Associate Professor, Medicine - Gastroenterology and Hepatology, Stanford University Medical Center
Gastroenterology
Dr. Jeffrey Glenn, MD
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Jeffrey Glenn practices Gastroenterology. He attended University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is a top medical college. University of California San Francisco School of Medicine has a rank of 3 in research and a 3 in primary care He received 1 awards: "Elected Member". Jeffrey Glenn has written publications. He has 71 publications published with PubMed. The lastest publication is: 'Use of a prenylation inhibitor as a novel antiviral agent.' He is registered with Medicare.
Publications
- Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial.
- Sofosbuvir and simeprevir combination therapy in the setting of liver transplantation and hemodialysis.
- Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A Ligand and Mediates Replication of the Viral Genome.
- HCV NS5A Inhibitors: The Devil Is in the Details.
- Fialuridine Induces Acute Liver Failure in Chimeric TK-NOG Mice: A Model for Detecting Hepatic Drug Toxicity Prior to Human Testing.
- The stanford institute for chemical biology.
- Coinfection with Hepatitis B and D: Epidemiology, Prevalence and Disease in Patients in Northern California.
- The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA.
- Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction.
- Structural Map of a MicroRNA-122:HCV Complex.
- Simplified RNA secondary structure mapping by automation of SHAPE data analysis.
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons.
- The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein.
- Role for ADP ribosylation factor 1 in the regulation of hepatitis C virus replication.
- Hydrophobic nanoparticles improve permeability of cell-encapsulating poly(ethylene glycol) hydrogels while maintaining patternability.
- Mixing the right hepatitis C inhibitor cocktail.
- The Future of HCV Therapy: NS4B as an Antiviral Target.
- Prevalence, correlates, and viral dynamics of hepatitis delta among injection drug users.
- The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors.
- Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate Systems.
- Identification of a class of HCV inhibitors directed against the nonstructural protein NS4B.
- Mechanism of an amphipathic alpha-helical peptide's antiviral activity involves size-dependent virus particle lysis.
- The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation.
- The effect of donor race on the survival of Black Americans undergoing liver transplantation for chronic hepatitis C.
- Alpha-helical peptide-induced vesicle rupture revealing new insight into the vesicle fusion process as monitored in situ by quartz crystal microbalance-dissipation and...
- The evolution of the major hepatitis C genotypes correlates with clinical response to interferon therapy.
- Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide.
- Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis.
- Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells.
- A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals.
- Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells.
- The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection.
- TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication.
- Hepatitis d.
- Creation of lipid partitions by deposition of amphipathic viral peptides.
- A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication.
- Employing two different quartz crystal microbalance models to study changes in viscoelastic behavior upon transformation of lipid vesicles to a bilayer on a gold surface.
- Employing an amphipathic viral peptide to create a lipid bilayer on Au and TiO2.
- Binding dynamics of hepatitis C virus' NS5A amphipathic peptide to cell and model membranes.
- The Power of silence: application of small interfering RNAs to gastroIntestinal diseases.
- Molecular virology of the hepatitis C virus: implication for novel therapies.
- Novel therapies for hepatitis C virus based on lessons from virology.
- Hepatitis C virus core protein associates with detergent-resistant membranes distinct from classical plasma membrane rafts.
- An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replic...
- A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication.
- Overdependence on the host-an Achilles' heel of HCV?
- Testing antivirals against hepatitis delta virus: farnesyl transferase inhibitors.
- In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus.
- Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication.
- A prenylation inhibitor prevents production of infectious hepatitis delta virus particles.
- Effects of hemagglutinin fusion peptide on poly(ethylene glycol)-mediated fusion of phosphatidylcholine vesicles.
- Randomized efficacy trials of long-acting oxytetracycline in neonatal pigs.
- Delivery of macromolecules into cells expressing a viral membrane fusion protein.
- Lessons in defense: hepatitis C, a case study.
- Delivery of liposome-encapsulated RNA to cells expressing influenza virus hemagglutinin.
- Replication of monomeric genomic delta RNA in cultured cells.
- Prenylation of HDAg and antiviral drug development.
- Identification of a prenylation site in delta virus large antigen.
- Novel targets of anti-hepatitis delta virus therapy.
- trans-dominant inhibition of human hepatitis delta virus genome replication.
- In vitro-synthesized hepatitis delta virus RNA initiates genome replication in cultured cells.
- Sustained survival of human hepatocytes in mice: A model for in vivo infection with human hepatitis B and hepatitis delta viruses.
- Use of a prenylation inhibitor as a novel antiviral agent.
- Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel.
- Prenylation inhibitors: a novel class of antiviral agents.
- The reliable targeting of specific drug release profiles by integrating arrays of different albumin-encapsulated microsphere types.
- A small molecule inhibits HCV replication and alters NS4B''s subcellular distribution.
- Transdifferentiation of adipose-derived stem cells into hepatocytes: a new approach.
- Mechanisms of HCV survival in the host.
- Development of novel therapies for hepatitis C.
Schools
University of California At San Francisco
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
Conditions Treated
- Anemia
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
- Diaphragmatic and-or Hiatal Hernia
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Doctors Specialties
- Gastroenterology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- Advantage Preferred DirectAccess Plus PPO
- Blue Cross Blue Shield of California PPO
- Select PPO
- Access Plus Savenet
- Basic Exclusive PPO for Small Business
- Basic PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- First Health (Coventry Health Care) PPO
- Covered California - Bronze PPO
- Health Net PPO
- Individual and Family PPO
- Medicare MCR
- Kaiser PHCS Network PPO
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- PacifiCare HMO
Awards
- Elected Member
Education
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Stanford University -
University of California San Francisco School of Medicine
Hospital
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VA Palo Alto Health Care System -
Stanford Health Care
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