Chair, Department of Pediatrics
Pediatrics
Dr. Jonathan A. McCullers, MD
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Jonathan A. McCullers works in the field of Pediatrics. He researched medicine at University of Alabama Medical Center. University of Alabama Medical Center is ranked 37 in research and 17 in primary care medicine Jonathan McCullers is also published. He has 96 publications published. The lastest publication: "Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice.'
Publications
- Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia.
- Randomized, double-blind comparison of standard-dose vs. high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients.
- NS1 mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic?
- Chronic helminth infections impair pneumococcal vaccine responses.
- Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis.
- The public health policy implications of understanding metabiosis.
- Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens.
- The co-pathogenesis of influenza viruses with bacteria in the lung.
- The immune profile associated with acute allergic asthma accelerates clearance of influenza virus.
- Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice.
- Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia.
- A novel cytotoxic sequence contributes to influenza A protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection.
- Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections.
- Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.
- Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae.
- Do specific virus-bacteria pairings drive clinical outcomes of pneumonia?
- Therapeutics Against Influenza.
- Correlates of vaccine protection from influenza and its complications.
- Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine in immunocompromised children and young adults.
- Impaired Wound Healing Predisposes Obese Mice to Severe Influenza Virus Infection.
- Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer.
- No evidence of a link between influenza vaccines and Guillain-Barre syndrome-associated antiganglioside antibodies.
- Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82.
- Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.
- Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden in pregnant mice.
- Receptor-Binding Specificity of the Human Parainfluenza Virus Type 1 Hemagglutinin-Neuraminidase Glycoprotein.
- Motivating factors for high rates of influenza vaccination among healthcare workers.
- Mathematical model of a three-stage innate immune response to a pneumococcal lung infection.
- Immunotherapy with a combination of intravenous immune globulin and p4 peptide rescues mice from postinfluenza pneumococcal pneumonia.
- Safety of live attenuated influenza vaccine in mild to moderately immunocompromised children with cancer.
- Preventing and treating secondary bacterial infections with antiviral agents.
- Influenza virus primes mice for pneumonia from Staphylococcus aureus.
- Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice.
- Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics.
- Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats.
- Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets.
- Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus.
- Contribution of vaccine-induced immunity toward either the HA or the NA component of influenza viruses limits secondary bacterial complications.
- Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?
- PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology.
- The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis.
- A practical guide to alcohol-based hand hygiene infrastructure in a resource-poor pediatric hospital.
- Use of atmospheric non-thermal plasma as a disinfectant for objects contaminated with methicillin-resistant Staphylococcus aureus.
- Are toilet seats a vector for transmission of methicillin-resistant Staphylococcus aureus?
- A multi-valent vaccine approach that elicits broad immunity within an influenza subtype.
- Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza.
- Live, attenuated influenza virus (LAIV) vehicles are strong inducers of immunity toward influenza B virus.
- Preparing for the next influenza pandemic.
- Vaccines against pandemic influenza: what can be done before the next pandemic?
- Planning for an influenza pandemic: thinking beyond the virus.
- c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection.
- Improving therapeutic strategies for secondary bacterial pneumonia following influenza.
- FluBlok, a recombinant influenza vaccine.
- Advances in vaccine technology and their impact on managed care.
- Planning and implementation of an infection control training program for healthcare providers in Latin America.
- Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia.
- The platelet activating factor receptor is not required for exacerbation of bacterial pneumonia following influenza.
- Evolution, benefits, and shortcomings of vaccine management.
- Chloroquine is effective against influenza A virus in vitro but not in vivo.
- N-linked glycosylation attenuates H3N2 influenza viruses.
- Novel strategy to prevent otitis media caused by colonizing Streptococcus pneumoniae.
- Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza.
- Distinct contributions of vaccine-induced immunoglobulin G1 (IgG1) and IgG2a antibodies to protective immunity against influenza.
- A step closer to meeting the threat of avian influenza.
- Insights into the interaction between influenza virus and pneumococcus.
- Early vancomycin therapy and adverse outcomes in children with pneumococcal meningitis.
- Bacterial sinusitis and otitis media following influenza virus infection in ferrets.
- The clinical need for new antiviral drugs directed against influenza virus.
- Live attenuated influenza vaccine is safe and immunogenic in immunocompromised ferrets.
- Increased influenza vaccination of healthcare workers at a pediatric cancer hospital: results of a comprehensive influenza vaccination campaign.
- Influenza virus neuraminidase contributes to secondary bacterial pneumonia.
- A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence.
- WASP- mice exhibit defective immune responses to influenza A virus, Streptococcus pneumoniae, and Mycobacterium bovis BCG.
- Antiviral therapy of influenza.
- The novel parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae.
- Multiple genotypes of influenza B virus circulated between 1979 and 2003.
- Association between tea ingestion and invasive Bacillus cereus infection among children with cancer.
- Wild-type and attenuated influenza virus infection of the neonatal rat brain.
- Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza.
- Levels of total fungus and Aspergillus on a pediatric hematopoietic stem cell transplant unit.
- Respiratory viruses predisposing to bacterial infections: role of neuraminidase.
- Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae.
- Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor.
- Pneumococcal meningitis in children: relationship of antibiotic resistance to clinical characteristics and outcomes.
- Molecular pathogenesis of pneumococcal pneumonia.
- Bacillus cereus bacteremia and meningitis in immunocompromised children.
- Candidal meningitis in children with cancer.
- Isolation and characterization of vancomycin-tolerant Streptococcus pneumoniae from the cerebrospinal fluid of a patient who developed recrudescent meningitis.
- Reassortment and insertion-deletion are strategies for the evolution of influenza B viruses in nature.
- Influenza B virus encephalitis.
- Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice.
- Candida tropicalis osteomyelitis: case report and review.
- Human herpesvirus 6 is associated with focal encephalitis.
- Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions.
- Non-Avian Animal Reservoirs Present a Source of Influenza A PB1-F2 Proteins with Novel Virulence-Enhancing Markers.
Schools
University of Alabama At Birmingham
University Of Al Hospital
Doctors Specialties
- Pediatric Infectious Disease Medicine
- Pediatrics
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- Network S
- Great West Healthcare-Cigna PPO
- Commercial Insurance Company
- First Health (Coventry Health Care) PPO
- Medicaid
- Medicare MCR
- PHCS Network PPO
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Education
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University of Alabama Medical Center -
University of Alabama School of Medicine
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