Physician
General Surgery
Dr. Kenneth C. Appell, MD
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Dr. Kenneth C. Appell practices General Surgery. He graduated from Georgetown University School of Medicine. Georgetown University School of Medicine is ranked 49/84 in Research/PrimaryCare. Kenneth Appell has written publications. He has 36 publications published with PubMed. The lastest paper is: 'Chronic hemodialysis using venipuncture and a surgically created arteriovenous fistula. 1966.'
Publications
- Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice.
- Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.
- Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
- Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.
- Identification of CXCR3 receptor agonists in combinatorial small-molecule libraries.
- A novel high-throughput screening format to identify inhibitors of secreted acid sphingomyelinase.
- Serum creatine kinase activity and its changes after a muscle biopsy.
- Preparation and characterization of monoclonal antibodies to substance P.
- Ultra-high throughput screen of two-million-member combinatorial compound collection in a miniaturized, 1536-well assay format.
- Chronic hemodialysis using venipuncture and a surgically created arteriovenous fistula. 1966.
- Chemokine receptor-ligand interactions measured using time-resolved fluorescence.
- Anthrotainin, an inhibitor of substance P binding produced by Gliocladium catenulatum.
- WIN 64821, a novel neurokinin antagonist produced by an Aspergillus sp. II. Biological activity.
- Partial structural characterization of the cytoplasmic domain of the erythrocyte membrane protein, band 3.
- Differential scanning calorimetry of milk fat globule membranes.
- Evaluation of structural interdependence of membrane-spanning and cytoplasmic domains of band 3.
- Characterization of the reversible conformational equilibrium of the cytoplasmic domain of erythrocyte membrane band 3.
- Identification of immunoreactive forms of human erythrocyte band 3 in nonerythroid cells.
- Characterization of the stimulatory action of insulin on insulin-like growth factor II binding to rat adipose cells. Differences in the mechanism of insulin action on ...
- Insulin-induced subcellular redistribution of insulin-like growth factor II receptors in the rat adipose cell. Counterregulatory effects of isoproterenol, adenosine, a...
- Neurotransmitter release from bradykinin-stimulated PC12 cells. Stimulation of cytosolic calcium and neurotransmitter release.
- AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels.
- Antagonists that demonstrate species differences in neurokinin-1 receptors.
- Synthesis and substance P antagonist activity of naphthimidazolium derivatives.
- Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.
- Imidazo[4,5-b]quinoxaline cyanines as neurokinin antagonists.
- Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists.
- Synthesis and initial evaluation of novel, non-peptidic antagonists of the alpha(v)-integrins alpha(v)beta(3) and alpha(v)beta(5).
- Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
- Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists.
- Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.
- Identification and characterization of small-molecule inhibitors of Tie2 kinase.
- 2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.
- 2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors.
- Novel pyrrolidine heterocycles as CCR1 antagonists.
Schools
Georgetown University
Saint Vincent39s Hospital
Brooklyn Va Hospital
Doctors Specialties
- General Surgery
Accepted Insurances
Education
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Georgetown University School of Medicine