Physician
Hematology
Dr. Kit S. Lam, MD
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Kit S. Lam is an expert in the field of Hematology. He graduated from Stanford University School of Medicine. Stanford University School of Medicine is one of the top medical schools in the US. Stanford University School of Medicine has a rank of 2 in research and a 25 in primary care Kit S. Lam, MD is a published doctor and has 103 publications published. The lastest was: 'Chemically activatable viral capsid functionalized for cancer targeting.'
Publications
- Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integri...
- Unintentional Secondary exogenous corticosteroid exposure and central serous chorioretinopathy.
- Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells.
- Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells.
- A structure-property relationship study of the well-defined telodendrimers to improve hemocompatibility of nanocarriers for antiCancer drug delivery.
- Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin.
- Photopatternable and photoactive hydrogel for on-demand generation of hydrogen peroxide in cell culture.
- Telodendrimer-based nanocarriers for the treatment of ovarian Cancer.
- Antimitochondrial antibody recognition and structural integrity of the inner lipoyl domain of the e2 subunit of pyruvate dehydrogenase complex.
- Stimuli-responsive cross-linked micelles for on-demand drug delivery against Cancers.
- One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid.
- Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry.
- The core-inversible micelles for hydrophilic drug delivery.
- Reversing Bone Loss by Directing Mesenchymal Stem Cells to the Bone.
- A novel peptide inhibitor attenuates C-reactive protein's pro-inflammatory effects in-vivo.
- Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning.
- Immobilized OBOC combinatorial bead array to facilitate multiplicative screening.
- Single Cell MicroRNA Analysis Using Microfluidic Flow Cytometry.
- Synthesis and Characterization of a Novel Inhibitor of C-Reactive Protein-Mediated Proinflammatory Effects.
- Environment and primary biliary cirrhosis: Electrophilic drugs and the induction of AMA.
- Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder Cancer.
- Discovery of specific ligands for oral squamous carcinoma to develop anti-Cancer drug loaded precise targeting nanotherapeutics.
- Probing of the Assembly Structure and Dynamics within Nanoparticles during Interaction with Blood Proteins.
- Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs.
- Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.
- HER2-associated radiation resistance of breast Cancer stem cells isolated from HER2-negative breast Cancer cells.
- Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis?
- Insonation of targeted microbubbles produces regions of reduced blood flow within tumor vasculature.
- Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder Cancer.
- Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell Lymphoma.
- Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian Cancer.
- In-Vivo Biodistribution and Safety of (99m)Tc-LLP2A-HYNIC in Canine Non-Hodgkin Lymphoma.
- "OA02" Peptide Facilitates the Precise Targeting of Paclitaxel-Loaded Micellar Nanoparticles to Ovarian Cancer In Vivo.
- Well-Defined, Reversible Boronate Crosslinked Nanocarriers for Targeted Drug Delivery in Response to Acidic pH Values and cis-Diols.
- Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells.
- Affinity of the alpha4-beta1 integrin-targeting peptide LLP2A to canine Lymphoma.
- PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell Lymphoma.
- Novel Flavonoids with Antiproliferative Activities against Breast Cancer Cells.
- Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.
- Canine malignant melanoma alpha-3 integrin binding peptides.
- Rapid discovery of death ligands with one-bead-two-compound combinatorial library methods.
- Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor.
- Alzheimer's Disease drug candidates stabilize A-β protein native structure by interacting with the hydrophobic core.
- Maximization of loading and stability of ssDNA:iron oxide nanoparticle complexes formed through electrostatic interaction.
- Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents.
- The use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and Cancer targeting arginine-glyci...
- Novel poly(ethylene-co-acrylic acid) nanofibrous biomaterials for peptide synthesis and biomedical applications.
- Identification of a bladder Cancer-specific ligand using a combinatorial chemistry approach.
