Physician
General Surgery
Dr. James W. Dennis, MD
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James Dennis practices General Surgery. He went to Indiana University School of Medicine. Indiana University School of Medicine is ranked 45/47 in Research/PrimaryCare. He received 1 awards: "Fellow (FACS)". James Dennis is also published. He has 101 publications published. The lastest publication: "Inhibitors of carbohydrate processing: A new class of anticancer agents.' James Dennis accepts Medicare.
Publications
- Fractionation and characterization of rat liver poly(A)-containing RNA.
- CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency.
- Carcinogenicity of tumor cell populations: origin of a putative H-2 isoantigenic loss variant tumor.
- Anastomotic pseudoAneurysms. A continuing late complication of vascular reconstructive procedures.
- Adoptive immune therapy in mice bearing poorly immunogenic metastases, using T lymphocytes stimulated in vitro against highly immunogenic mutant sublines.
- Tumor cell surface carbohydrate and the metastatic phenotype.
- Asn-linked oligosaccharides in lectin-resistant tumor-cell mutants with varying metastatic potential.
- Macrophage/biomaterial interactions: the stimulation of endothelialization.
- Biosynthesis of Aedes aegypti lipophorin and gene expression of its apolipoproteins.
- Purification of two glycoproteins expressing beta 1-6 branched Asn-linked oligosaccharides from metastatic tumour cells.
- CMP-N-acetylneuraminic acid hydroxylase activity determines the wheat germ agglutinin-binding phenotype in two mutants of the lymphoma cell line MDAY-D2.
- Secondary Vascular procedures with polytetrafluoroethylene grafts for lower extremity ischemia in a male veteran population.
- Membrane-associated alterations detected in poorly tumorigenic lectin-resistant variant sublines of a highly malignant and metastatic murine tumor.
- Phenotypic and genotypic differences between high- and low-metastatic related tumor lines and the problem of tumor progression and variant generation.
- Imaging stem cell differentiation for cell-based tissue repair.
- Partial reversion of the metastatic phenotype in a wheat germ agglutinin-resistant mutant of the murine tumor cell line MDAY-D2 selected with Bandeiraea simplicifolia ...
- Surface sialic acid reduces attachment of metastatic tumour cells to collagen type IV and fibronectin.
- Measuring swainsonine in serum of cancer patients: phase I clinical trial.
- Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation.
- The relationship between neointimal fibrous hyperplasia and distal anastomotic angles in Vein bypass grafts.
- Superiority of end-diastolic volume and ejection fraction measurements over wedge pressures in evaluating cardiac function during Aortic reconstruction.
- A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors.
- Constitutive expression and secretion of proteases in non-metastatic SP1 mammary carcinoma cells and its metastatic sublines.
- Overexpression of the alpha2,6-sialyltransferase, ST6Gal I, in a low metastatic variant of a murine lymphoblastoid cell line is associated with appearance of a unique ...
- Tumor progression in metastasis: an experimental approach using lectin resistant tumor variants.
- Different patterns of lectin binding and cell surface sialylation detected on related high- and low-metastatic tumor lines.
- An exoglycosidase-sensitive triggering site on NK cells which is coupled to transmethylation of membrane phospholipids.
- Genotypic and phenotypic evolution of a murine tumor during its progression in vivo toward metastasis.
- Different metastatic phenotypes in two genetic classes of wheat germ agglutinin-resistant tumor cell mutants.
- Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.
- Demonstration of a correlation between tumor cell H-2 antigen content, immunogenicity, and tumorigenicity using lectin-resistant tumor variants.
- Characterization of a deficiency in fucose metabolism in lectin-resistant variants of a murine tumor showing altered tumorigenic and metastatic capacities in vivo.
- Recognition of asparagine-linked oligosaccharides on murine tumor cells by natural killer cells.
- Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2.
- Relevance of spontaneous in vivo tumor-host cell fusion to tumor progression and metastasis evaluated using a series of lectin-resistant mutant tumor sublines.
- Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.
- Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia.
- Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies.
- Asparagine-linked oligosaccharides in malignant tumour growth.
- Inhibitors of carbohydrate processing: A new class of anticancer agents.
- Core 2 GlcNAc-transferase and polylactosamine expression in O-glycans.
- Asn-linked oligosaccharide processing and malignant potential.
- Evidence that beta 1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes.
- Regarding "Adverse outcome of nonoperative management of intimal injuries caused by penetrating trauma".
- Asparagine-linked oligosaccharides associated with metastatic cancer.
- Basement membrane invasion by first trimester human trophoblast: requirement for branched complex-type Asn-linked oligosaccharides.
- Altered expression of leucocyte sialoglycoprotein in Wiskott-Aldrich Syndrome is associated with a specific defect in O-glycosylation.
- Carbonoyloxy analogs of the anti-metastatic drug swainsonine. Activation in tumor cells by esterases.
- Autocrine and paracrine regulation of tissue inhibitor of metalloproteinases, transin, and urokinase gene expression in metastatic and nonmetastatic mammary carcinoma ...
- N-linked oligosaccharide processing and tumor cell biology.
- Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue.
