Chairman
Neurosurgery
Dr. Keith L. Black, MD
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Keith Black is an expert in the field of Neurosurgery. He graduated from University of Michigan Medical School. He has 8 awards "America's Top Doctors", "Top Doctors:LA Area", "America's Top Doctors for Cancer", "Top Doctors:Southern California", "Super Doctor", "Whos Who in Medicine and Healthcare", "Fellow (FAANS)" and "Top MD". Keith Black is a published doctor and has 87 publications published. The lastest was: 'Multiple resections and survival of recurrent glioblastoma patients in the temozolomide era.' He accepts all Medicare patients.
Publications
- Multiple resections and survival of recurrent Glioblastoma patients in the temozolomide era.
- Unplanned readmissions and survival following Brain tumor surgery.
- ACE Overexpression in Myelomonocytic Cells: Effect on a Mouse Model of Alzheimer's Disease.
- Treatment and survival of patients harboring histological variants of Glioblastoma.
- Intrinsically de-sialylated CD103(+) CD8 T cells mediate beneficial anti-Glioma immune responses.
- Does 30-day readmission affect long-term outcome among Glioblastoma patients?
- Near-infrared imaging of Brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of Brain tumors.
- Clinical experience with a high definition exoscope System for surgery of pineal region lesions.
- Cystic Glioblastoma: An Evaluation of IDH1 Status and Prognosis.
- Effectiveness of radiotherapy for elderly patients with anaplastic Gliomas.
- The Somatic Genomic Landscape of Glioblastoma.
- Survival and prognostic factors of anaplastic Gliomas.
- Comparison of Survival Between Cerebellar and Supratentorial Glioblastoma Patients: Surveillance, Epidemiology, and End Results (SEER) Analysis.
- Gene expression changes in rat Brain after short and long exposures to particulate matter in Los Angeles basin air: Comparison with human Brain tumors.
- Reactive oxygen species responsive nanoprodrug to treat intracranial Glioblastoma.
- Urinary tract infections in meningioma patients: analysis of risk factors and outcomes.
- Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed Glioblastoma.
- Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers.
- High levels of phosphorylated MAP kinase are associated with poor survival among patients with Glioblastoma during the temozolomide era.
- Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era.
- Infratentorial supracerebellar resection of a pineal Tumor using a high definition video exoscope (VITOM®).
- Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease.
- The optimization of polymalic acid peptide copolymers for endosomolytic drug delivery.
- Polymalic acid-based nanobiopolymer provides efficient Systemic breast cancer treatment by inhibiting both HER2/neu receptor synthesis and activity.
- Nanoplatforms for constructing new approaches to Cancer treatment, imaging, and drug delivery: what should be the policy?
- Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.
- Fluorescence lifetime spectroscopy for guided therapy of Brain tumors.
- Connective tissue growth factor associated with oncogenic activities and drug resistance in Glioblastoma multiforme.
- Temozolomide delivery to Tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid).
- Inhibition of Brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected].
- Intraoperative delineation of primary Brain tumors using time-resolved fluorescence spectroscopy.
- Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes.
- Glioma stem cell research for the development of immunotherapy.
- Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic Brain tumor models.
- T cells enhance stem-like properties and conditional malignancy in Gliomas.
- Chemokine CXC receptor 4--mediated Glioma tumor tracking by bone marrow--derived neural progenitor/stem cells.
- Antigen-specific T-cell response from dendritic cell vaccination using Cancer stem-like cell-associated antigens.
- High-resolution genomic copy number profiling of Glioblastoma multiforme by single nucleotide polymorphism DNA microarray.
- Hedgehog signaling regulates Brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas.
- Long-term survival in a child with a central Nervous system medulloepithelioma.
- Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in Glioblastoma multiforme.
- Nonsteroidal anti-inflammatory drugs suppress Glioma via 15-hydroxyprostaglandin dehydrogenase.
- Vaccination elicits correlated immune and clinical responses in Glioblastoma multiforme patients.
- Increase in Brain tumor permeability in glioma-bearing rats with nitric oxide donors.
