Professor
Pediatric Infectious Disease
Dr. Katherine L. O'Brien, MD
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Katherine L. O'Brien, MD is an expert in the field of Pediatric Infectious Disease. She over the years received 2 awards: "Presidents Early Career Award in Science and Engineering" and "Sabin Young Scientist Award". Katherine O'Brien is a published doctor and has 89 publications published. The lastest was: 'Global Burden of Neonatal Invasive Pneumococcal Disease: A Systematic Review and Meta-analysis.'
Publications
- Global Burden of Neonatal Invasive Pneumococcal Disease: A Systematic Review and Meta-analysis.
- Individual level determinants for not receiving immunization, receiving immunization with delay, and being severely underimmunized among rural western Kenyan children.
- Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-control...
- Persistence of IgG Antibody Following Routine Infant Immunization with the 7-Valent Pneumococcal Conjugate Vaccine.
- Is the world ready for an Ebola vaccine?
- Impact of the Hajj on pneumococcal transmission.
- Nasopharyngeal Carriage and Transmission of Streptococcus pneumoniae in American Indian Households after a Decade of Pneumococcal Conjugate Vaccine Use.
- Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: Updated recommendations from the World Health Organization Pneumococcal Carriage ...
- Leaning in to the Power of the Possible: The Crucial Role of Women Scientists on Preventing Haemophilus influenzae Type b Disease.
- Seasonal drivers of pneumococcal disease incidence: Impact of bacterial carriage and viral activity.
- Serotype-Specific Changes in Invasive Pneumococcal Disease after Pneumococcal Conjugate Vaccine Introduction: A Pooled Analysis of Multiple Surveillance Sites.
- Impact of pneumococcal conjugate vaccines on nasopharyngeal invasive disease among unvaccinated people: Review of evidence on indirect effects.
- Global burden of childhood pneumonia and diarrhoea.
- A Prospective Study of Agents Associated with Acute Respiratory Infection among Young American Indian Children.
- Nontypeable pneumococcal isolates among navajo and white mountain apache communities: are these really a cause of invasive disease?
- Specimen collection for the diagnosis of pediatric pneumonia.
- Evaluation of risk factors for severe pneumonia in children: the Pneumonia Etiology Research for Child Health study.
- Identification and selection of cases and controls in the Pneumonia Etiology Research for Child Health project.
- The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology study.
- Disk diffusion bioassays for the detection of antibiotic activity in body fluids: applications for the Pneumonia Etiology Research for Child Health project.
- Procedures for collection of induced sputum specimens from children.
- A literature review and survey of childhood pneumonia etiology studies: 2000-2010.
- Impact of More Than a Decade of Pneumococcal Conjugate Vaccine Use on Carriage and Invasive Potential in Native American Communities.
- Pneumococcal sequence type replacement among American Indian children: A comparison of pre- and routine-PCV7 eras.
- The epidemiologic evidence underlying recommendations for use of pneumococcal polysaccharide vaccine among American Indian and Alaska Native populations.
- Maternal influenza vaccination and effect on influenza virus infection in young infants.
- Pre- and post-conjugate vaccine epidemiology of pneumococcal serotype 6C invasive disease and carriage within Navajo and White Mountain Apache communities.
- A policy framework for accelerating adoption of new vaccines.
- Systematic evaluation of serotypes causing invasive pneumococcal disease among children under five: the pneumococcal global serotype project.
- Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis.
- Revisiting pneumococcal carriage by use of broth enrichment and PCR techniques for enhanced detection of carriage and serotypes.
- Invasive pneumococcal disease a decade after pneumococcal conjugate vaccine use in an American Indian population at high risk for disease.
- Breathing new life into pneumonia diagnostics.
- Pneumococcal conjugate vaccine, polysaccharide vaccine, or both for adults? We're not there yet.
- Nasopharyngeal carriage of Streptococcus pneumoniae in Navajo and White Mountain Apache children before the introduction of pneumococcal conjugate vaccine.
- Pneumococcal vaccine and the dance of the veils: revealing pneumonia burden in Asia.
- Impact of immunizations on the disease burden of American Indian and Alaska native children.
- Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household members.
- Young infants can develop protective levels of neutralizing antibody after infection with respiratory syncytial virus.
- Changing epidemiology of invasive pneumococcal disease among White Mountain Apache persons in the era of the pneumococcal conjugate vaccine.
- Invasive pneumococcal disease among White Mountain Apache adults, 1991-2005.