- A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis.
- The Internet and education in surgery.
- Quality control of resident operative experience: compliance with RRC criteria.
- Effects of swainsonine and polyinosinic:polycytidylic acid on murine tumor cell growth and metastasis.
- A phase I study of swainsonine in patients with advanced malignancies.
- Identification of asparagine-linked oligosaccharides involved in tumor cell adhesion to laminin and type IV collagen.
- Spontaneous fusion in vivo between normal host and tumor cells: possible contribution to tumor progression and metastasis studied with a lectin-resistant mutant tumor.
- Inhibition of human HT29 colon carcinoma growth in vitro and in vivo by swainsonine and human interferon-alpha 2.
- Oncogenes conferring metastatic potential induce increased branching of Asn-linked oligosaccharides in rat2 fibroblasts.
- Tumor cell surface beta 1-4-linked galactose binds to lectin(s) on microVascular endothelial cells and contributes to organ colonization.
- Growth inhibition of human melanoma tumor xenografts in athymic nude mice by swainsonine.
- Molecular characterization of P2B/LAMP-1, a major protein target of a metastasis-associated oligosaccharide structure.
- Asparagine-linked oligosaccharides in murine tumor cells: comparison of a WGA-resistant (WGAr) nonmetastatic mutant and a related WGA-sensitive (WGAs) metastatic line.
- Oncodevelopmental expression of--GlcNAc beta 1-6Man alpha 1-6Man beta 1--branched asparagine-linked oligosaccharides in murine tissues and human breast carcinomas.
- Tn antigen and UDP-Gal:GalNAc alpha-R beta 1-3Galactosyltransferase expression in human breast carcinoma.
- Nonoperative observation of clinically occult Arterial injuries: a prospective evaluation.
- Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells.
- Efficacy of Deep venous thrombosis prophylaxis in trauma patients and identification of high-risk groups.
- Changing patterns of Arterial injuries associated with fractures and dislocations.
- Isolation and characterization of spontaneous wheat germ agglutinin-resistant human melanoma mutants displaying remarkably different metastatic profiles in nude mice.
- Branching N-linked oligosaccharides in breast cancer.
- Inhibition of N-linked oligosaccharide processing in tumor cells is associated with enhanced tissue inhibitor of metalloproteinases (TIMP) gene expression.
- Branching beta 1-6N-acetylglucosaminetransferases and polylactosamine expression in mouse F9 teratocarcinoma cells and differentiated counterparts.
- N-linked oligosaccharide processing and autocrine stimulation of tumor cell proliferation.
- Sialylation and malignant potential in tumour cell glycosylation mutants.
- A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research.
- Complex asparagine-linked oligosaccharides in Mgat1-null embryos.
- Prophylactic Greenfield filter placement in selected high-risk trauma patients.
- Characterization of O-linked oligosaccharide biosynthesis in cultured cells using paranitrophenyl alpha-D-GalNAc as an acceptor.
- Long-term follow-up of prophylactic greenfield filters in multisystem trauma patients.
- The extent of polylactosamine glycosylation of MDCK LAMP-2 is determined by its Golgi residence time.
- Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice.
- Overexpression of core 2 N-acetylglycosaminyltransferase enhances cytokine actions and induces hypertrophic myocardium in transgenic mice.
- Aberrant O-linked oligosaccharide biosynthesis in lymphocytes and platelets from patients with the Wiskott-Aldrich Syndrome.
- Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich Syndrome (WAS).
- Biogenesis of multilamellar bodies via autophagy.
- STAT1 and STAT3 alpha/beta splice form activation predicts host responses in mouse hepatitis virus type 3 infection.
- Suppression of tumor growth and metastasis in Mgat5-deficient mice.
- Regulation of BMP-induced ectopic bone formation by Ahsg.
- Protein glycosylation in development and Disease.
- Antisense and sense cDNA expression cloning using autonomously replicating vectors and toxic lectin selection.
- Glycosylation-dependent collagen-binding activities of two membrane glycoproteins in MDAY-D2 tumor cells.
- Beta 1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia.
- New perspectives on the management of penetrating trauma in proximity to major limb arteries.
- Glycoprotein glycosylation and cancer progression.
- Physical examination alone is safe and accurate for evaluation of Vascular injuries in penetrating Zone II neck trauma.
- Are arteriograms necessary in penetrating zone II neck injuries?
- Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation.
- Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.
Schools
Indiana University School Of Medicine
Loyola University Med Center
Loyola University
Procedures Preformed
- Aortic Repair, Open or Repair of Arterial Aneurysm, Open
- Arteriovenous Shunt Creation
- Carotid Endarterectomy (CEA) or Excision of Infected Graft
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
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Conditions Treated
- Abdominal Aortic Aneurysm (AAA)
- Acute Deep Vein Thrombosis (DVT)
- Acute Venous Embolism Thrombosis
- Aortic Aneurysm
- View All
Doctors Specialties
- Critical Care Surgery
- General Surgery
Accepted Insurances
Awards
- Fellow (FACS)
Education
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Loyola University -
Indiana University School of Medicine
Hospital
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UF Health Jacksonville
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