Professor
Pediatric Hematology & Oncology
Dr. Julio C. Barredo, MD
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Dr. Julio C. Barredo is an expert in the field of Pediatric Hematology & Oncology. He has 4 awards "America's Top Doctors", "America's Top Doctors for Cancer", "Top Doctors:South Florida" and "Super Doctor". Julio Barredo is a published doctor as well. He has 43 publications published. The latest was: Postdural puncture headache in paediatric oncology patients.
Publications
- AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in Acute lymphoblastic leukemia.
- The pediatric hydroxyurea phase III clinical trial (BABY HUG): challenges of study design.
- Serum ferritin level changes in children with sickle cell disease on Chronic blood transfusion are nonlinear and are associated with iron load and liver injury.
- Successful use of fondaparinux as an alternative anticoagulant in a 2-month-old infant.
- Isolated CNS relapse of Acute lymphoblastic leukemia treated with intensive systemic chemotherapy and delayed CNS radiation: a pediatric oncology group study.
- Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human Leukemia CCRF-CEM and Nalm-6 cell lines.
- Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts.
- A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid, ...
- Hereditary erythrocyte adenylate kinase deficiency: a defect of multiple phosphotransferases?
- A microassay for mammalian folylpolyglutamate synthetase.
- Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development.
- Pleuropulmonary blastoma: a marker for familial Disease.
- Bone marrow transplantation for sickle cell Anemia.
- Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells.
- Myelodysplasia Associated with Turner syndrome.
- Controversies in the management of central nervous system Leukemia.
- Management of paranasal sinus malignancy.
- Improved survival of children with isolated CNS relapse of Acute lymphoblastic leukemia: a pediatric oncology group study .
- Renal kallikrein: a risk marker for nephropathy in children with sickle cell Disease.
- Neurologic complications following bone marrow transplantation for sickle cell Disease.
- Survival With combined modality therapy after intracerebral recurrence of pleuropulmonary blastoma.
- Successful treatment of relapsed infant Acute lymphoblastic leukemia with intensive antimetabolite-based chemotherapy.
- All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic Disorders.
- Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage d...
- Transient therapy-related myelodysplastic syndrome Associated with monosomy 7 and 11q23 translocation.
- Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update.
- Progressive autologous Graft-versus-host disease induced by cyclosporin A.
- Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage Leukemia.
- Effects of radiation and 4-hydroperoxycyclophosphamide on production of G- and GM-CSF by stromal cells.
- Folylpoly-gamma-glutamate synthetase gene mRNA splice variants and protein expression in primary human Leukemia cells, cell lines, and normal human tissues.
- Assessment of barriers to bone marrow donation by unrelated African-American potential donors.
- Effects of cranial radiation in children with high risk T cell Acute lymphoblastic leukemia: a Pediatric Oncology Group report.
- Increased expression of lung resistance-related protein and multidrug resistance-associated protein messenger RNA in childhood Acute lymphoblastic leukemia.
- Postdural puncture headache in paediatric oncology patients.
- Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood Acute lymphoblastic le...
- Outcomes after HLA-matched sibling transplantation or chemotherapy in children with Acute lymphoblastic leukemia in a second remission after an isolated central nervou...
- Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood Acute lymphoblastic leukemia (ALL) cells: implication for targeted ther...
- Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line.
- AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in Acute lymphoblastic leukemia.
- Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in Acute lymphoblastic leukemia.
- Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cells.
- Hydroxycarbamide in very young children With sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).
Procedures Preformed
- Plasmapheresis
Conditions Treated
- Acute Leukemia
- Adrenal Gland Cancer
- Anemia
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
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Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- Top Doctors:South Florida
- Super Doctor
Education
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Children's Hospital of Los Angeles -
SUNY Health Science Center at Brooklyn -
National University of San Marcos
Hospital
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Nicklaus Children's Hospital
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