Professor, Medicine, University of Mississippi School of Medicine
Pulmonology
Dr. John R. Spurzem, MD
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Dr. John R. Spurzem practices Pulmonology. He studied medicine at University of California Irvine School of Medicine. University of California Irvine School of Medicine has a rank of 45 in research and a 62 in primary care John Spurzem has written publications. He has 95 publications published with PubMed. The lastest paper is: 'Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells.' John Spurzem accepts Medicare payments and is registered with Medicare.gov.
Publications
- About severe sepsis and septic shock.
- Outpatient management of patients following Pulmonary embolism.
- On the diagnosis of adrenal insufficiency in severe sepsis and septic shock.
- Malondialdehyde-acetaldehyde adducts decrease bronchial epithelial wound repair.
- Alcohol intake is associated with altered Pulmonary function.
- Pathogenesis of COPD.
- Ethanol treatment reduces bovine bronchial epithelial cell migration.
- Tumor necrosis factor-alpha hyper-responsiveness to endotoxin in whole blood is associated with chronic Bronchitis in farmers.
- Ethanol increases phosphodiesterase 4 activity in bovine bronchial epithelial cells.
- Effect of cigarette smoke on fibroblast-mediated gel contraction is dependent on cell density.
- Agricultural Lung disease.
- Activation of protein kinase A accelerates bovine bronchial epithelial cell migration.
- Interleukin-4- and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma.
- Gamma radiation inhibits fibroblast-mediated collagen gel retraction.
- Relaxin stimulates bronchial epithelial cell PKA activation, migration, and ciliary beating.
- Spontaneous production of transforming growth factor-beta 2 by primary cultures of bronchial epithelial cells. Effects on cell behavior in vitro.
- Airway inflammation predicts diffuse alveolar hemorrhage during bone marrow transplantation in patients with Hodgkin Disease.
- Extracellular matrix and bronchial epithelial cell migration.
- Airways inflammation.
- Transforming growth factor-beta stimulates the expression of desmosomal proteins in bronchial epithelial cells.
- Regional distribution of emphysema: correlation of high-resolution CT with Pulmonary function tests in unselected smokers.
- Pulmonary complications of transplantation.
- Regulation of major histocompatibility complex class II gene expression on bovine bronchial epithelial cells.
- Modulation of neutrophil and mononuclear cell adherence to bronchial epithelial cells.
- Bronchoalveolar lavage in the diagnosis of Lung cancer.
- Chronic inflammation is associated with an increased proportion of goblet cells recovered by bronchial lavage.
- Bronchoscopy with bronchoalveolar lavage causes neutrophil recruitment to the lower Respiratory tract.
- Attachment characteristics of bovine bronchial epithelial cells to extracellular matrix components.
- Protease injury in airways Disease.
- Evaluation of elastase and antielastase balance in patients with chronic Bronchitis and pulmonary emphysema.
- Expression of HLA class II genes in alveolar macrophages of patients with Sarcoidosis.
- Functional significance of anti-T-lymphocyte antibodies in Sarcoidosis.
- Sarcoidosis is not associated with a generalized defect in T cell suppressor function.
- Evaluation of the in vitro and in vivo effects of cyclosporine on the lung T-lymphocyte alveolitis of active Pulmonary sarcoidosis.
- Mechanisms of macrophage accumulation in the Lungs of asbestos-exposed subjects.
- Spontaneous release of interleukin 2 by lung T lymphocytes in active Pulmonary sarcoidosis is primarily from the Leu3+DR+ T cell subset.
- Toxic oil syndrome.
- Factitious methemoglobinemia caused by hyperlipemia.
- Substance P increases neutrophil adhesion to bronchial epithelial cells.
- Induction of bovine bronchial epithelial cell filopodia by tetradecanoyl phorbol acetate, calcium ionophore, and lysophosphatidic acid.
- Modulation of fibroblast type I collagen and fibronectin production by bovine bronchial epithelial cells.
- Cigarette smoke inhibits Lung fibroblast proliferation and chemotaxis.
- Immunological functions of the Pulmonary epithelium.
- Effects of cigarette smoke extract on bovine bronchial epithelial cell attachment and migration.
- Bovine herpesvirus-1 infection reduces bronchial epithelial cell migration to extracellular matrix proteins.
- Is Asthma an epithelial disease?
- Airway epithelial cells: functional roles in airway Disease.
- Smoke and viral infection cause cilia loss detectable by bronchoalveolar lavage cytology and dynein ELISA.
- Quantitative culture of bronchoalveolar lavage fluid for the diagnosis of bacterial Pneumonia.
- Viral infection of bovine bronchial epithelial cells induces increased neutrophil chemotactic activity and neutrophil adhesion.
- Phenol sulfotransferase expression in the airways: enzymological and immunohistochemical demonstration.
- Mechanisms of airflow obstruction: role of cells and mediators.
