Professor of Surgery, Massachusetts General Hospital
Thoracic Surgery
Dr. Joren C. Madsen, MD
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Joren C. Madsen, MD is an expert in the field of Thoracic Surgery. He attended University of Massachusetts Medical School. University of Massachusetts Medical School has a rank of 49 in research and a 12 in primary care He received 1 awards: "Fellow (FACS)". Joren Madsen is a published doctor and has 66 publications published. The lastest was: 'Organ Transplant Tolerance for Children; in Sight for Some.'
Publications
- Effects of Lung Cotransplantation on Cardiac Allograft Tolerance Across a Full Major Histocompatibility Complex Barrier in Miniature Swine.
- Organ Transplant Tolerance for Children; in Sight for Some.
- A novel approach to measuring cell-mediated lympholysis using quantitative flow and imaging cytometry.
- Recipient-Matching of Passenger Leukocytes Prolongs Survival of Donor Lung Allografts in Miniature Swine.
- Immunomodulatory Strategies Directed Toward Tolerance of Vascularized Composite Allografts.
- Long-Term Lung Transplantation in Nonhuman Primates.
- Use of CTLA4Ig for Induction of Mixed Chimerism and Renal Allograft Tolerance in Nonhuman Primates.
- Depletion of T regulatory cells promotes natural killer cell-mediated cardiac allograft vasculopathy.
- Depletion of foxp3(+) T cells abrogates tolerance of skin and Heart allografts in murine mixed chimeras without the loss of mixed chimerism.
- Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo.
- Tolerance: One Transplant for Life.
- Successful Right Ventricular Mechanical Support after Combined Heart-Liver Transplantation.
- Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells.
- Predictors of Survival to Orthotopic Heart Transplant in Patients with Light Chain Amyloidosis.
- Induction of Cardiac Allograft Tolerance Across a Full MHC Barrier in Miniature Swine by Donor Kidney Cotransplantation.
- Role of Complement and NK Cells in Antibody Mediated Rejection.
- Low-Dose IL-2 for In Vivo Expansion of CD4(+) and CD8(+) Regulatory T Cells in Nonhuman Primates.
- Differential Effects of Denileukin Diftitox IL-2 Immunotoxin on NK and Regulatory T Cells in Nonhuman Primates.
- Donor Brain Death Inhibits Tolerance Induction in Miniature Swine Recipients of Fully MHC-Disparate Pulmonary Allografts.
- Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human p...
- Innate NK cells and macrophages recognize and reject allogeneic nonself in vivo via different mechanisms.
- Contributions of Direct and Indirect Alloresponses to Chronic Rejection of Kidney Allografts in Nonhuman Primates.
- Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys.
- Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates.
- Coronary artery disease from isolated non-h2-determined incompatibilities in transplanted mouse Hearts.
- Autoimmune Sensitization to Cardiac Myosin Leads to Acute Rejection of Cardiac Allografts in Miniature Swine.
- Early acceptance of renal allografts in mice is dependent on foxp3(+) cells.
- Natural killer cells in rejection and tolerance of solid organ allografts.
- Cost-related immunosuppressive medication nonadherence among kidney transplant recipients.
- Innate immunity and cardiac allograft rejection.
- Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and Heart failure.
- Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3{beta} inhibition.
- Surgical management and long-term outcomes for acute ascending aortic dissection.
- Innate immunity in Heart transplantation.
- The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts.
- Immunosuppression for lung transplantation.
- Repetitive gastric aspiration leads to augmented indirect allorecognition after lung transplantation in miniature swine.
- The need for tolerance in pediatric organ transplantation.
- Management of Coronary artery compression caused by recurrent aortic root abscess.
- The effects of tolerance on allograft damage caused by the innate immune system.
- Mechanisms of chronic rejection in cardiothoracic transplantation.
- Operational tolerance to class I disparate lungs can be induced despite pretransplant immunization with class I allopeptides.
- The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells.
- Tolerance, xenotransplantation: future therapies.
- The changing role of natural killer cells in solid organ rejection and tolerance.
- Combination treatment with donor-specific transfusions and cyclosporine a induces long-term survival of cardiac allografts in miniature Swine.
- NK cells can trigger allograft vasculopathy: the role of hybrid resistance in solid organ allografts.
- Heart and en-bloc thymus transplantation in miniature swine.
- Role of the thymus and kidney graft in the maintenance of tolerance to Heart grafts in miniature swine.
- Aortic valve replacement in patients with previous cardiac surgery.
- Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidney with Heart transplantation.
- Constitutive expression of major histocompatibility complex class II antigens in pulmonary epithelium and endothelium varies among different species.
- Feasibility of xeno-transplantation.
- Histomorphometric comparison of cardiac allograft vasculopathy in miniature swine.
- Induction of tolerance to Heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population.
- Histocompatible miniature swine: an inbred large-animal model.
- Results of bioprosthetic versus mechanical aortic valve replacement performed with concomitant Coronary artery bypass grafting.
- A novel technique for en bloc, vascularized, composite thymic, and cardiac co-transplantation1.
- Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeys.
- Combined Heart and kidney transplantation: are two organs better than one?
- Overcoming cardiac allograft vasculopathy (CAV) by inducing tolerance.
- Modeling chronic lung allograft rejection in miniature swine.
- Endoscopic versus open saphenous vein harvest: a comparison of postoperative wound complications.
- Cytokines in immunity and allograft rejection.
- Heart transplantation: challenges facing the field.
Schools
University of Massachusetts Worcester Campus
Massachusetts General Hospital
Mass Genl Hospital Chldns Hospital
Conditions Treated
- Arrhythmias (incl. Atrial Fibrillation)
- Cardiomyopathy
- Congenital Heart Disease
- Congestive Heart Failure
- View All
Doctors Specialties
- Cardiac Surgery
- Thoracic Surgery
Accepted Insurances
Awards
- Fellow (FACS)
Education
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Massachusetts General Hospital -
University of Massachusetts Medical School
Hospital
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Massachusetts General Hospital
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