Professor and Head
Neurology
Dr. Jeffrey A. Loeb, MD
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Jeffrey A. Loeb, MD is an expert in the field of Neurology. He studied medicine at University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10/19 in Research/PrimaryCare. Dr. Jeffrey A. Loeb is also published. He has 57 publications published. The lastest publication: "Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development.'
Publications
- Neocortical slices from adult chronic epileptic rats exhibit Discharges of higher voltages and broader spread.
- IntraCranial EEG analysis in tumor-related epilepsy: Evidence of distant epileptic abnormalities.
- Coalescence of deep and superficial epileptic foci into larger Discharge units in adult rat neocortex.
- Predicting novel histopathological microlesions in human epileptic Brain through transcriptional clustering.
- Neurocysticercosis: A natural human model of epileptogenesis.
- Enhanced slow waves at the periphery of human epileptic foci.
- Systems biology of human epilepsy applied to patients with Brain tumors.
- Complexity of trophic factor signaling in experimental autoimmune encephalomyelitis: Differential expression of neurotrophic and gliotrophic factors.
- The tanapoxvirus 15L protein is a virus-encoded neuregulin that promotes viral replication in human endothelial cells.
- Layer-Specific CREB Target Gene Induction in Human Neocortical Epilepsy.
- Electrical, molecular and behavioral effects of interictal spiking in the rat.
- Aberrant neuregulin 1 signaling in amyotrophic lateral Sclerosis.
- High inter-reviewer variability of spike detection on intraCranial EEG addressed by an automated multi-channel algorithm.
- Critical Period of Axoglial Signaling between Neuregulin-1 and Brain-Derived Neurotrophic Factor Required for Early Schwann Cell Survival and Differentiation.
- Following nerve Injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.
- Identifying targets for preventing epilepsy using Systems biology.
- Neuregulin-ErbB signaling promotes microglial proliferation and chemotaxis contributing to microgliosis and pain after peripheral nerve Injury.
- Targeting human epidermal growth factor receptor signaling with the neuregulin's heparin-binding domain.
- Neurotrophins induce neuregulin release through protein kinase Cdelta activation.
- Focal reduction of neuronal glutamate transporters in human neocortical Epilepsy.
- Neuroprotection and repair by neurotrophic and gliotrophic factors in Multiple sclerosis.
- Activity-dependent gene expression correlates with interictal spiking in human neocortical Epilepsy.
- NT-3 and CNTF exert dose-dependent, pleiotropic effects on cells in the immature dorsal root ganglion: neuregulin-mediated proliferation of progenitor cells and neuron...
- A common pattern of persistent gene activation in human neocortical epileptic foci.
- Neuregulin-1 type III determines the ensheathment fate of axons.
- Specific structural features of heparan sulfate proteoglycans potentiate neuregulin-1 signaling.
- Development of an autocrine neuregulin signaling loop with malignant transformation of human breast epithelial cells.
- Synergistic effects of neuregulin and agrin on muscle acetylcholine receptor expression.
- Rapid axoglial signaling mediated by neuregulin and neurotrophic factors.
- Asymmetric flaccid paralysis: a neuromuscular presentation of West Nile virus infection.
- Neuregulin: an activity-dependent synaptic modulator at the neuromuscular junction.
- Neuregulin expression at neuromuscular synapses is modulated by synaptic activity and neurotrophic factors.
- The human Pim-1 gene is selectively transcribed in different hemato-lymphoid cell lines in spite of a G + C-rich housekeeping promoter.
- Fibroblast growth factors stimulate protein tyrosine phosphorylation and mitogen-activated protein kinase activity in primary cultures of hippocampal neurons.
- The chicken receptor for endocytosis of glycoproteins contains a cluster of N-acetylglucosamine-binding sites.
- Major and minor forms of the rat liver asialoglycoprotein receptor are independent galactose-binding proteins. Primary structure and glycosylation heterogeneity of min...
- Conformational changes in the chicken receptor for endocytosis of glycoproteins. Modulation of ligand-binding activity by Ca2+ and pH.
- Treatment of neurocysticercosis: current status and future research needs.
- Calcific neurocysticercosis and epileptogenesis.
- Functional improvement in a patient with Cerebral calcinosis using a bisphosphonate.
- A novel unsupervised spike sorting algorithm for intraCranial EEG.
- Compressed EEG pattern analysis for critically ill neurological-neurosurgical patients.
- The role of neuregulin (ARIA) at the neuromuscular junction.
- An animal model to study the clinical significance of interictal spiking.
- ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain.
- Neuregulin stimulates DNA synthesis in embryonic chick heart cells.
- Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development.
- Neurotrophic factors increase neuregulin expression in embryonic ventral spinal cord neurons.
- The neuregulin precursor proARIA is processed to ARIA after expression on the cell surface by a protein kinase C-enhanced mechanism.
- Neuregulin-heparan-sulfate proteoglycan interactions produce sustained erbB receptor activation required for the induction of acetylcholine receptors in muscle.
- Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells.
- Pica-associated Cerebral edema in an adult.
- Brain calcifications induce neurological dysfunction that can be reversed by a bone drug.
- Neuregulins: versatile growth and differentiation factors in nervous system development and human Disease.
- Differential distribution of neuregulin in human Brain and spinal fluid.
- Electrospinning of matrigel to deposit a basal lamina-like nanofiber surface.
Schools
University of Chicago
Procedures Preformed
- EEG (Electroencephalogram)
- EMG (Electromyography)
Conditions Treated
- Alzheimer's Disease
- Ataxia
- Autonomic Disorders
- Bell's Palsy
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Doctors Specialties
- Neurology
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Chicago Pritzker School of Medicine
Hospital
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University of Illinois Hospital & Health Sciences System
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