunodeficiency infection. II. The effects of different oral formulations and the presence of o...
- HIV-associated non-Hodgkin''s lymphomas.
- Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future.
- Hematologic effects of AIDS therapies.
- CD4 count and the risk for death in patients infected with HIV receiving antiretroviral therapy.
- The occurrence of opportunistic non-Hodgkin''s lymphomas in the setting of infection with the human immunodeficiency virus.
- Plasma HIV-1 viremia in HIV-1 infected individuals assessed by polymerase chain reaction.
- Pneumocystis carinii and Mycobacterium avium-intracellulare infection of the choroid.
- Visceral calcifications in patients with AIDS.
- Therapy of AIDS and AIDS-associated neoplasms.
- Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin.
- Phase I study of recombinant human endostatin in patients with advanced solid tumors.
- Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.
- Phase I and pharmacokinetic study of a micronized formulation of carboxyamidotriazole, a calcium signal transduction inhibitor: toxicity, bioavailability and the effec...
- Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumors.
Schools
Rosalind Franklin University of Medicine and Science Chicago Medical School
Doctors Specialties
- Medical Oncology
- Oncology
- Internal Medicine
Accepted Insurances
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