- The role of neutralizing antibodies in protection of American Indian infants against respiratory syncytial virus disease.
- The evidence for using conjugate vaccines to protect HIV-infected children against pneumococcal disease.
- Randomized, controlled trial efficacy of pneumococcal conjugate vaccine against otitis media among Navajo and White Mountain Apache infants.
- Risk factors for invasive pneumococcal disease among Navajo adults.
- Effect of pneumococcal conjugate vaccine on nasopharyngeal colonization among immunized and unimmunized children in a community-randomized trial.
- Strain characteristics of Streptococcus pneumoniae carriage and invasive disease isolates during a cluster-randomized clinical trial of the 7-valent pneumococcal conju...
- Combined schedules of pneumococcal conjugate and polysaccharide vaccines: is hyporesponsiveness an issue?
- Predictors of pneumococcal conjugate vaccine immunogenicity among infants and toddlers in an American Indian PnCRM7 efficacy trial.
- Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence.
- Anticapsular serum antibody concentration and protection against pneumococcal colonization among children vaccinated with 7-valent pneumococcal conjugate vaccine.
- Effect of community-wide conjugate pneumococcal vaccine use in infancy on nasopharyngeal carriage through 3 years of age: a cross-sectional study in a high-risk popula...
- Modeling the association between pneumococcal carriage and child-care center attendance.
- Epidemiology of invasive Haemophilus influenzae type A disease among Navajo and White Mountain Apache children, 1988-2003.
- Delivering pneumococcal vaccine to a high risk population: the Navajo experience.
- Nasopharyngeal versus oropharyngeal sampling for detection of pneumococcal carriage in adults.
- Epidemiology of invasive Streptococcus pneumoniae among Navajo children in the era before use of conjugate pneumococcal vaccines, 1989-1996.
- Potential impact of conjugate pneumococcal vaccines on pediatric pneumococcal diseases.
- Immunoblot method to detect Streptococcus pneumoniae and identify multiple serotypes from nasopharyngeal secretions.
- Invasive pneumococcal disease among Navajo adults, 1989-1998.
- Impact of intrapartum antibiotics on the care and evaluation of the neonate.
- Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysacch...
- Effectiveness of the 23-valent polysaccharide vaccine against invasive pneumococcal disease in Navajo adults.
- Epidemiology of invasive group a streptococcus disease in the United States, 1995-1999.
- Respiratory syncytial virus infection in Navajo and White Mountain Apache children.
- Integrated monitoring of a new group B streptococcal disease prevention program and other perinatal infections.
- The Human ABCG1 Transporter Mobilizes Plasma Membrane and Late Endosomal Non-Sphingomyelin-Associated-Cholesterol for Efflux and Esterification.
- Cellular Localization and Trafficking of the Human ABCG1 Transporter.
- Comparative Immunogenicity of 7 and 13-Valent Pneumococcal Conjugate Vaccines and the Development of Functional Antibodies to Cross-Reactive Serotypes.
- Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.
- Could a single dose of pneumococcal conjugate vaccine in children be effective? Modeling the optimal age of vaccination.
- Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies.
- The potential indirect effect of conjugate pneumococcal vaccines.
- Report from a WHO Working Group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae.
- Trends in incidence and antimicrobial resistance of early-onset sepsis: population-based surveillance in San Francisco and Atlanta.
- Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: group randomised trial.
- Pneumococcal vaccination in developing countries.
- Standardizing surveillance of pneumococcal disease.
- Pneumococcal antibodies in a child with type 14 pneumococcal conjugate vaccine failure.
- Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies.
- Invasive pneumococcal disease epidemiology and effectiveness of 23-valent pneumococcal polysaccharide vaccine in Alaska native adults.
- Effectiveness of pneumococcal conjugate vaccine.
- Contributions of Native Americans to the global control of infectious diseases.
- Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates.
- Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates.
- Efficacy of a Pentavalent Human-bovine Reassortant Rotavirus Vaccine Against Rotavirus Gastroenteritis Among American Indian Children.
- The burden of acute respiratory infections in crisis-affected populations: a systematic review.
- Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis.
Schools
McGill University Faculty of Medicine
Johns Hopkins Hospital
Doctors Specialties
- Pediatric Infectious Disease Medicine
- Pediatric Infectious Disease
Accepted Insurances
Awards
- Presidents Early Career Award in Science and Engineering
- Sabin Young Scientist Award
Education
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Johns Hopkins School of Hygiene and Public Health -
Johns Hopkins University -
McGill University Faculty of Medicine
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