- A high-definition exoscope System for neurosurgery and other microsurgical disciplines: preliminary report.
- Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive Cancer stem-like cells.
- Manipulation of proliferation and differentiation of human bone marrow-derived neural stem cells in vitro and in vivo.
- Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of Glioma cells in vitro and in vivo.
- Induction of potent antiTumor immunity by intraTumoral injection of interleukin 23-transduced dendritic cells.
- A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyros...
- Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial Glioma.
- Polycefin, a new prototype of a multifunctional nanoconjugate based on poly(beta-L-malic acid) for drug delivery.
- Changes in laminin isoforms associated with Brain tumor invasion and angiogenesis.
- Improving the delivery of therapeutic agents to CNS neoplasms: a clinical review.
- Mahaley Clinical Research Award: chemosensitization of Glioma through dendritic cell vaccination.
- Diagnosis of meningioma by time-resolved fluorescence spectroscopy.
- Dendritic cell vaccines and immunity in Glioma patients.
- T cell immunity in patients with malignant Glioma: recent progress in dendritic cell-based immunotherapeutic approaches.
- Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing Glioma.
- Clinical responsiveness of Glioblastoma multiforme to chemotherapy after vaccination.
- Association between laminin-8 and glial Tumor grade, recurrence, and patient survival.
- Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant Glioma.
- HER-2, gp100, and MAGE-1 are expressed in human Glioblastoma and recognized by cytotoxic T cells.
- Fluorescence lifetime spectroscopy of Glioblastoma multiforme.
- AIM-2: a novel tumor antigen is expressed and presented by human Glioma cells.
- Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4.
- Modulation of Brain tumor capillaries for enhanced drug delivery selectively to Brain tumor.
- Recent progress in immunotherapy for malignant Glioma: treatment strategies and results from clinical trials.
- Characterization of defective CD4-CD8- T cells in murine Tumors generated independent of antigen specificity.
- Cellular immunity in the treatment of Brain tumors.
- Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-Brain tumor barrier permeability increase in a rat Brain tumor model.
- Thymic CD8+ T cell production strongly influences tumor antigen recognition and age-dependent Glioma mortality.
- Antisense inhibition of laminin-8 expression reduces invasion of human Gliomas in vitro.
- Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant Glioma.
- Development of an intracranial ependymoma at the site of a pre-existing cavernous malformation.
- Intratumoral dendritic cell vaccination elicits potent tumoricidal immunity against malignant Glioma in rats.
- DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in Brain tumors.
- Measurement of blood-Brain and blood-tumor barrier permeabilities with [14C]-labeled tracers.
- Induction of Glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand.
- Generation of neural progenitor cells from whole adult bone marrow.
- The use of interleukin 12-secreting neural stem cells for the treatment of intracranial Glioma.
- Increased endothelial vesicular transport correlates with increased blood-Tumor barrier permeability induced by bradykinin and leukotriene C4.
- Regulation of blood-Brain tumor barrier permeability by calcium-activated potassium channels.
- A herpes simplex virus type 1 mutant with gamma 34.5 and LAT deletions effectively oncolyses human U87 Glioblastomas in nude mice.
- Trends in surgical use and associated patient outcomes in the treatment of Acoustic neuroma.
- Biopsy versus resection for the management of low-grade Gliomas.
Schools
Univ Of Mi Med Sch
University Of Michigan Hospitals
University of Michigan Ann Arbor
Procedures Preformed
- Cerebrospinal Fluid (CSF) Shunt - Insertion, Repair or Removal
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Stereotaxis
Conditions Treated
- Acoustic Neuroma
- Astrocytoma
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Cancer
- View All
Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- America's Top Doctors
- Top Doctors:LA Area
- America's Top Doctors for Cancer
- Top Doctors:Southern California
- Super Doctor
- Whos Who in Medicine and Healthcare
- Fellow (FAANS)
- Top MD
Education
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University of Michigan Hospitals and Health Centers -
University of Michigan Medical School
Hospital
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Cedars-Sinai Medical Center
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