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Allergy & Immunology
Dr. Joost J. Oppenheim, MD
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Doctor Joost J. Oppenheim, MD is an expert in the field of Allergy & Immunology. He researched medicine at Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a top medical university. Columbia University College of Physicians & Surgeons is ranked 8 in research and 52 in primary care medicine He over the years received 1 awards: "Whos Who in Medicine and Healthcare". Joost Oppenheim is a published physician as well. He has 101 publications published. The latest was: Deficient DR antigen expression on human neonatal monocytes: reversal with lymphokines.
Publications
- Harnessing the alarmin HMGN1 for anticancer therapy.
- Characterization of MT-2 cells as a human regulatory T cell-like cell line.
- Erratum for Jelacic et al., Exposure to Bacillus anthracis Capsule Results in Suppression of Human Monocyte-Derived Dendritic Cells.
- The Alarmin HMGN1 Contributes to Antitumor Immunity and Is a Potent Immunoadjuvant.
- Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways.
- Exposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cells.
- Th17 cells and Tregs: unlikely allies.
- Progranulin promotes TNF-induced proliferation of suppressive mouse CD4(+) Foxp3(+) regulatory T cells.
- In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo.
- β-Defensin 2 and 3 Promote the Uptake of Self or CpG DNA, Enhance IFN-α Production by Human Plasmacytoid Dendritic Cells, and Promote Inflammation.
- Monocyte Chemoattractant Protein-1/CCL2 Produced by Stromal Cells Promotes Lung Metastasis of 4T1 Murine Breast Cancer Cells.
- TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment.
- DEXterity of tolerogenic APCs.
- High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
- Comment on "Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis".
- Myeloid cells migrate in response to IL-24.
- Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles.
- The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4(+) FoxP3(+) regulatory T cells.
- Resolving the identity myth: Key markers of functional CD4(+)FoxP3(+) regulatory T cells.
- Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons.
- Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity.
- TNF by inducing co-stimulatory TNF receptor superfamily members TNFR2, 4-1BB and OX40 augments the number and function of mouse CD4(+) FoxP3(+) regulatory T cells.
- PKC{zeta} mediates {micro}-opioid receptor-induced cross-desensitization of CCR5.
- Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties.
- Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture.
- Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.
- Expression of costimulatory TNFR2 induces resistance of CD4+FoxP3- conventional T cells to suppression by CD4+FoxP3+ regulatory T cells.
- Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.
- Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells.
- [Gd@C(82)(OH)(22)](n) nanoparticles induce dendritic cell maturation and activate Th1 immune responses.
- The 2008 Dolph Adams award and the state of the journal of leukocyte biology.
- Passing the torch.
- Chemerin reveals its chimeric nature.
- Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but func...
- Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory ...
- Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
- Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3.
- The 2007 Dolph Adams Award and the state of the Journal of Leukocyte Biology.
- Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
- IL-2: more than a T cell growth factor.
- Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.
- Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells.
- High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin.
- Alarmins initiate host defense.
- Adenosine A2a receptors induce heterologous desensitization of chemokine receptors.
- IL-1 can act as number one.
- Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems.
- Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleu...
- Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.
- Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking.
- Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity.
- BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice.
- Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling.
- Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.
- Autoantigens act as tissue-specific chemoattractants.
- Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and act...
- A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1.
- Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.
- Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis.
- Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation.
- Antimicrobial proteins act as "alarmins" in joint immune defense.
- Effects of IL-7 and dexamethasone: induction of CD25, the high affinity IL-2 receptor, on human CD4+ cells.
- Temporin A and related frog antimicrobial peptides use formyl peptide receptor-like 1 as a receptor to chemoattract phagocytes.
- Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor.
- Proinflammatory chemokines, such as C-C chemokine ligand 3, desensitize mu-opioid receptors on dorsal root ganglia neurons.
- Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation.
- Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense.
- Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization.
- Cutting edge: vasoactive intestinal peptide acts as a potent suppressor of inflammation in vivo by trans-deactivating chemokine receptors.
- Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells.
- Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.
- Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1.
- Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.
- Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity.
- Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3.
- Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses.
- Ca2+-independent protein kinase Cs mediate heterologous desensitization of leukocyte chemokine receptors by opioid receptors.
- 2002 Dolph Adams Award.
- Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1alpha.
- Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.
- The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins.
- Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.
- Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.
- Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain.
- Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma...
- Evolution of the serendipitous discovery of macrophage-lymphocyte interactions.
- Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer.
- Impaired production of T-lymphocyte mitogens in pediatric malignant disease.
- Polyribosomes in Azotobacter vinelandii. I. Isolation, characterization and distribution of ribosomes, polyribosomes and subunits in logarithmically growing azotobacter.
- Human lymphoproliferative reaction to saliva and dental plaque-deposits: an in vitro correlation with periodontal disease.
- Radioprotection with cytokines--learning from nature to cope with radiation damage.
- Lymphocyte transformation in mixed leukocyte cultures in women with normal pregnancy or tumors of placental origin. A preliminary report.
- [Assays for lymphocyte activation (author''s transl)].
- Labile inhibitor of lymphocyte transformation in plasma from a patient and subacute sclerosing panencephalitis.
- Immunocytochemical localization of the [3H]estradiol-binding protein in rat pancreatic acinar cells.
- Isolation and properties of the RepA1 protein of the IncFII replicon, RepFIC.
- EFFECTS OF ENDOTOXINS ON CULTURED LEUKOCYTES.
- Histamine release from human leucocytes by concanavalin A and other mitogens.
- Phytohemagglutinin as a skin test for the evaluation of cellular immune competence in man.
- Deficient DR antigen expression on human neonatal monocytes: reversal with lymphokines.
Schools
Columbia University College of Physicians And Surgeons
Doctors Specialties
- Allergy
- Immunology
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
Education
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Columbia University College of Physicians & Surgeons
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