- Transforming growth factor-beta increases adhesion but not migration of bovine bronchial epithelial cells to matrix proteins.
- General vs local anesthesia. Effect on bronchoalveolar lavage findings.
- Migration of bovine bronchial epithelial cells to extracellular matrix components.
- The Bronchitis index. A semiquantitative visual scale for the assessment of airways inflammation.
- Aprotinin and methylprednisolone equally blunt cardioPulmonary bypass-induced inflammation in humans.
- Supraceliac, but not infrarenal, aortic cross-clamping upregulates neutrophil integrin CD11b.
- Lipopolysaccharide increases fibronectin production and release from cultured Lung fibroblasts partially through proteolytic activity.
- Mononuclear cell conditioned medium enhances bronchial epithelial cell migration but inhibits attachment to fibronectin.
- Beta-adrenergic agonists attenuate fibroblast-mediated contraction of released collagen gels.
- Function at the junction: dynamic interactions between Lung cells and extracellular matrix.
- Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells.
- Bombesin-like peptides and airway repair: a recapitulation of Lung development?
- Fibronectin supports bronchial epithelial cell adhesion and survival in the absence of growth factors.
- Mutual inhibition by TGF-beta and IL-4 in cultured human bronchial epithelial cells.
- Stimulation of protein kinase C activity by tumor necrosis factor-alpha in bovine bronchial epithelial cells.
- Selective migration of alpha-smooth muscle actin-positive myofibroblasts toward fibronectin in the Boyden''s blindwell chamber.
- Human bronchial epithelial cells can contract type I collagen gels.
- Human bronchial epithelial cells modulate collagen gel contraction by fibroblasts.
- Epithelial adhesion molecules in airway repair.
- Fibronectin production by cultured human Lung fibroblasts in three-dimensional collagen gel culture.
- Cigarette smoke extract inhibits fibroblast-mediated collagen gel contraction.
- Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells.
- Human neutrophil elastase augments fibroblast-mediated contraction of released collagen gels.
- Glucocorticoids augment fibroblast-mediated contraction of collagen gels by inhibition of endogenous PGE production.
- Two-colour flow-cytometric analysis of Pulmonary alveolar macrophages from smokers.
- IL-4 induces ICAM-1 expression in human bronchial epithelial cells and potentiates TNF-alpha.
- Sodium nitroprusside augments human Lung fibroblast collagen gel contraction independently of NO-cGMP pathway.
- Modification of type I collagenous gels by alveolar epithelial cells.
- Endothelial cell-mediated type I collagen gel contraction is regulated by hemin.
- Cigarette smoke inhibits osteogenic differentiation and proliferation of human osteoprogenitor cells in monolayer and three-dimensional collagen gel culture.
- Contraction of fibroblast-containing collagen gels: initial collagen concentration regulates the degree of contraction and cell survival.
- Persistence of TGF-beta1 induction of increased fibroblast contractility.
- Bradykinin augments fibroblast-mediated contraction of released collagen gels.
- Cytokine inhibition of fibroblast-induced gel contraction is mediated by PGE(2) and NO acting through separate parallel pathways.
- Synergistic neutrophil elastase-cytokine interaction degrades collagen in three-dimensional culture.
- Prostaglandin E(2) inhibits fibroblast chemotaxis.
- Retinoic acid attenuates cytokine-driven fibroblast degradation of extracellular matrix in three-dimensional culture.
- Cigarette smoke inhibits human bronchial epithelial cell repair processes.
- Gene expression in an in vitro model of epithelial repair.
- TGF-beta1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels.
- Adenosine promotion of cellular migration in bronchial epithelial cells is mediated by the activation of cyclic adenosine monophosphate-dependent protein kinase A.
- Adenosine A2A receptors promote adenosine-stimulated wound healing in bronchial epithelial cells.
Schools
University Of California Irvine College Of Medicine
Mayo Clinc
University of Utah
Procedures Preformed
- Bronchoscopy
- Thoracentesis
- Ventilation Management
Conditions Treated
- Acidosis
- Alkalosis
- Asthma
- Atelectasis
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Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
- Choice Plus POS II
- American Republic
- Blue Card PPO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- Emblem Health
- First Health (Coventry Health Care) PPO
- Choice Care PPO
- Mail Handlers Benefit Plan (MHBP)
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- Universal American
Education
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University of Utah -
Mayo School of Graduate Medical Education -
University of California Irvine School of Medicine
Drug Facts
| NPI NUMBER | 1467489930 | |
| NPPES Provider LastName | SPURZEM | |
| NPPES Provider FirstName | JOHN | |
| NPPES Provider ZIPCode | 392164500 | |
| NPPES Provider State | MS | |
| Specialty Description | Pulmonary Disease | |
| Total Claim Count | 1074.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 11.0 | |
| Percent Opioid Claims | 1.02 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1467489930 |
| Last Name Of The Provider | SPURZEM |
| First Name Of The Provider | JOHN |
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