Professor, Medicine, University of Washington School of Medicine
Endocrinology
Dr. Jay W. Heinecke, MD
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Heinecke works in the field of Endocrinology. He received awards:"Elected Member". Jay W. Heinecke is also published. He has 18 publications published. The lastest publication: "Niacin Therapy Increases High-Density Lipoprotein Particles and Total Cholesterol Efflux Capacity But Not ABCA1-Specific Cholesterol Efflux in Statin-Treated Subjects.'
Publications
- Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway.
- Niacin Therapy Increases High-Density Lipoprotein Particles and Total Cholesterol Efflux Capacity But Not ABCA1-Specific Cholesterol Efflux in Statin-Treated Subjects.
- Hematopoietic ABCA1 deletion promotes monocytosis and worsens diet-induced insulin resistance in mice.
- Parallel reaction monitoring (PRM) and selected reaction monitoring (SRM) exhibit comparable linearity, dynamic range and precision for targeted quantitative HDL prote...
- An Experimentally Robust Model of Monomeric Apolipoprotein A-I Created from a Chimera of Two X-ray Structures and Molecular Dynamics Simulations.
- Quantification of HDL Particle Concentration by Calibrated Ion Mobility Analysis.
- Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: An additional proatherogenic mechanism in systemic lupus erythematosus.
- Humans with Atherosclerosis have Impaired ABCA1 Cholesterol Efflux and Enhanced HDL Oxidation by Myeloperoxidase.
- Translation of High-Density Lipoprotein Function Into Clinical Practice: Current Prospects and Future Challenges.
- Resident Renal Mononuclear Phagocytes Comprise Five Discrete Populations with Distinct Phenotypes and Functions.
- HDL's Protein Cargo: Friend or Foe in Cardioprotection?
- High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.
- Cholesterol Accumulation Regulates Expression of Macrophage Proteins Implicated in Proteolysis and Complement Activation.
- Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity.
- Unique proteomic signatures distinguish macrophages and dendritic cells.
- CD36 regulates oxidative stress and inflammation in hypercholesterolemic CKD.
- TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury.
Schools
Washington Center School of Medicine
University of Washington
Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- Elected Member
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