Instructor, Pathology and Immunology, Washington University School of Medicine

Pathology

Dr. Jeffery M. Klco, MD

Jeffery Klco practices Pathology. He studied medicine at Washington University School of Medicine in St. Louis. Dr. Jeffery M. Klco is a published doctor. He has 29 papers published. The most current publication "Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML."

Publications

Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.
Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro.
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation.
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
Notch signaling in acute promyelocytic leukemia.
Genomic impact of transient low-dose decitabine treatment on primary AML cells.
Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: A phase I study.
Immunohistochemical analysis of monocytic leukemias: usefulness of CD14 and Kruppel-like factor 4, a novel monocyte marker.
Use of whole-genome sequencing to diagnose a cryptic fusion oncogene.
Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression.
Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.
Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells.
Molecular pathology of myeloproliferative neoplasms.
Bone marrow biopsy in patients with hepatitis C virus infection: spectrum of findings and diagnostic utility.
The spectrum of adult B-lymphoid leukemias with BCR-ABL: molecular diagnostic, cytogenetic, and clinical laboratory perspectives.
Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling.
Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop.
Essential role for the second extracellular loop in C5a receptor activation.
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.
pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development.
C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor.
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways.
Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.
State of the art in myeloid sarcoma.
Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma.
Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence.

Schools

Washington Univ Sch Of Med

Doctors Specialties

Hematology
Hematopathology
Pathology

Accepted Insurances

Blue Card PPO
Network S
Choice Plus POS
Navigate HMO
Navigate POS
Options PPO

Education

Washington University
Washington University School of Medicine in St. Louis

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