Professor, Ophthalmology, Loyola University Chicago Stritch School of Medicine
Anesthesiology
Dr. James McDonnell, MD
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James McDonnell works in the field of Anesthesiology. James McDonnell is also a published doctor. He has 43 publication published. The most recent publication is: Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus. James McDonnell is registered with Medicare and accepts Medicare payments.
Publications
- MDM2-p53 protein-protein interaction inhibitors: a-ring substituted isoindolinones.
- Structural and functional studies on the N-terminal domain of the Shigella type III secretion protein MxiG.
- Basis of the intrinsic flexibility of the C?3 domain of IgE.
- Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI.
- Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
- Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency.
- Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complement.
- Inhibitors of MDM2 and MDMX: a structural perspective.
- Analysis of chemical shift changes reveals the binding modes of isoindolinone inhibitors of the MDM2-p53 interaction.
- Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55.
- The intrinsic flexibility of IgE and its role in binding FcepsilonRI.
- Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.
- Direct analysis of a GPCR-agonist interaction by surface plasmon resonance.
- NMR determination that an extended BH3 motif of pro-apoptotic BID is specifically bound to BCL-XL.
- Catalytic folding of the Cepsilon3 domain by its high affinity receptor.
- The structure of human CD23 and its interactions with IgE and CD21.
- Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide.
- The key role of protein flexibility in modulating IgE interactions.
- Screening and optimizing protein production in E. coli.
- Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases.
- Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.
- Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition.
- The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha.
- Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes...
- Specificity and binding kinetics of murine lupus anti-DNA monoclonal antibodies implicate different stimuli for their production.
- Conformation of the isolated cepsilon3 domain of IgE and its complex with the high-affinity receptor, FcepsilonRI.
- Cross-reactivity of antiidiotypic antibodies with DNA in systemic lupus erythematosus.
- BCL-2 family members and the mitochondria in apoptosis.
- Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists.
- Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus.
- Identification of contact residues in the IgE binding site of human FcepsilonRIalpha.
- Participation of the N-terminal region of Cepsilon3 in the binding of human IgE to its high-affinity receptor FcepsilonRI.
- Peptide analogs that inhibit IgE-Fc epsilon RI alpha interactions ameliorate the development of lethal graft-versus-host disease.
- Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI.
- Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides.
- Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor.
- Calreticulin binding affinity for glycosylated laminin.
- A rationally designed CD4 analogue inhibits experimental allergic encephalomyelitis.
- Keratitis as a complication of bilateral, simultaneous radial keratotomy.
- Direct involvement of the CDR3-like domain of CD4 in T helper cell activation.
- Percutaneous bone marrow grafting of delayed union and nonunion in cancer patients.
- Changing indications for penetrating keratoplasty, 1984-1988.
Schools
Des Moines University College Of Osteopathic Med Des Moines Ia
Suburban General Hospital
Philadelphia College Of Osteopathic Med
Procedures Preformed
- Nerve Block, Somatic
- Non-Spinal Nerve Blocks
Conditions Treated
- Chronic Pelvic Pain
- Headache
- Migraine
Doctors Specialties
- Pain Medicine
- Anesthesiology
Accepted Insurances
- Bakery & Confectionary Union Plan
- Commercial Insurance Company
- GEHA
- HealthSmart
- Humana
- Medicare MCR
- Meritain Health
- United Healthcare
- Universal American
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1962407304 |
| Last Name Of The Provider | MCDONNELL |
| First Name Of The Provider | JAMES |
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