- Jeffamine derivatized TentaGel beads and poly(dimethylsiloxane) microbead cassettes for ultrahigh-throughput in situ releasable solution-phase cell-based screening of ...
- Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for Cancer treatment.
- Halogenated benzimidazole carboxamides target integrin alpha4beta1 on T-cell and B-cell Lymphomas.
- Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific.
- Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity.
- Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors.
- Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope.
- Structure-activity relationship studies of targeting ligands against breast Cancer cells.
- The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling.
- 111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies.
- A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells.
- Selectively targeting T- and B-cell Lymphomas: a benzothiazole antagonist of alpha4beta1 integrin.
- Discovery of targeting ligands for breast Cancer cells using the one-bead one-compound combinatorial method.
- Development of hydrogel TentaGel shell-core beads for ultrahigh throughput solution-phase screening of encoded OBOC combinatorial small molecule libraries.
- On-demand cleavable linkers for radioimmunotherapy.
- Application of the "libraries from libraries" concept to "one-bead one-compound" combinatorial chemistry.
- A novel hydrogel functionalized with specific peptidomimetic ligands for 2-D and 3-D cell culture.
- High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers.
- Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-depende...
- Glycoproteomic analyses of ovarian Cancer cell lines and sera from ovarian Cancer patients show distinct glycosylation changes in individual proteins.
- Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular Disease.
- Rainbow beads: a color coding method to facilitate high-throughput screening and optimization of one-bead one-compound combinatorial libraries.
- Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling.
- Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates.
- Screening of a one bead-one compound combinatorial library for beta-actin identifies molecules active toward Ramos B-Lymphoma cells.
- Global transformation of OBOC combinatorial peptide libraries into OBOC polyamine and small molecule libraries.
- In vivo optical imaging of human lymphoma xenoGraft using a library-derived peptidomimetic against alpha4beta1 integrin.
- Discovery of high-affinity peptide ligands for vancomycin.
- Highly potent, water soluble benzimidazole antagonist for activated alpha 4 beta 1 integrin.
- From combinatorial chemistry to Cancer-targeting peptides.
- Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization.
- Synthesis of flavonoid analogues as scaffolds for natural product-based combinatorial libraries.
- Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format.
- Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP.
- Microwave-mediated heterocyclization to benzimidazo[2,1-b]quinazolin-12(5H)-ones.
- Development of tissue plasminogen activator specific "on demand cleavable" (odc) linkers for radioimmunotherapy by screening one-bead-one-compound combinator...
- A serum glycomics approach to breast Cancer biomarkers.
- A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis.
- Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design.
- Carbodiimide-based benzimidazole library method.
- The minimum element of a synthetic peptide required to block Prostate tumor cell migration.
- Image subtraction approach to screening one-bead-one-compound combinatorial libraries with complex protein mixtures.
- Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
- Profiling of glycans in serum for the discovery of potential biomarkers for ovarian Cancer.
- Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries.
- Structure-activity relationship studies of a series of peptidomimetic ligands for alpha(4) beta(1) integrin on Jurkat T-leukemia cells.
- Near-infrared optical imaging of ovarian Cancer xenografts with novel alpha 3-integrin binding peptide "OA02".
- Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food addit...
- Identification of novel targeting peptides for human ovarian Cancer cells using "one-bead one-compound" combinatorial libraries.
- Meeting report: high-throughput technologies for in vivo imaging agents.
- Partial alloc-deprotection approach for ladder synthesis of "one-bead one-compound" combinatorial libraries.
- Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin.
- Chemically activatable viral capsid functionalized for Cancer targeting.
- LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.
Schools
Stanford University
University Med Center
Conditions Treated
- Cervical Cancer
- Coagulation Disorders (incl. Hemophilia)
- Esophageal Cancer
- Graft vs Host Disease
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Doctors Specialties
- Medical Oncology
- Oncology
- Hematology
Accepted Insurances
Education
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University of Arizona -
Stanford University School of Medicine
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